| Alternative name 1: |
115kD, C-terminal, Clone: A1-14-16, IH/WB/IP, L-JAD, Mab anti-Human, Mouse, paraffin, JAK3 |
| Alternative name 2: |
115kD, C-terminal, Clone: A1-14-16, IH/WB/IP, L-JAD, Mab antibody-Human, Mouse, paraffin, JAK3 |
| Alternative name 3: |
115kD, C-terminal, Clone: A1-14-16, IH/WB/IP, L-JAD, Mab antibody-Homo sapiens, Mus musculus, paraffin, JAK3 |
| Alternative name 4: |
anti-JAK3 L-JAD C-terminal 115kD Clone: A1-14-16 |
| Alternative name 5: |
JAK3 L-JAD C-terminal 115kD Clone: A1-14-16 |
| Clonality: |
Monoclonal Antibody |
| Description: |
Amongst the advantages of the monoclonal antibodies are: the fact that while the hybridoma takes a bit longer to be produced, If used correctly and according the protocol, in comparison to the polyclonal antibodies monoclonal antibodies are highly specific to a given epitope and can be used in applications where specific targeting is required, once the line is ready there is virtually an endless supply of these antibodie throughout time with little to no variations in recognition sites of the antigen in different batches, this antibody will provide excellent and reproducible results with guaranteed success for the tested and confirmed applications, This is a monoclonal antibody which is greatly purified and with high binding affinity for the antigen that it is risen against |
| Storage and handling: |
Antibodies in a liquid form can be shipped and stored for a short period of time at +4 degrees Celsius, antibodies that are lyophilized can be transported at ambient temperature and stored for short terms at +4 degrees Celsius, for long term storage (up to one year) 25-50% glycerol or ethylene glycol should be added and then the container has to be stored at -20°, for longer periods - at -20 , C, Generally |
| Advisory: |
For antibodies in a liquid form or reconstituted lyophilized antibodies small amounts of the soultion could be captured on the cap or the walls of the container, Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom, To keep the quality and the affinity of the antibody cycles of freezing and thawing should be avoided |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, Homo sapiens sapiens), Human proteins, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| French translation: |
anticorps |
| Gene target: |
115kD, A1-14-16, IH/ /IP, L-JAD, Monoclonal paraffin, JAK3 |
| Short name: |
115kD, C-terminal, Clone: A1-14-16, IH/ /IP, L-JAD, Mouse Monoclonal antibody- Mouse, paraffin, JAK3 |
| Technique: |
Monoclonals or monoclonal antibodies, mouses, paraffin |
| Species: |
Humans, Mouses, Mouse |
| Alternative name: |
115kD, C-terminal, IH/Western Blot/IP, L-JAD, Mouse, Mouse monoclonal (Antibody to)-H, clonality: A1-14-16, paraffin, sapiens, Janus kinase 3 |
| Alternative technique: |
murine |
| Alternative to gene target: |
BT, JAK-3 and JAK3_HUMAN and JAKL and L-JAK and LJAK, JAK3 and IDBG-37201 and ENSG00000105639 and 3718, Jak3 and IDBG-166648 and ENSMUSG00000031805 and 16453, Plasma membranes, this GO :0002731 and negative regulation of dendritic cell cytokine production and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0004715 and non-membrane spanning protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005829 and cytosol and cellular component this GO :0005856 and cytoskeleton and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0007167 and enzyme linked receptor protein signaling pathway and biological process this GO :0007260 and tyrosine phosphorylation of STAT protein and biological process this GO :0007262 and STAT protein import into nucleus and biological process this GO :0012505 and endomembrane system and cellular component this GO :0016020 and membrane and cellular component this GO :0016772 and transferase activity, this GO :0004672 : protein kinase activity, this GO :0004672 : protein kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0004715 : non-membrane spanning protein tyrosine kinase activity and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0016772 : transferase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0004715 : non-membrane spanning protein tyrosine kinase activity, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0016772 : transferase activity, this GO :0019903 : protein phosphatase binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0019903 : protein phosphatase binding, transferring phosphorus-containing groups and molecular function this GO :0018108 and peptidyl-tyrosine phosphorylation and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0019903 and protein phosphatase binding and molecular function this GO :0030183 and B cell differentiation and biological process this GO :0032693 and negative regulation of interleukin-10 production and biological process this GO :0032695 and negative regulation of interleukin-12 production and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0035771 and interleukin-4-mediated signaling pathway and biological process this GO :0043029 and T cell homeostasis and biological process this GO :0045087 and innate immune response and biological process this GO :0045221 and negative regulation of FasL biosynthetic process and biological process this GO :0045626 and negative regulation of T-helper 1 cell differentiation and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0050868 and negative regulation of T cell activation and biological process this GO :0060397 and JAK-STAT cascade involved in growth hormone signaling pathway and biological process this GO :0070232 and regulation of T cell apoptotic process and biological process this GO :0070244 and negative regulation of thymocyte apoptotic process and biological process this GO :0070669 and response to interleukin-2 and biological process this GO :0070670 and response to interleukin-4 and biological process this GO :0070672 and response to interleukin-15 and biological process this GO :0071104 and response to interleukin-9 and biological process this GO :2000670 and positive regulation of dendritic cell apoptotic process and biological process this GO :2001241 and positive regulation of extrinsic apoptotic signaling pathway in absence of ligand and biological process, 44422 and IDBG-641863 and ENSBTAG00000020904 and 538276, Janus kinase 3 |
| Identity: |
6193 |
| Gene: |
JAK3 |
More about : JAK3 |
| Long gene name: |
Janus kinase 3 |
| Synonyms: |
L-JAK JAKL LJAK JAK3_HUMAN JAK-3 |
| Synonyms name: |
tyrosine-protein kinase JAK3 leukocyte Janus kinase |
| Locus: |
19p13, 11 |
| Discovery year: |
1994-12-19 |
| GenBank acession: |
U31601 |
| Entrez gene record: |
3718 |
| Pubmed identfication: |
8921370 9226382 |
| RefSeq identity: |
NM_000215 |
| Havana BLAST/BLAT: |
OTTHUMG00000165648 |
| Locus Specific Databases: |
JAK3base: Mutation registry for autosomal recessive severe combined JAK3 deficiency LRG_77 |