| known also as: |
Anti-Rabbit Polyclonal (IgG) to Sheep YWHAH / 14-3-3 Eta |
| known also as: |
Rabbit PAb (IgG) to Ovine YWHAH / 14-3-3 Eta |
| known also as: |
Lapin Polyclonal (IgG) to Ovinae YWHAH / 14-3-3 Eta |
| known also as: |
YWHAH / 14-3-3 Eta |
| known also as: |
14-3-3 Eta, 14-3-3 eta, 14-3-3 protein eta, Protein AS1, Sheep YWHAH, YWHA1, YWHAH, Anti-YWHAH / 14-3-3 Eta Antibody (N-Terminus) IHC-plus |
| Other names: |
14-3-3 eta, 14-3-3 protein eta, 14-3-3 protein eta, Protein AS1, eta, eta polypeptide, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, 14-3-3 protein eta |
| Gene name: |
YWHAH |
| Other gene names: |
YWHA1, YWHA1, YWHAH, YWHAH |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Chicken, Human, Mouse, Rabbit, Rat, Sheep <, /b>, Bovine, Mammal (at least 90% immunogen sequence identity), Predicted Reactivity: <, b> |
| Specificity and cross-reactivity: |
14-3-3 eta is expressed principally in the brain although it is expressed at low levels in other tissues, Furthermore the glucocorticoid receptor is positively regulated by 14-3-3- eta, It is a member of the 14-3-3 family which consists of 30 kD proteins that are involved in multiple protein kinase signalling pathways, May not react with recombinant proteins that are not N-acetylated, Protein interactions with 14-3-3 show distinct preference for it's different isoforms and are regulated by phosphorylation of both 14-3-3 and the bound protein, The eta isoform binds both gremlin 1, The protein binds alpha-synuclein, and the DAL-1/Protein 4, cytoskeletal structure, forming part of Lewy bodies in Parkinson's disease and has been linked to early-onset schizophrenia, intracellular trafficking and targeting, regulation of cell cycle progression, transcription, which is overexpressed in human cancers, 1B tumor suppressor, Recognizes 14-3-3 eta in all mammals |
| Purification method: |
Unpurified serum |
| Form/Appearance: |
0, 09% sodium azide, Serum |
| Storage and shipping: |
Avoid repeated freezing and thawing, or Store productone at -20 degrees Celsius, +Store productone at +4 degrees Celsius |
| Tested for:: |
Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| About: |
2 light chains, For storage sodium azide is added or you can call us to request azide free antibody preparations, IgG, The IgG antibody has 2 , There are 2 heavy chains, These will need colder storage temperatures, They represent 70% or more of , This antibody can be antigen purified or protein A or G purified, goat polyclonal antibodies , mouse monoclonal H&, Immunoglobulin gamma, L chain clones or rabbit, antibodies, antigen , binding sites, have 4 parts, serum |
| Gene target: |
PAb YWHAH / 14-3-3 Eta |
| Short name: |
PAb (IgG) YWHAH / 14-3-3 Eta |
| Technique: |
IgGs, IgG |
| Host: |
Sheep |
| Isotype: |
IgG |
| Species: |
An adult female sheep is referred to as a , Sheep and goats are also used to produce polyclonals, Sheeps, Some epitopes will also recognize goat proteins, The , a , and a younger sheep as a , (Ovis aries) ELISAs are detecting sheep proteins and antigens, Sheep, a male as a , castrated , ewe , lamb, male as a , ram, sheep , wether |
| Alternative name: |
polyclonal (Immunoglobulin G) to ovine YWHAH / 14-3-3 Eta |
| Alternative technique: |
immunoglobulins |
| Identity: |
12854 |
| Gene: |
YWHAQ |
More about : YWHAQ |
| Long gene name: |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta |
| Synonyms gene name: |
theta , theta polypeptide protein, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein |
| Synonyms: |
HS1 14-3-3 |
| Synonyms name: |
protein tau |
| Locus: |
2p25, 1 |
| Discovery year: |
1999-08-20 |
| GenBank acession: |
AF070556 |
| Entrez gene record: |
10971 |
| Pubmed identfication: |
11080204 |
| RefSeq identity: |
NM_006826 |
| Classification: |
14-3-3 phospho-serine/phospho-threonine binding proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000013848 |