| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Prion protein PrP/CD230 |
| Specificity: |
This antibody reacts specifically with Prion protein PrP/CD230 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Prion protein PrP/CD230 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Isoform 2 may act as a growth suppressor by arresting the cell cycle at the G0/G1 phase, May be required for neuronal myelin sheath maintenance, May play a role in iron uptake and iron homeostasis (By similarity), May play a role in neuronal development and synaptic plasticity, Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro), The function of PrP is still under debate |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
CD230 PRP AltPrP |
| Also known as: |
Prion protein PrP/CD230 Antibody |
| Other name: |
Anti-Prion protein PrP/CD230 |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
Prion protein PrP/CD230 |
| Short name: |
Fluor 594, Anti-Prion protein PrP/CD230 |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Prion protein PrP/CD230 |
| Identity: |
9449 |
| Gene: |
PRNP |
More about : PRNP |
| Long gene name: |
prion protein |
| Synonyms gene: |
PRIP GSS CJD |
| Synonyms gene name: |
prion protein (p27-30) |
| Synonyms name: |
Creutzfeldt-Jakob disease Gerstmann-Strausler-Scheinker syndrome fatal familial insomnia p27-30 |
| Locus: |
20p13 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
M13899 |
| Entrez gene record: |
5621 |
| RefSeq identity: |
NM_000311 |
| Classification: |
CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000031786 |
| Locus Specific Databases: |
Prion Protein/CJD database |