| Alternative name 1: |
APC conj, Clone: HI40a, Mab anti-, CD40 |
| Alternative name 2: |
APC conj, Clone: HI40a, Mab antibody-, CD40 |
| Alternative name 3: |
APC conj, Clone: HI40a, Mab antibody-, CD40 |
| Alternative name 4: |
anti-CD40 Clone: HI40a |
| Alternative name 5: |
CD40 Clone: HI40a |
| Clonality: |
Monoclonal Antibody |
| Description: |
Amongst the advantages of the monoclonal antibodies are: the fact that while the hybridoma takes a bit longer to be produced, If used correctly and according the protocol, in comparison to the polyclonal antibodies monoclonal antibodies are highly specific to a given epitope and can be used in applications where specific targeting is required, once the line is ready there is virtually an endless supply of these antibodie throughout time with little to no variations in recognition sites of the antigen in different batches, this antibody will provide excellent and reproducible results with guaranteed success for the tested and confirmed applications, This is a monoclonal antibody which is greatly purified and with high binding affinity for the antigen that it is risen against |
| Storage and handling: |
Antibodies in a liquid form can be shipped and stored for a short period of time at +4 degrees Celsius, antibodies that are lyophilized can be transported at ambient temperature and stored for short terms at +4 degrees Celsius, for long term storage (up to one year) 25-50% glycerol or ethylene glycol should be added and then the container has to be stored at -20°, for longer periods - at -20 , C, Generally |
| Advisory: |
For antibodies in a liquid form or reconstituted lyophilized antibodies small amounts of the soultion could be captured on the cap or the walls of the container, Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom, To keep the quality and the affinity of the antibody cycles of freezing and thawing should be avoided |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| French translation: |
anticorps |
| Gene target: |
APC conj, Monoclonal HI40a, CD40 |
| Short name: |
APC conj, Mouse Monoclonal antibody- Clone: HI40a, CD40 |
| Technique: |
Monoclonals or monoclonal antibodies, mouses, Mouse |
| Label: |
APC |
| Species: |
Mouses, Mouse |
| Alternative name: |
Mouse monoclonal (Antibody to)-, adenomatous polyposis coli conj, clonality: HI40a, tumor necrosis factor receptor superfamily member 5, CD40 molecule |
| Alternative technique: |
murine |
| Alternative to gene target: |
APC and IDBG-37007 and ENSG00000134982 and 324, Apc and IDBG-134573 and ENSMUSG00000005871 and 11789, BT, BT, BTPS2 and DP2 and DP2, Bp50 and CDW40 and p50 and TNFRSF5, CD40 and IDBG-78904 and ENSG00000101017 and 958, CD40 molecule, Cd40 and IDBG-212533 and ENSMUSG00000017652 and 21939, Extracellular, TNF receptor superfamily member 5, microtubule plus-end binding, nuclei, this GO :0000281 and mitotic cytokinesis and biological process this GO :0000776 and kinetochore and cellular component this GO :0001822 and kidney development and biological process this GO :0001942 and hair follicle development and biological process this GO :0005488 and binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005813 and centrosome and cellular component this GO :0005829 and cytosol and cellular component this GO :0005881 and cytoplasmic microtubule and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005913 and cell-cell adherens junction and cellular component this GO :0005923 and tight junction and cellular component this GO :0006461 and protein complex assembly and biological process this GO :0006915 and apoptotic process and biological process this GO :0006921 and cellular component disassembly involved in execution phase of apoptosis and biological process this GO :0006974 and cellular response to DNA damage stimulus and biological process this GO :0007026 and negative regulation of microtubule depolymerization and biological process this GO :0007050 and cell cycle arrest and biological process this GO :0007091 and metaphase/anaphase transition of mitotic cell cycle and biological process this GO :0007094 and mitotic spindle assembly checkpoint and biological process this GO :0007155 and cell adhesion and biological process this GO :0007389 and pattern specification process and biological process this GO :0007409 and axonogenesis and biological process this GO :0008013 and beta-catenin binding and molecular function this GO :0008017 and microtubule binding and molecular function this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0009798 and axis specification and biological process this