| Also known as: |
GFAP |
| Other names: |
Glial fibrillary acidic protein, N/A, glial fibrillary acidic protein, glial fibrillary acidic protein, glial fibrillary acidic protein isoform 1 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
GFAP |
| Other gene names: |
GFAP, GFAP, N/A, GFAP |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2b |
| Clone: |
GF-01 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, Human (Homo sapiens), Pig, the reactivity of the antibody may extend to other species which are not listed hereby, Cat |
| Specificity and cross-reactivity: |
GFAP is the principal marker of astroglial cells in the central nervous system, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The GFAP protein runs on gels at ~55 kD protein, This particular antibody might cross react with speacies outside of the listed ones, it is specifically expressed in satellite cells in peripheral ganglia and in non myelinating Schwann cells in peripheral nerves, usually associated with lower Mw bands which are thought to be proteolytic fragments and alternate transcripts from the single gene, Reacts with GFAP molecules |
| Purification method: |
Protein A Purified |
| Form/Appearance: |
15 mM sodium azide, approx, pH 7, 4, PBS |
| Storage and shipping: |
For long term storage aliquot and keep the antibody at -20 degrees Celsius, Freeze-thaw cycles should be avoided in order to retain the activity of the antibody, Store at +4 degrees Celsius for short term storage |
| Tested applications:: |
Immunocytochemistry (ICC), Immunoprecipitation (IP), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Pigs and the smaller guinea pigs are frequent used as models for humans, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ GF-01] (IgG2b) GFAP |
| Short name: |
Mouse Monoclonal [clone GF-01] (IgG2b) GFAP Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG2b |
| Species: |
Mouses, Pigs and Guinea pigs, Pig |
| Alternative name: |
Mouse monoclonal [clonality GF-01] (IgG2b) to swine GFAP (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
4235 |
| Gene: |
GFAP |
More about : GFAP |
| Long gene name: |
glial fibrillary acidic protein |
| Synonyms: |
FLJ45472 |
| Synonyms name: |
intermediate filament protein |
| Locus: |
17q21, 31 |
| Discovery year: |
1989-12-07 |
| GenBank acession: |
S40719 |
| Entrez gene record: |
2670 |
| Pubmed identfication: |
9693047 |
| RefSeq identity: |
NM_002055 |
| Classification: |
Intermediate filaments Type III |
| Havana BLAST/BLAT: |
OTTHUMG00000179866 |