| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Prion protein PrP |
| Specificity: |
This antibody reacts specifically with Prion protein PrP |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Major prion protein |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
AltPrp, Alternative splicing results in multiple transcript variants, An overlapping open reading frame has been found for this gene that encodes a smaller, Gerstmann-Straussler disease, Huntington disease-like 1, Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease, Oct 2012], The encoded protein contains a highly unstable region of five tandem octapeptide repeats, This gene is found on chromosome 20, [provided by RefSeq, and kuru, approximately 20 kbp upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene, fatal familial insomnia, structurally unrelated protein, The protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
CD230 PRP AltPrP PRNP |
| Also known as: |
Prion protein PrP Polyclonal Antibody |
| Other name: |
Anti-Prion protein PrP Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
Prion protein PrP |
| Short name: |
Anti-Prion protein PrP (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Prion protein PrP (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
1988 |
| Gene: |
CJD |
More about : CJD |
| Long gene name: |
prion protein |
| Synonyms gene: |
PRIP GSS |
| Synonyms gene name: |
prion protein (p27-30) |
| Synonyms name: |
Creutzfeldt-Jakob disease Gerstmann-Strausler-Scheinker syndrome fatal familial insomnia p27-30 |
| Locus: |
20p13 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
M13899 |
| Entrez gene record: |
5621 |
| RefSeq identity: |
NM_000311 |
| Classification: |
CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000031786 |
| Locus Specific Databases: |
Prion Protein/CJD database |