| known also as: |
Anti-Rabbit Polyclonal to Rat GCLC |
| known also as: |
Rabbit PAb to Rat GCLC |
| known also as: |
Lapin Polyclonal to Rattus norvegicus GCLC |
| known also as: |
GCLC |
| known also as: |
GCL, GCLC, GCS, GCS heavy chain, GLCL, GLCLC, Gamma-ECS, Rat GCLC, Anti-GCLC Antibody (aa295-313) IHC-plus |
| Other names: |
GCS heavy chain, GCS heavy chain, Gamma-ECS, Gamma-glutamylcysteine synthetase, Glutamate--cysteine ligase catalytic subunit, catalytic subunit, gamma-ECS, gamma-glutamylcysteine synthetase, glutamate--cysteine ligase catalytic subunit, glutamate-cysteine ligase, glutamate--cysteine ligase catalytic subunit isoform a |
| Gene name: |
GCLC |
| Other gene names: |
GCL, GCLC, GCS, GLCL, GLCL, GLCLC, GLCLC, GCLC |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Human, Monkey, Mouse, Rat, Bovine |
| Specificity and cross-reactivity: |
Cross-reacts weakly with bovine, Species cross-reactivity: human, monkey and mouse, Recognizes the heavy subunit of rat GCS |
| Purification method: |
Protein A Purified |
| Form/Appearance: |
0, 0, pH 7, 09% sodium azide, 2% BSA, 4, PBS |
| Concentration: |
1 miligram per 1 mililiter |
| Storage and shipping: |
Avoid repeated freezing and thawing, or Store productone at -20 degrees Celsius, +Store productone at +4 degrees Celsius |
| Tested for:: |
ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| About: |
Rats , There are less rat- than mouse clones however, Rats are used to make rat monoclonal anti mouse antibodies, Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats, genes from rodents , of the genus |
| Latin name: |
Rattus norvegicus |
| Gene target: |
GCLC |
| Short name: |
Anti- GCLC |
| Host: |
Rat |
| Species: |
Rats, Rat |
| Alternative name: |
catalytic subunit, antibody to-Rat glutamate-cysteine ligase |
| Alternative to gene target: |
Cytoplasm, DNA-templated and biological process this GO :0046685 and response to arsenic-containing substance and biological process this GO :0046982 and protein heterodimerization activity and molecular function this GO :0050662 and coenzyme binding and molecular function this GO :0050880 and regulation of blood vessel size and biological process this GO :0051409 and response to nitrosative stress and biological process this GO :0051900 and regulation of mitochondrial depolarization and biological process this GO :1901687 and glutathione derivative biosynthetic process and biological process this GO :2001237 and negative regulation of extrinsic apoptotic signaling pathway and biological process, GCL and GCS and GLCL and GLCLC, GCLC and IDBG-628748 and ENSBTAG00000015571 and 512468, GCLC and IDBG-91041 and ENSG00000001084 and 102724876, Gclc and IDBG-186028 and ENSMUSG00000032350 and 14629, catalytic subunit, coenzyme binding, this GO :0000096 and sulfur amino acid metabolic process and biological process this GO :0000287 and magnesium ion binding and molecular function this GO :0004357 and glutamate-cysteine ligase activity and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006534 and cysteine metabolic process and biological process this GO :0006536 and glutamate metabolic process and biological process this GO :0006749 and glutathione metabolic process and biological process this GO :0006750 and glutathione biosynthetic process and biological process this GO :0006805 and xenobiotic metabolic process and biological process this GO :0006979 and response to oxidative stress and biological process this GO :0008637 and apoptotic mitochondrial changes and biological process this GO :0009408 and response to heat and biological process this GO :0009410 and response to xenobiotic stimulus and biological process this GO :0009725 and response to hormone and biological process this GO :0016595 and glutamate binding and molecular function this GO :0017109 and glutamate-cysteine ligase complex and cellular component this GO :0019852 and L-ascorbic acid metabolic process and biological process this GO :0031397 and negative regulation of protein ubiquitination and biological process this GO :0032436 and positive regulation of proteasomal ubiquitin-dependent protein catabolic process and biological process this GO :0034641 and cellular nitrogen compound metabolic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043524 and negative regulation of neuron apoptotic process and biological process this GO :0043531 and ADP binding and molecular function this GO :0044281 and small molecule metabolic process and biological process this GO :0045454 and cell redox homeostasis and biological process this GO :0045892 and negative regulation of transcription, this GO :0000287 : magnesium ion binding, this GO :0000287 : magnesium ion binding and also this GO :0004357 : glutamate-cysteine ligase activity and also this GO :0005524 : ATP binding and also this GO :0016595 : glutamate binding and also this GO :0043531 : ADP binding and also this GO :0046982 : protein heterodimerization activity and also this GO :0050662 : coenzyme binding, this GO :0004357 : glutamate-cysteine ligase activity, this GO :0005524 : ATP binding, this GO :0016595 : glutamate binding, this GO :0043531 : ADP binding, this GO :0046982 : protein heterodimerization activity, this GO :0050662 : coenzyme binding, 2729, glutamate-cysteine ligase |
| Identity: |
4311 |
| Gene: |
GCLC |
More about : GCLC |
| Long gene name: |
glutamate-cysteine ligase catalytic subunit |
| Synonyms gene: |
GLCLC GLCL |
| Synonyms gene name: |
catalytic subunit , glutamate-cysteine ligase |
| Synonyms: |
GCS |
| Locus: |
6p12, 1 |
| Discovery year: |
1993-11-24 |
| GenBank acession: |
M90656 |
| Entrez gene record: |
2729 |
| Pubmed identfication: |
1350904 |
| Havana BLAST/BLAT: |
OTTHUMG00000160220 |