| Alternative name 1: |
Clone: 2F5, Mab anti-, UBR1 |
| Alternative name 2: |
Clone: 2F5, Mab antibody-, UBR1 |
| Alternative name 3: |
Clone: 2F5, Mab antibody-, UBR1 |
| Alternative name 4: |
anti-UBR1 Clone: 2F5 |
| Alternative name 5: |
UBR1 Clone: 2F5 |
| Clonality: |
Monoclonal Antibody |
| Description: |
Amongst the advantages of the monoclonal antibodies are: the fact that while the hybridoma takes a bit longer to be produced, If used correctly and according the protocol, in comparison to the polyclonal antibodies monoclonal antibodies are highly specific to a given epitope and can be used in applications where specific targeting is required, once the line is ready there is virtually an endless supply of these antibodie throughout time with little to no variations in recognition sites of the antigen in different batches, this antibody will provide excellent and reproducible results with guaranteed success for the tested and confirmed applications, This is a monoclonal antibody which is greatly purified and with high binding affinity for the antigen that it is risen against |
| Storage and handling: |
Antibodies in a liquid form can be shipped and stored for a short period of time at +4 degrees Celsius, antibodies that are lyophilized can be transported at ambient temperature and stored for short terms at +4 degrees Celsius, for long term storage (up to one year) 25-50% glycerol or ethylene glycol should be added and then the container has to be stored at -20°, for longer periods - at -20 , C, Generally |
| Advisory: |
For antibodies in a liquid form or reconstituted lyophilized antibodies small amounts of the soultion could be captured on the cap or the walls of the container, Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom, To keep the quality and the affinity of the antibody cycles of freezing and thawing should be avoided |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| French translation: |
anticorps |
| Gene target: |
Monoclonal 2F5, UBR1 |
| Short name: |
Mouse Monoclonal antibody- Clone: 2F5, UBR1 |
| Technique: |
Monoclonals or monoclonal antibodies, mouses, Mouse |
| Species: |
Mouses, Mouse |
| Alternative name: |
Mouse monoclonal (Antibody to)-, clonality: 2F5, ubiquitin protein ligase E3 component n-recognin 1 |
| Alternative technique: |
murine |
| Alternative to gene target: |
Cytoplasm, UBR1 and IDBG-646369 and ENSBTAG00000021087 and 522464, UBR1 and IDBG-8138 and ENSG00000159459 and 197131, Ubr1 and IDBG-201465 and ENSMUSG00000027272 and 22222, leucine binding, this GO :0000151 and ubiquitin ligase complex and cellular component this GO :0000502 and proteasome complex and cellular component this GO :0004842 and ubiquitin-protein transferase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005829 and cytosol and cellular component this GO :0006511 and ubiquitin-dependent protein catabolic process and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0016567 and protein ubiquitination and biological process this GO :0016874 and ligase activity and molecular function this GO :0030163 and protein catabolic process and biological process this GO :0032007 and negative regulation of TOR signaling and biological process this GO :0070728 and leucine binding and molecular function this GO :0071233 and cellular response to leucine and biological process, this GO :0004842 : ubiquitin-protein transferase activity, this GO :0004842 : ubiquitin-protein transferase activity and also this GO :0005515 : protein binding and also this GO :0008270 : zinc ion binding and also this GO :0016874 : ligase activity and also this GO :0070728 : leucine binding, this GO :0005515 : protein binding, this GO :0008270 : zinc ion binding, this GO :0016874 : ligase activity, this GO :0070728 : leucine binding, ubiquitin protein ligase E3 component n-recognin 1 |
| Identity: |
16808 |
| Gene: |
UBR1 |
More about : UBR1 |
| Long gene name: |
ubiquitin protein ligase E3 component n-recognin 1 |
| Locus: |
15q15, 2 |
| Discovery year: |
2002-01-25 |
| Entrez gene record: |
197131 |
| Pubmed identfication: |
9653112 |
| RefSeq identity: |
NM_174916 |
| Classification: |
Ubiquitin protein ligase E3 component n-recognins |
| Havana BLAST/BLAT: |
OTTHUMG00000130702 |