| Reacts with: |
Mouse |
| Source: |
proteins, Recombinants or rec |
| Description: |
Recombinant Mouse Thrombopoietin is produced by our expression system and the target gene encoding Ser22, Thr356 is expressed with a 6His tag at the N-terminus |
| Molecular Weight: |
36, 4 kD |
| UniProt number: |
P40226 |
| State of the product: |
Freeze-dried |
| Shipping conditions: |
Ambient temperature |
| Formulation: |
pH7, 2 um filtered solution of phosphate buffered saline, 4, Lyophilized from a 0 |
| Storage recommendations: |
-20°, Aliquots of reconstituted samples are stable at less -20°, If kept at at room temperature, If kept at at room temperature, Reconstituted protein solution should be stored at 4-7°, it is stable for 3 weeks, it is stable for 3 weeks, C, C for 2-7 days, C for 3 months, Freeze-dried proteins should be stored frozen at < |
| Reconstitution: |
Dissolve the lyophilized protein in ddH2O, Do not mix by vortex or pipetting, It is not recommended to reconstitute to a concentration less than 100 &mu, Please aliquot the reconstituted solution to minimize freeze-thaw cycles, Always centrifuge tubes before opening, g/ml |
| Purity: |
and determined by Polyacrylamide gel electrophoresis, Greater than 95% |
| Sequence of the amino acid: |
HHHHHHSPVAPACDPRLLNKLLRDSHLLHSRLSQCPDVDPLSIPVLLPAVDFSLGEWKTQTEQSKAQDILGAVSLLLEGVMAARGQLEPSCLSSLLGQLSGQVRLLLGALQGLLGTQLPLQGRTTAHKDPNALFLSLQQLLRGKVRFLLLVEGPTLCVRRTLPTTAVPSSTSQLLTLNKFPNRTSGLLETNFSVTARTAGPGLLSRLQGFRVKITPGQLNQTSRSPVQISGYLNRTHGPVNGTHGLFAGTSLQTLEASDISPGAFNKGSLAFNLQGGLPPSPSLAPDGHTPFPPSPALPTTHGSPPQLHPLFPDPSTTMPNSTAPHPVTMYPHPRNLSQET |
| Levels of endotoxin: |
11 IEU/ug, LAL test shows less than than 0 |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Group: |
recombinants |
| Gene target: |
THPO, TPO (N-6His), Thrombopoietin |
| Short name: |
THPO, TPO (N-6His), Recombinant Mouse Thrombopoietin |
| Technique: |
E, coli recombinant proteins are , mouses, novo advises they will be reconstituted in a buffer soluion or culture medium for cell culture, supplied as white sterile powder lyopillized, Recombinant, genetic recombinations , in Escherichia coli |
| Species: |
Mouses, Mouse |
| Alternative name: |
TPO (N-6His), thrombopoietin, recombinant Mouse Thrombopoietin |
| Alternative technique: |
rec |
| Alternative to gene target: |
Extracellular, MGDF and MKCSF and ML and MPLLG and THCYT1 and TPO, THPO and IDBG-635050 and ENSBTAG00000000476 and 538672, THPO and IDBG-68171 and ENSG00000090534 and 7066, Thpo and IDBG-146337 and ENSMUSG00000022847 and 21832, growth factor activity, this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0005125 and cytokine activity and molecular function this GO :0005179 and hormone activity and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0007275 and multicellular organismal development and biological process this GO :0007596 and blood coagulation and biological process this GO :0008083 and growth factor activity and molecular function this GO :0008283 and cell proliferation and biological process this GO :0030099 and myeloid cell differentiation and biological process this GO :0030168 and platelet activation and biological process this GO :0038163 and thrombopoietin-mediated signaling pathway and biological process this GO :0045654 and positive regulation of megakaryocyte differentiation and biological process this GO :0051897 and positive regulation of protein kinase B signaling and biological process this GO :0070374 and positive regulation of ERK1 and ERK2 cascade and biological process, this GO :0005125 : cytokine activity, this GO :0005125 : cytokine activity and also this GO :0005179 : hormone activity and also this GO :0008083 : growth factor activity, this GO :0005179 : hormone activity, this GO :0008083 : growth factor activity, thrombopoietin |
| Identity: |
11795 |
| Gene: |
THPO |
More about : THPO |
| Long gene name: |
thrombopoietin |
| Synonyms gene: |
MGDF |
| Synonyms: |
TPO MPLLG |
| Synonyms name: |
prepro-thrombopoietin megakaryocyte stimulating factor myeloproliferative leukemia virus oncogene ligand megakaryocyte growth and development factor MPL ligand megakaryocyte colony-stimulating factor c-mpl ligand thrombopoietin nirs variant 1 |
| Locus: |
3q27, 1 |
| Discovery year: |
1994-11-04 |
| Entrez gene record: |
7066 |
| Pubmed identfication: |
8202154 |
| RefSeq identity: |
NM_000460 |
| Classification: |
Endogenous ligands |
| Havana BLAST/BLAT: |
OTTHUMG00000156745 |