| Also known as: |
MUC4 |
| Other names: |
ASGP, ASGP-1, Ascites sialoglycoprotein, GRCh37, Mucin-4, Pancreatic adenocarcinoma mucin, Testis mucin, Tracheobronchial mucinCleaved into the following 2 chains:Mucin-4 alpha chainAlternative name(s):Ascites sialoglycoprotein 1, ascites sialoglycoprotein, cell surface associated, mucin 4, mucin 4, mucin-4, pancreatic adenocarcinoma mucin, testis mucin, tracheobronchial, tracheobronchial mucin, Homo sapiens chromosome 3, p13 Primary Assembly |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
MUC4 |
| Other gene names: |
ASGP, ASGP, ASGP-1, ASGP-2, HSA276359, MUC-4, MUC-4, MUC4, MUC4 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
1G8 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, Rat (Rattus norvegicus), the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
In abnormal tissues, In normal tissues, Lung adenocarcinoma and ovarian mucinous adenocarcinoma also demonstrated positive staining, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, Species cross-reactivity: human, This antibody exhibits strong positive staining in colon polyps (3/3 specimens tested), This particular antibody might cross react with speacies outside of the listed ones, and gastric adenocarcinoma (4/5), and the endothelial cells of small blood vessels and capillaries, colon, colon carcinoma (4/4), stains stomach, Recognizes rat MUC4 |
| Purification method: |
Purified |
| Form/Appearance: |
0, 1% BSA, Sourced in Ascites, pH 7, 1% sodium azide, 4, PBS |
| Concentration: |
1 miligram per 1 mililiter |
| Storage and shipping: |
Cycles of freezing/defrosting can damage the peptide chains of the antibodies thus reducing the activity, Short term storage of the antibody can be done at +4 degrees Celsius, keep the antibody at -20 degrees Celsius, For long term storage |
| Tested applications:: |
IHC - Frozen), Immunohistochemistry (IHC - Paraffin |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Rats are used to make rat monoclonal anti mouse antibodies, Rats , There are less rat- than mouse clones however, Monoclonals of this antigen are available in different clones, Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats, genes from rodents , of the genus |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Rattus norvegicus, Mus musculus |
| Gene target: |
Monoclonal [ 1G8] (IgG1) MUC4 |
| Short name: |
Mouse Monoclonal [clone 1G8] (IgG1) MUC4 Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Host: |
Rat |
| Isotype: |
IgG1 |
| Species: |
Mouses, Rats, Rat |
| Alternative name: |
cellular surface associated (Antibody to), Mouse monoclonal [clonality 1G8] (IgG1) to Rat mucin 4 |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
ASGP and HSA276359 and MUC-4, Extracellular, MUC4 and IDBG-633795 and ENSBTAG00000014721 and, MUC4 and IDBG-70699 and ENSG00000145113 and 4585, Muc4 and IDBG-250337 and ENSMUSG00000079620 and 140474, cell surface associated, extracellular matrix constituent, lubricant activity, lubricant activity, lubricant activity and molecular function this GO :0030277 and maintenance of gastrointestinal epithelium and biological process this GO :0043687 and post-translational protein modification and biological process this GO :0044267 and cellular protein metabolic process and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0002244 and hematopoietic progenitor cell differentiation and biological process this GO :0005176 and ErbB-2 class receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005578 and proteinaceous extracellular matrix and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005796 and this GO lgi lumen and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007160 and cell-matrix adhesion and biological process this GO :0016020 and membrane and cellular component this GO :0016266 and O-glycan processing and biological process this GO :0030197 and extracellular matrix constituent, this GO :0005176 : ErbB-2 class receptor binding, this GO :0005176 : ErbB-2 class receptor binding and also this GO :0005515 : protein binding and also this GO :0030197 : extracellular matrix constituent, this GO :0005515 : protein binding, this GO :0030197 : extracellular matrix constituent, mucin 4 |
| Identity: |
7514 |
| Gene: |
MUC4 |
More about : MUC4 |
| Long gene name: |
cell surface associated , mucin 4 |
| Synonyms gene name: |
mucin 4, tracheobronchial |
| Locus: |
3q29 |
| Discovery year: |
1991-05-22 |
| GenBank acession: |
AJ276359 |
| Entrez gene record: |
4585 |
| Pubmed identfication: |
1673336 |
| RefSeq identity: |
NM_018406 |
| Classification: |
Mucins |
| Havana BLAST/BLAT: |
OTTHUMG00000151827 |