| Alternative name 1: |
Clone: 2C7, Mab anti-, UNC13D |
| Alternative name 2: |
Clone: 2C7, Mab antibody-, UNC13D |
| Alternative name 3: |
Clone: 2C7, Mab antibody-, UNC13D |
| Alternative name 4: |
anti-UNC13D Clone: 2C7 |
| Alternative name 5: |
UNC13D Clone: 2C7 |
| Clonality: |
Monoclonal Antibody |
| Description: |
Amongst the advantages of the monoclonal antibodies are: the fact that while the hybridoma takes a bit longer to be produced, If used correctly and according the protocol, in comparison to the polyclonal antibodies monoclonal antibodies are highly specific to a given epitope and can be used in applications where specific targeting is required, once the line is ready there is virtually an endless supply of these antibodie throughout time with little to no variations in recognition sites of the antigen in different batches, this antibody will provide excellent and reproducible results with guaranteed success for the tested and confirmed applications, This is a monoclonal antibody which is greatly purified and with high binding affinity for the antigen that it is risen against |
| Storage and handling: |
Antibodies in a liquid form can be shipped and stored for a short period of time at +4 degrees Celsius, antibodies that are lyophilized can be transported at ambient temperature and stored for short terms at +4 degrees Celsius, for long term storage (up to one year) 25-50% glycerol or ethylene glycol should be added and then the container has to be stored at -20°, for longer periods - at -20 , C, Generally |
| Advisory: |
For antibodies in a liquid form or reconstituted lyophilized antibodies small amounts of the soultion could be captured on the cap or the walls of the container, Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom, To keep the quality and the affinity of the antibody cycles of freezing and thawing should be avoided |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| French translation: |
anticorps |
| Gene target: |
Monoclonal 2C7, UNC13D |
| Short name: |
Mouse Monoclonal antibody- Clone: 2C7, UNC13D |
| Technique: |
Monoclonals or monoclonal antibodies, mouses, Mouse |
| Species: |
Mouses, Mouse |
| Alternative name: |
Mouse monoclonal (Antibody to)-, clonality: 2C7, elegans), unc-13 homolog D (C |
| Alternative technique: |
murine |
| Alternative to gene target: |
Plasma membranes, UNC13D and IDBG-643146 and ENSBTAG00000013556 and 506146, UNC13D and IDBG-68992 and ENSG00000092929 and 201294, Unc13d and IDBG-214399 and ENSMUSG00000057948 and 70450, elegans), protein binding, this GO :0002432 and granuloma formation and biological process this GO :0002467 and germinal center formation and biological process this GO :0005515 and protein binding and molecular function this GO :0005764 and lysosome and cellular component this GO :0005770 and late endosome and cellular component this GO :0006909 and pha this GO cytosis and biological process this GO :0016020 and membrane and cellular component this GO :0043304 and regulation of mast cell degranulation and biological process this GO :0043320 and natural killer cell degranulation and biological process this GO :0045921 and positive regulation of exocytosis and biological process this GO :0051607 and defense response to virus and biological process this GO :0055037 and recycling endosome and cellular component this GO :0070382 and exocytic vesicle and cellular component, this GO :0005515 : protein binding, this GO :0005515 : protein binding, unc-13 homolog D (C |
| Identity: |
23147 |
| Gene: |
UNC13D |
More about : UNC13D |
| Long gene name: |
unc-13 homolog D |
| Synonyms gene name: |
elegans) , unc-13 homolog D (C |
| Synonyms: |
Munc13-4 |
| Locus: |
17q25, 3 |
| Discovery year: |
2003-10-16 |
| GenBank acession: |
AK024474 |
| Entrez gene record: |
201294 |
| RefSeq identity: |
XM_113950 |
| Classification: |
UNC13 homologs |
| Havana BLAST/BLAT: |
OTTHUMG00000179895 |
| Locus Specific Databases: |
UC Hearing Loss Mutation Database LRG_122 , UNC13Dbase: Mutation registry for Familial hemophagocytic lymphohistiocytosis 3 CCHMC-BMI & |