GO :0009952 and anterior/posterior pattern specification and biological process this GO :0009953 and dorsal/ventral pattern formation and biological process this GO :0009954 and proximal/distal pattern formation and biological process this GO :0016055 and Wnt signaling pathway and biological process this GO :0016328 and lateral plasma membrane and cellular component this GO :0016477 and cell migration and biological process this GO :0019827 and stem cell maintenance and biological process this GO :0019887 and protein kinase regulator activity and molecular function this GO :0019901 and protein kinase binding and molecular function this GO :0030027 and lamellipodium and cellular component this GO :0030178 and negative regulation of Wnt signaling pathway and biological process this GO :0030334 and regulation of cell migration and biological process this GO :0030335 and positive regulation of cell migration and biological process this GO :0030424 and axon and cellular component this GO :0030426 and growth cone and cellular component this GO :0030856 and regulation of epithelial cell differentiation and biological process this GO :0030858 and positive regulation of epithelial cell differentiation and biological process this GO :0030877 and beta-catenin destruction complex and cellular component this GO :0031116 and positive regulation of microtubule polymerization and biological process this GO :0031122 and cytoplasmic microtubule organization and biological process this GO :0031253 and cell projection membrane and cellular component this GO :0031274 and positive regulation of pseudopodium assembly and biological process this GO :0032587 and ruffle membrane and cellular component this GO :0032886 and regulation of microtubule-based process and biological process this GO :0033077 and T cell differentiation in thymus and biological process this GO :0035019 and somatic stem cell maintenance and biological process this GO :0035371 and microtubule plus-end and cellular component this GO :0042483 and negative regulation of odontogenesis and biological process this GO :0042995 and cell projection and cellular component this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043409 and negative regulation of MAPK cascade and biological process this GO :0043588 and skin development and biological process this GO :0044295 and axonal growth cone and cellular component this GO :0044336 and canonical Wnt signaling pathway involved in negative regulation of apoptotic process and biological process this GO :0044337 and canonical Wnt signaling pathway involved in positive regulation of apoptotic process and biological process this GO :0045295 and gamma-catenin binding and molecular function this GO :0045595 and regulation of cell differentiation and biological process this GO :0045597 and positive regulation of cell differentiation and biological process this GO :0045667 and regulation of osteoblast differentiation and biological process this GO :0045670 and regulation of osteoclast differentiation and biological process this GO :0045732 and positive regulation of protein catabolic process and biological process this GO :0045736 and negative regulation of cyclin-dependent protein serine/threonine kinase activity and biological process this GO :0045785 and positive regulation of cell adhesion and biological process this GO :0046716 and muscle cell cellular homeostasis and biological process this GO :0048538 and thymus development and biological process this GO :0050680 and negative regulation of epithelial cell proliferation and biological process this GO :0051010 and microtubule plus-end binding and molecular function this GO :0051171 and regulation of nitrogen compound metabolic process and biological process this GO :0051276 and chromosome organization and biological process this GO :0051726 and regulation of cell cycle and biological process this GO :0051781 and positive regulation of cell division and biological process this GO :0051988 and regulation of attachment of spindle microtubules to kinetochore and biological process this GO :0060041 and retina development in camera-type eye and biological process this GO :0060070 and canonical Wnt signaling pathway and biological process this GO :0060770 and negative regulation of epithelial cell proliferation involved in prostate gland development and biological process this GO :0070830 and tight junction assembly and biological process this GO :0090090 and negative regulation of canonical Wnt signaling pathway and biological process, this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0002768 