| Alternative name 1: |
Clone: 1F2, Mab anti-, MSH6 |
| Alternative name 2: |
Clone: 1F2, Mab antibody-, MSH6 |
| Alternative name 3: |
Clone: 1F2, Mab antibody-, MSH6 |
| Alternative name 4: |
anti-MSH6 Clone: 1F2 |
| Alternative name 5: |
MSH6 Clone: 1F2 |
| Clonality: |
Monoclonal Antibody |
| Description: |
Amongst the advantages of the monoclonal antibodies are: the fact that while the hybridoma takes a bit longer to be produced, If used correctly and according the protocol, in comparison to the polyclonal antibodies monoclonal antibodies are highly specific to a given epitope and can be used in applications where specific targeting is required, once the line is ready there is virtually an endless supply of these antibodie throughout time with little to no variations in recognition sites of the antigen in different batches, this antibody will provide excellent and reproducible results with guaranteed success for the tested and confirmed applications, This is a monoclonal antibody which is greatly purified and with high binding affinity for the antigen that it is risen against |
| Storage and handling: |
Antibodies in a liquid form can be shipped and stored for a short period of time at +4 degrees Celsius, antibodies that are lyophilized can be transported at ambient temperature and stored for short terms at +4 degrees Celsius, for long term storage (up to one year) 25-50% glycerol or ethylene glycol should be added and then the container has to be stored at -20°, for longer periods - at -20 , C, Generally |
| Advisory: |
For antibodies in a liquid form or reconstituted lyophilized antibodies small amounts of the soultion could be captured on the cap or the walls of the container, Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom, To keep the quality and the affinity of the antibody cycles of freezing and thawing should be avoided |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| French translation: |
anticorps |
| Gene target: |
Monoclonal 1F2, MSH6 |
| Short name: |
Mouse Monoclonal antibody- Clone: 1F2, MSH6 |
| Technique: |
Monoclonals or monoclonal antibodies, mouses, Mouse |
| Species: |
Mouses, Mouse |
| Alternative name: |
Mouse monoclonal (Antibody to)-, clonality: 1F2, coli), mutS homolog 6 (E |
| Alternative technique: |
murine |
| Alternative to gene target: |
ADP binding, BT, GTBP and GTMBP and HNPCC5 and HSAP and p160, MSH6 and IDBG-51044 and ENSG00000116062 and 2956, Msh6 and IDBG-201548 and ENSMUSG00000005370 and 17688, coli), nuclei, this GO :0000228 and nuclear chromosome and cellular component this GO :0000287 and magnesium ion binding and molecular function this GO :0000400 and four-way junction DNA binding and molecular function this GO :0000710 and meiotic mismatch repair and biological process this GO :0000790 and nuclear chromatin and cellular component this GO :0003677 and DNA binding and molecular function this GO :0003682 and chromatin binding and molecular function this GO :0003684 and damaged DNA binding and molecular function this GO :0003690 and double-stranded DNA binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006200 and ATP catabolic process and biological process this GO :0006281 and DNA repair and biological process this GO :0006298 and mismatch repair and biological process this GO :0007131 and reciprocal meiotic recombination and biological process this GO :0008094 and DNA-dependent ATPase activity and molecular function this GO :0008340 and determination of adult lifespan and biological process this GO :0008630 and intrinsic apoptotic signaling pathway in response to DNA damage and biological process this GO :0009411 and response to UV and biological process this GO :0016446 and somatic hypermutation of immunoglobulin genes and biological process this GO :0016447 and somatic recombination of immunoglobulin gene segments and biological process this GO :0016887 and ATPase activity and molecular function this GO :0030983 and mismatched DNA binding and molecular function this GO :0032137 and guanine/thymine mispair binding and molecular function this GO :0032142 and single guanine insertion binding and molecular function this GO :0032143 and single thymine insertion binding and molecular function this GO :0032301 and MutSalpha complex and cellular component this GO :0032357 and oxidized purine DNA binding and molecular function this GO :0032405 and MutLalpha complex binding and molecular function this GO :0035064 and methylated histone binding and molecular function this GO :0043231 and intracellular membrane-bounded organelle and cellular component this GO :0043531 and ADP binding and molecular function this GO :0045190 and isotype switching and biological process this GO :0045910 and negative regulation of DNA recombination and biological process this GO :0051096 and positive regulation of helicase activity and biological process this GO :0097193 and intrinsic apoptotic signaling pathway and biological process, this GO :0000287 : magnesium ion binding, this GO :0000287 : magnesium ion binding and also this GO :0000400 : four-way junction DNA binding and also this GO :0003677 : DNA binding and also this GO :0003682 : chromatin binding and also this GO :0003684 : damaged DNA binding and also this GO :0003690 : double-stranded DNA binding and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0008094 : DNA-dependent ATPase activity and also this GO :0016887 : ATPase activity and also this GO :0030983 : mismatched DNA binding and also this GO :0032137 : guanine/thymine mispair binding and also this GO :0032142 : single guanine insertion binding and also this GO :0032143 : single thymine insertion binding and also this GO :0032357 : oxidized purine DNA binding and also this GO :0032405 : MutLalpha complex binding and also this GO :0035064 : methylated histone binding and also this GO :0043531 : ADP binding, this GO :0000400 : four-way junction DNA binding, this GO :0003677 : DNA binding, this GO :0003682 : chromatin binding, this GO :0003684 : damaged DNA binding, this GO :0003690 : double-stranded DNA binding, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0008094 : DNA-dependent ATPase activity, this GO :0016887 : ATPase activity, this GO :0030983 : mismatched DNA binding, this GO :0032137 : guanine/thymine mispair binding, this GO :0032142 : single guanine insertion binding, this GO :0032143 : single thymine insertion binding, this GO :0032357 : oxidized purine DNA binding, this GO :0032405 : MutLalpha complex binding, this GO :0035064 : methylated histone binding, this GO :0043531 : ADP binding, 98842 and IDBG-633641 and ENSBTAG00000001424 and 540526, mutS homolog 6 (E |
| Identity: |
7329 |
| Gene: |
MSH6 |
More about : MSH6 |
| Long gene name: |
mutS homolog 6 |
| Synonyms gene: |
GTBP |
| Synonyms gene name: |
coli) , coli) homolog 6 mutS homolog 6 (E, mutS (E |
| Locus: |
2p16, 3 |
| Discovery year: |
1995-08-29 |
| GenBank acession: |
U54777 |
| Entrez gene record: |
2956 |
| Pubmed identfication: |
7604266 |
| RefSeq identity: |
NM_000179 |
| Classification: |
MutS homologs PWWP domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000129129 |
| Locus Specific Databases: |
HNPCC Colon cancer gene variant databases MSH6 database at LOVD-China LRG_219 , Hereditary Non-Polyposis Colorectal Cancer |