| known also as: |
TOP2, TOP2A, TP2A), Anti-Topoisomerase II (DNA) alpha (DNA Topoisomerase 2 alpha |
| known also as: |
TOP2, TOP2A, TP2A), Topoisomerase II (DNA) alpha (DNA Topoisomerase 2 alpha |
| known also as: |
TOP2, TOP2A, TP2A), Topoisomerase II (DNA) alpha (DNA Topoisomerase 2 alpha |
| known also as: |
Topoisomerase II |
| known also as: |
TOP2, TOP2A, TP2A), Anti -Topoisomerase II (DNA) alpha (DNA Topoisomerase 2 alpha |
| Other names: |
N/A, topoisomerase II |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Host organism: |
Source: Human, Host: Rabbit |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
Other species not tested, Species Crossreactivity: Human |
| Purification method: |
Affinity Purified by immunoaffinity chromatography |
| Form/Appearance: |
0, 0, pH 7, 1% BSA, 1% sodium azide, 2, Supplied as a liquid in TBS |
| Storage and shipping: |
Aliquots are stable for at least 3 months productone should be stored at -20 degrees Celsius, For long-term storage and to avoid repeated freezing and thawing, For maximum recovery of product, Further dilutions can be made in assay buffer, add sterile glycerol (40-50%), aliquot and For optimal long term storage, centrifuge the original vial after thawing and prior to removing the cap, productone should be kept at -20 degrees Celsius, Store at 4 degrees Celsius for short term storage |
| Tested for:: |
Immunoprecipitation (IP), Western Blot (WB) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Gene target: |
TOP2, TOP2A, TP2A), Topoisomerase II (DNA) alpha (DNA Topoisomerase 2 alpha |
| Short name: |
TOP2, TOP2A, TP2A), Topoisomerase II (DNA) alpha (DNA Topoisomerase 2 alpha |
| Alternative name: |
TOP2, TP2A), topoisomerase (Desoxyribonucleic acid) II alpha 170kDa, Topoisomerase II (Desoxyribonucleic acid) a (Desoxyribonucleic acid Topoisomerase 2 a |
| Alternative to gene target: |
DNA binding, TOP2 and TP2A, TOP2A and IDBG-47552 and ENSG00000131747 and 7153, TOP2A and IDBG-639659 and ENSBTAG00000019262 and 787696, Top2a and IDBG-210864 and ENSMUSG00000020914 and 21973, bending, bending and also this GO :0019899 : enzyme binding and also this GO :0042803 : protein homodimerization activity and also this GO :0042826 : histone deacetylase binding and also this GO :0043130 : ubiquitin binding and also this GO :0044822 : poly(A) RNA binding and also this GO :0046982 : protein heterodimerization activity, bending and molecular function this GO :0009330 and DNA topoisomerase complex (ATP-hydrolyzing) and cellular component this GO :0019035 and viral integration complex and cellular component this GO :0019899 and enzyme binding and molecular function this GO :0030261 and chromosome condensation and biological process this GO :0030263 and apoptotic chromosome condensation and biological process this GO :0040016 and embryonic cleavage and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0042826 and histone deacetylase binding and molecular function this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043130 and ubiquitin binding and molecular function this GO :0043234 and protein complex and cellular component this GO :0044774 and mitotic DNA integrity checkpoint and biological process this GO :0044822 and poly(A) RNA binding and molecular function this GO :0045070 and positive regulation of viral genome replication and biological process this GO :0045870 and positive regulation of retroviral genome replication and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046982 and protein heterodimerization activity and molecular function this GO :0048015 and phosphatidylinositol-mediated signaling and biological process, nuclei, this GO :0000228 and nuclear chromosome and cellular component this GO :0000278 and mitotic cell cycle and biological process this GO :0000287 and magnesium ion binding and molecular function this GO :0000712 and resolution of meiotic recombination intermediates and biological process this GO :0000793 and condensed chromosome and cellular component this GO :0000819 and sister chromatid segregation and biological process this GO :0002244 and hematopoietic progenitor cell differentiation and biological process this GO :0003677 and DNA binding and molecular function this GO :0003682 and chromatin binding and molecular function this GO :0003918 and DNA topoisomerase (ATP-hydrolyzing) activity and molecular function this GO :0005080 and protein kinase C binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005730 and nucleolus and cellular component this GO :0005814 and centriole and cellular component this GO :0006200 and ATP catabolic process and biological process this GO :0006260 and DNA replication and biological process this GO :0006265 and DNA topological change and biological process this GO :0006266 and DNA ligation and biological process this GO :0006268 and DNA unwinding involved in DNA replication and biological process this GO :0006281 and DNA repair and biological process this GO :0006312 and mitotic recombination and biological process this GO :0006974 and cellular response to DNA damage stimulus and biological process this GO :0007059 and chromosome segregation and biological process this GO :0008022 and protein C-terminus binding and molecular function this GO :0008094 and DNA-dependent ATPase activity and molecular function this GO :0008144 and drug binding and molecular function this GO :0008301 and DNA binding, this GO :0000287 : magnesium ion binding, this GO :0000287 : magnesium ion binding and also this GO :0003677 : DNA binding and also this GO :0003682 : chromatin binding and also this GO :0003918 : DNA topoisomerase (ATP-hydrolyzing) activity and also this GO :0005080 : protein kinase C binding and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0008022 : protein C-terminus binding and also this GO :0008094 : DNA-dependent ATPase activity and also this GO :0008144 : drug binding and also this GO :0008301 : DNA binding, this GO :0003677 : DNA binding, this GO :0003682 : chromatin binding, this GO :0003918 : DNA topoisomerase (ATP-hydrolyzing) activity, this GO :0005080 : protein kinase C binding, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0008022 : protein C-terminus binding, this GO :0008094 : DNA-dependent ATPase activity, this GO :0008144 : drug binding, this GO :0008301 : DNA binding, this GO :0019899 : enzyme binding, this GO :0042803 : protein homodimerization activity, this GO :0042826 : histone deacetylase binding, this GO :0043130 : ubiquitin binding, this GO :0044822 : poly(A) RNA binding, this GO :0046982 : protein heterodimerization activity, topoisomerase (DNA) II alpha 170kDa |
| Identity: |
11989 |
| Gene: |
TOP2A |
More about : TOP2A |
| Long gene name: |
topoisomerase (DNA) II alpha |
| Synonyms gene: |
TOP2 |
| Synonyms gene name: |
topoisomerase (DNA) II alpha 170kDa |
| Locus: |
17q21, 2 |
| Discovery year: |
1989-03-23 |
| Entrez gene record: |
7153 |
| Classification: |
Topoisomerases |
| Havana BLAST/BLAT: |
OTTHUMG00000155008 |