and immune response-regulating cell surface receptor signaling pathway and biological process this GO :0003823 and antigen binding and molecular function this GO :0004871 and signal transducer activity and molecular function this GO :0004872 and receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006461 and protein complex assembly and biological process this GO :0006874 and cellular calcium ion homeostasis and biological process this GO :0006954 and inflammatory response and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0019899 and enzyme binding and molecular function this GO :0030168 and platelet activation and biological process this GO :0030890 and positive regulation of B cell proliferation and biological process this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0032735 and positive regulation of interleukin-12 production and biological process this GO :0032855 and positive regulation of Rac GTPase activity and biological process this GO :0035631 and CD40 receptor complex and cellular component this GO :0042100 and B cell proliferation and biological process this GO :0042113 and B cell activation and biological process this GO :0042511 and positive regulation of tyrosine phosphorylation of Stat1 protein and biological process this GO :0043089 and positive regulation of Cdc42 GTPase activity and biological process this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0043231 and intracellular membrane-bounded organelle and cellular component this GO :0043406 and positive regulation of MAP kinase activity and biological process this GO :0045087 and innate immune response and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0048304 and positive regulation of isotype switching to IgG isotypes and biological process this GO :0050776 and regulation of immune response and biological process this GO :0051023 and regulation of immunoglobulin secretion and biological process this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :0051607 and defense response to virus and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0071222 and cellular response to lipopolysaccharide and biological process this GO :0071260 and cellular response to mechanical stimulus and biological process this GO :0090037 and positive regulation of protein kinase C signaling and biological process this GO :2000353 and positive regulation of endothelial cell apoptotic process and biological process, this GO :0003823 : antigen binding, this GO :0003823 : antigen binding and also this GO :0004871 : signal transducer activity and also this GO :0004872 : receptor activity and also this GO :0005515 : protein binding and also this GO :0019899 : enzyme binding and also this GO :0031625 : ubiquitin protein ligase binding, this GO :0004871 : signal transducer activity, this GO :0004872 : receptor activity, this GO :0005488 : binding, this GO :0005488 : binding and also this GO :0005515 : protein binding and also this GO :0008013 : beta-catenin binding and also this GO :0008017 : microtubule binding and also this GO :0019887 : protein kinase regulator activity and also this GO :0019901 : protein kinase binding and also this GO :0045295 : gamma-catenin binding and also this GO :0051010 : microtubule plus-end binding, this GO :0005515 : protein binding, this GO :0005515 : protein binding, this GO :0008013 : beta-catenin binding, this GO :0008017 : microtubule binding, this GO :0019887 : protein kinase regulator activity, this GO :0019899 : enzyme binding, this GO :0019901 : protein kinase binding, this GO :0031625 : ubiquitin protein ligase binding, this GO :0045295 : gamma-catenin binding, this GO :0051010 : microtubule plus-end binding, ubiquitin protein ligase binding, 25770 and IDBG-644937 and ENSBTAG00000018852 and 533233, 42498 and IDBG-643036 and ENSBTAG00000020736 and 286849, 5 and DP3 and GS and PPP1R46, adenomatous polyposis coli |
| Identity: |
11919 |
| Gene: |
CD40 |
More about : CD40 |
| Long gene name: |
CD40 molecule |
| Synonyms gene: |
TNFRSF5 |
| Synonyms gene name: |
TNF receptor superfamily member 5 , member 5 CD40 molecule, tumor necrosis factor receptor superfamily |
| Synonyms: |
p50 Bp50 |
| Locus: |
20q13, 12 |
| Discovery year: |
1993-08-27 |
| GenBank acession: |
X60592 |
| Entrez gene record: |
958 |
| Pubmed identfication: |
7687385 2998589 |
| RefSeq identity: |
NM_001250 |
| Classification: |
CD molecules Tumor necrosis factor receptor superfamily |
| Havana BLAST/BLAT: |
OTTHUMG00000033053 |
| Locus Specific Databases: |
CD40base: Mutation registry for CD40 deficiency (previously known as TNFRSF5base) LRG_40 |