| Also known as: |
CD28 |
| Other names: |
N/A, N/A, T-cell-specific surface glycoprotein CD28, T-cell-specific surface glycoprotein CD28, T-cell-specific surface glycoprotein CD28 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CD28 |
| Other gene names: |
CD28, N/A, N/A, CD28 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
Mouse IgG1 |
| Clone: |
JJ319 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Rat (Rattus norvegicus) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, receptor for B7 family) (Rat CD28), CD28 (Tp44 |
| Form/Appearance: |
(Purified from Bioreactor supernatant via Protein G Chromatography)), 0, 02% NaN3 and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/ml, FITC (FITC conjugated Ig buffered in PBS |
| Concentration: |
1 miligram per 1 mililiter, Antibody Concentration: 0 |
| Storage and shipping: |
Avoid freeze/thaw cycles, Avoid prolonged exposure to light, For long term storage, aliquot and freeze unused portion the antibody should be stored at -20 degrees Celsius, in volumes appropriate for single usage, Store the antibody at +4 degrees Celsius |
| Tested applications:: |
Immunohistochemistry (IHC) |
| Properties: |
FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, MBS mono FITC is highly sensitive to pH extremes, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, This MBS mono Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS |
| Conjugation: |
Anti-FITC Antibody |
| About: |
Rats , There are less rat- than mouse clones however, Rats are used to make rat monoclonal anti mouse antibodies, Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats, genes from rodents , of the genus |
| Latin name: |
Rattus norvegicus |
| Gene target: |
CD28 JJ319) IgG1) |
| Short name: |
Anti- CD28 FITC (Clone JJ319) (mouse IgG1) |
| Technique: |
Fluorescein, FITC |
| Host: |
Rat |
| Isotype: |
IgG1 |
| Label: |
FITC |
| Species: |
Rats, Rat |
| Alternative name: |
antibody to-Rat CD28 molecule fluorecein (clonality JJ319) (mouse IgG1) |
| Alternative technique: |
fluorescine |
| Alternative to gene target: |
CD28 and IDBG-643371 and ENSBTAG00000007445 and 281050, CD28 and IDBG-79183 and ENSG00000178562 and 940, Cd28 and IDBG-159608 and ENSMUSG00000026012 and 12487, Cell surfaces, Tp44, identical protein binding, this GO :0001772 and immunological synapse and cellular component this GO :0002020 and protease binding and molecular function this GO :0002863 and positive regulation of inflammatory response to antigenic stimulus and biological process this GO :0005070 and SH3/SH2 adaptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006959 and humoral immune response and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007173 and epidermal growth factor receptor signaling pathway and biological process this GO :0008543 and fibroblast growth factor receptor signaling pathway and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0009967 and positive regulation of signal transduction and biological process this GO :0015026 and coreceptor activity and molecular function this GO :0016032 and viral process and biological process this GO :0031295 and T cell costimulation and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0042089 and cytokine biosynthetic process and biological process this GO :0042102 and positive regulation of T cell proliferation and biological process this GO :0042802 and identical protein binding and molecular function this GO :0045060 and negative thymic T cell selection and biological process this GO :0045066 and regulatory T cell differentiation and biological process this GO :0045070 and positive regulation of viral genome replication and biological process this GO :0045086 and positive regulation of interleukin-2 biosynthetic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045727 and positive regulation of translation and biological process this GO :0045840 and positive regulation of mitosis and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046641 and positive regulation of alpha-beta T cell proliferation and biological process this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0048015 and phosphatidylinositol-mediated signaling and biological process this GO :0048304 and positive regulation of isotype switching to IgG isotypes and biological process this GO :0050690 and regulation of defense response to virus by virus and biological process this GO :0050852 and T cell receptor signaling pathway and biological process this GO :0097190 and apoptotic signaling pathway and biological process, this GO :0002020 : protease binding, this GO :0002020 : protease binding and also this GO :0005070 : SH3/SH2 adaptor activity and also this GO :0005515 : protein binding and also this GO :0015026 : coreceptor activity and also this GO :0042802 : identical protein binding, this GO :0005070 : SH3/SH2 adaptor activity, this GO :0005515 : protein binding, this GO :0015026 : coreceptor activity, this GO :0042802 : identical protein binding, CD28 molecule |
| Identity: |
1653 |
| Gene: |
CD28 |
More about : CD28 |
| Long gene name: |
CD28 molecule |
| Synonyms gene name: |
CD28 antigen (Tp44) |
| Synonyms name: |
T-cell-specific surface glycoprotein |
| Locus: |
2q33, 2 |
| Discovery year: |
1988-05-11 |
| GenBank acession: |
J02988 |
| Entrez gene record: |
940 |
| Pubmed identfication: |
1355979 |
| RefSeq identity: |
NM_006139 |
| Classification: |
CD molecules V-set domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000132878 |