| Alternative name 1: |
Biotin, Clone: MRC OX-34, E-Rosette Receptor, LFA-2, Mab anti-Rat, CD2 |
| Alternative name 2: |
Biotin, Clone: MRC OX-34, E-Rosette Receptor, LFA-2, Mab antibody-Rat, CD2 |
| Alternative name 3: |
Biotin, Clone: MRC OX-34, E-Rosette Receptor, LFA-2, Mab antibody-Rattus norvegicustus norvegicus, CD2 |
| Alternative name 4: |
anti-CD2 LFA-2 E-Rosette Receptor Clone: MRC OX-34 |
| Alternative name 5: |
CD2 LFA-2 E-Rosette Receptor Clone: MRC OX-34 |
| Clonality: |
Monoclonal Antibody |
| Description: |
Amongst the advantages of the monoclonal antibodies are: the fact that while the hybridoma takes a bit longer to be produced, If used correctly and according the protocol, in comparison to the polyclonal antibodies monoclonal antibodies are highly specific to a given epitope and can be used in applications where specific targeting is required, once the line is ready there is virtually an endless supply of these antibodie throughout time with little to no variations in recognition sites of the antigen in different batches, this antibody will provide excellent and reproducible results with guaranteed success for the tested and confirmed applications, This is a monoclonal antibody which is greatly purified and with high binding affinity for the antigen that it is risen against |
| Storage and handling: |
Antibodies in a liquid form can be shipped and stored for a short period of time at +4 degrees Celsius, antibodies that are lyophilized can be transported at ambient temperature and stored for short terms at +4 degrees Celsius, for long term storage (up to one year) 25-50% glycerol or ethylene glycol should be added and then the container has to be stored at -20°, for longer periods - at -20 , C, Generally |
| Advisory: |
For antibodies in a liquid form or reconstituted lyophilized antibodies small amounts of the soultion could be captured on the cap or the walls of the container, Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom, To keep the quality and the affinity of the antibody cycles of freezing and thawing should be avoided |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, Biotin conjugates can be detected by horseradish peroxidase |
| Conjugation: |
Biotinylated |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Rats are used to make rat monoclonal anti mouse antibodies, Rats , There are less rat- than mouse clones however, Monoclonals of this antigen are available in different clones, Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats, genes from rodents , of the genus |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Rattus norvegicus, Mus musculus |
| French translation: |
anticorps |
| Gene target: |
E-Rosette Receptor, LFA-2, MRC OX-34, Monoclonal, CD2 |
| Short name: |
Clone: MRC OX-34, E-Rosette Receptor, LFA-2, Mouse Monoclonal antibody-, CD2 |
| Technique: |
Monoclonals or monoclonal antibodies, mouses, Mouse |
| Host: |
Rat |
| Label: |
Biotin |
| Species: |
Mouses, Rats, Rat |
| Alternative name: |
E-Rosette Receptor, LFA-2, Mouse monoclonal (Antibody to)-Rat, biotinilated, clonality: MRC OX-34, CD2 molecule |
| Alternative technique: |
murine |
| Alternative to gene target: |
CD2 and IDBG-101417 and ENSG00000116824 and 914, CD2 and IDBG-634458 and ENSBTAG00000017256 and 497022, Cd2 and IDBG-179684 and ENSMUSG00000027863 and 12481, Extracellular, LFA-2 and SRBC and T11, protein homodimerization activity, this GO :0001766 and membrane raft polarization and biological process this GO :0004872 and receptor activity and molecular function this GO :0005102 and receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0005911 and cell-cell junction and cellular component this GO :0006915 and apoptotic process and biological process this GO :0007155 and cell adhesion and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007596 and blood coagulation and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0009898 and cytoplasmic side of plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016337 and single organismal cell-cell adhesion and biological process this GO :0030101 and natural killer cell activation and biological process this GO :0030887 and positive regulation of myeloid dendritic cell activation and biological process this GO :0032760 and positive regulation of tumor necrosis factor production and biological process this GO :0034113 and heterotypic cell-cell adhesion and biological process this GO :0042110 and T cell activation and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0045580 and regulation of T cell differentiation and biological process this GO :0046658 and anchored component of plasma membrane and cellular component this GO :0050900 and leukocyte migration and biological process this GO :1902715 and positive regulation of interferon-gamma secretion and biological process this GO :2000484 and positive regulation of interleukin-8 secretion and biological process, this GO :0004872 : receptor activity, this GO :0004872 : receptor activity and also this GO :0005102 : receptor binding and also this GO :0005515 : protein binding and also this GO :0042803 : protein homodimerization activity, this GO :0005102 : receptor binding, this GO :0005515 : protein binding, this GO :0042803 : protein homodimerization activity, CD2 molecule |
| Identity: |
7203 |
| Gene: |
CD200 |
More about : CD200 |
| Long gene name: |
CD200 molecule |
| Synonyms gene: |
MOX1 MOX2 |
| Synonyms gene name: |
antigen identified by monoclonal antibody MRC OX-2 CD200 antigen |
| Synonyms: |
MRC OX-2 |
| Locus: |
3q13, 2 |
| Discovery year: |
2001-06-22 |
| Entrez gene record: |
4345 |
| Classification: |
Immunoglobulin like domain containing CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000159248 |