| Alternative name 1: |
Clone: 2C6, Mab anti-, GCLM |
| Alternative name 2: |
Clone: 2C6, Mab antibody-, GCLM |
| Alternative name 3: |
Clone: 2C6, Mab antibody-, GCLM |
| Alternative name 4: |
anti-GCLM Clone: 2C6 |
| Alternative name 5: |
GCLM Clone: 2C6 |
| Clonality: |
Monoclonal Antibody |
| Description: |
Amongst the advantages of the monoclonal antibodies are: the fact that while the hybridoma takes a bit longer to be produced, If used correctly and according the protocol, in comparison to the polyclonal antibodies monoclonal antibodies are highly specific to a given epitope and can be used in applications where specific targeting is required, once the line is ready there is virtually an endless supply of these antibodie throughout time with little to no variations in recognition sites of the antigen in different batches, this antibody will provide excellent and reproducible results with guaranteed success for the tested and confirmed applications, This is a monoclonal antibody which is greatly purified and with high binding affinity for the antigen that it is risen against |
| Storage and handling: |
Antibodies in a liquid form can be shipped and stored for a short period of time at +4 degrees Celsius, antibodies that are lyophilized can be transported at ambient temperature and stored for short terms at +4 degrees Celsius, for long term storage (up to one year) 25-50% glycerol or ethylene glycol should be added and then the container has to be stored at -20°, for longer periods - at -20 , C, Generally |
| Advisory: |
For antibodies in a liquid form or reconstituted lyophilized antibodies small amounts of the soultion could be captured on the cap or the walls of the container, Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom, To keep the quality and the affinity of the antibody cycles of freezing and thawing should be avoided |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| French translation: |
anticorps |
| Gene target: |
Monoclonal 2C6, GCLM |
| Short name: |
Mouse Monoclonal antibody- Clone: 2C6, GCLM |
| Technique: |
Monoclonals or monoclonal antibodies, mouses, Mouse |
| Species: |
Mouses, Mouse |
| Alternative name: |
Mouse monoclonal (Antibody to)-, clonality: 2C6, modifier subunit, glutamate-cysteine ligase |
| Alternative technique: |
murine |
| Alternative to gene target: |
Cytoplasm, GCLM and IDBG-100355 and ENSG00000023909 and 2730, GCLM and IDBG-636430 and ENSBTAG00000007842 and 525659, GLCLR, Gclm and IDBG-191550 and ENSMUSG00000028124 and 14630, modifier subunit, protein heterodimerization activity, this GO :0000096 and sulfur amino acid metabolic process and biological process this GO :0004357 and glutamate-cysteine ligase activity and molecular function this GO :0005829 and cytosol and cellular component this GO :0006534 and cysteine metabolic process and biological process this GO :0006536 and glutamate metabolic process and biological process this GO :0006749 and glutathione metabolic process and biological process this GO :0006750 and glutathione biosynthetic process and biological process this GO :0006805 and xenobiotic metabolic process and biological process this GO :0006979 and response to oxidative stress and biological process this GO :0008637 and apoptotic mitochondrial changes and biological process this GO :0017109 and glutamate-cysteine ligase complex and cellular component this GO :0034641 and cellular nitrogen compound metabolic process and biological process this GO :0035226 and glutamate-cysteine ligase catalytic subunit binding and molecular function this GO :0035229 and positive regulation of glutamate-cysteine ligase activity and biological process this GO :0042493 and response to drug and biological process this GO :0043524 and negative regulation of neuron apoptotic process and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0046982 and protein heterodimerization activity and molecular function this GO :0050880 and regulation of blood vessel size and biological process this GO :0051409 and response to nitrosative stress and biological process this GO :0051900 and regulation of mitochondrial depolarization and biological process this GO :1901687 and glutathione derivative biosynthetic process and biological process this GO :2001237 and negative regulation of extrinsic apoptotic signaling pathway and biological process, this GO :0004357 : glutamate-cysteine ligase activity, this GO :0004357 : glutamate-cysteine ligase activity and also this GO :0035226 : glutamate-cysteine ligase catalytic subunit binding and also this GO :0046982 : protein heterodimerization activity, this GO :0035226 : glutamate-cysteine ligase catalytic subunit binding, this GO :0046982 : protein heterodimerization activity, glutamate-cysteine ligase |
| Identity: |
4312 |
| Gene: |
GCLM |
More about : GCLM |
| Long gene name: |
glutamate-cysteine ligase modifier subunit |
| Synonyms gene: |
GLCLR |
| Synonyms gene name: |
glutamate-cysteine ligase, modifier subunit |
| Synonyms name: |
gamma-glutamylcysteine synthetase |
| Locus: |
1p22, 1 |
| Discovery year: |
1995-01-30 |
| GenBank acession: |
L35546 |
| Entrez gene record: |
2730 |
| Pubmed identfication: |
7826375 |
| RefSeq identity: |
NM_002061 |
| Havana BLAST/BLAT: |
OTTHUMG00000010562 |