| Alternative name 1: |
Clone: 2A12, Mab anti-, TAB1 |
| Alternative name 2: |
Clone: 2A12, Mab antibody-, TAB1 |
| Alternative name 3: |
Clone: 2A12, Mab antibody-, TAB1 |
| Alternative name 4: |
anti-TAB1 Clone: 2A12 |
| Alternative name 5: |
TAB1 Clone: 2A12 |
| Clonality: |
Monoclonal Antibody |
| Description: |
Amongst the advantages of the monoclonal antibodies are: the fact that while the hybridoma takes a bit longer to be produced, If used correctly and according the protocol, in comparison to the polyclonal antibodies monoclonal antibodies are highly specific to a given epitope and can be used in applications where specific targeting is required, once the line is ready there is virtually an endless supply of these antibodie throughout time with little to no variations in recognition sites of the antigen in different batches, this antibody will provide excellent and reproducible results with guaranteed success for the tested and confirmed applications, This is a monoclonal antibody which is greatly purified and with high binding affinity for the antigen that it is risen against |
| Storage and handling: |
Antibodies in a liquid form can be shipped and stored for a short period of time at +4 degrees Celsius, antibodies that are lyophilized can be transported at ambient temperature and stored for short terms at +4 degrees Celsius, for long term storage (up to one year) 25-50% glycerol or ethylene glycol should be added and then the container has to be stored at -20°, for longer periods - at -20 , C, Generally |
| Advisory: |
For antibodies in a liquid form or reconstituted lyophilized antibodies small amounts of the soultion could be captured on the cap or the walls of the container, Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom, To keep the quality and the affinity of the antibody cycles of freezing and thawing should be avoided |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| French translation: |
anticorps |
| Gene target: |
Monoclonal 2A12, TAB1 |
| Short name: |
Mouse Monoclonal antibody- Clone: 2A12, TAB1 |
| Technique: |
Monoclonals or monoclonal antibodies, mouses, Mouse |
| Species: |
Mouses, Mouse |
| Alternative name: |
Mouse monoclonal (Antibody to)-, clonality: 2A12, TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| Alternative technique: |
murine |
| Alternative to gene target: |
3\'-Tab1 and MAP3K7IP1, MAP3K7IP1 and IDBG-641725 and ENSBTAG00000019828 and 519958, TAB1 and IDBG-8281 and ENSG00000100324 and 10454, Tab1 and IDBG-163423 and ENSMUSG00000022414 and 66513, leucine rich repeat containing receptor signaling pathway and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0038123 and toll-like receptor TLR1:TLR2 signaling pathway and biological process this GO :0038124 and toll-like receptor TLR6:TLR2 signaling pathway and biological process this GO :0043234 and protein complex and cellular component this GO :0043406 and positive regulation of MAP kinase activity and biological process this GO :0045087 and innate immune response and biological process this GO :0048273 and mitogen-activated protein kinase p38 binding and molecular function this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :0051403 and stress-activated MAPK cascade and biological process this GO :0070423 and nucleotide-binding oli this GO merization domain containing signaling pathway and biological process, mitogen-activated protein kinase p38 binding, nuclei, this GO :0000185 and activation of MAPKKK activity and biological process this GO :0000187 and activation of MAPK activity and biological process this GO :0001701 and in utero embryonic development and biological process this GO :0002224 and toll-like receptor signaling pathway and biological process this GO :0002755 and MyD88-dependent toll-like receptor signaling pathway and biological process this GO :0002756 and MyD88-independent toll-like receptor signaling pathway and biological process this GO :0003007 and heart morphogenesis and biological process this GO :0003824 and catalytic activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0007179 and transforming growth factor beta receptor signaling pathway and biological process this GO :0007249 and I-kappaB kinase/NF-kappaB signaling and biological process this GO :0007254 and JNK cascade and biological process this GO :0008047 and enzyme activator activity and molecular function this GO :0010008 and endosome membrane and cellular component this GO :0019209 and kinase activator activity and molecular function this GO :0030324 and lung development and biological process this GO :0032403 and protein complex binding and molecular function this GO :0034134 and toll-like receptor 2 signaling pathway and biological process this GO :0034138 and toll-like receptor 3 signaling pathway and biological process this GO :0034142 and toll-like receptor 4 signaling pathway and biological process this GO :0034146 and toll-like receptor 5 signaling pathway and biological process this GO :0034162 and toll-like receptor 9 signaling pathway and biological process this GO :0034166 and toll-like receptor 10 signaling pathway and biological process this GO :0035666 and TRIF-dependent toll-like receptor signaling pathway and biological process this GO :0035872 and nucleotide-binding domain, this GO :0003824 : catalytic activity, this GO :0003824 : catalytic activity and also this GO :0005515 : protein binding and also this GO :0008047 : enzyme activator activity and also this GO :0019209 : kinase activator activity and also this GO :0032403 : protein complex binding and also this GO :0048273 : mitogen-activated protein kinase p38 binding, this GO :0005515 : protein binding, this GO :0008047 : enzyme activator activity, this GO :0019209 : kinase activator activity, this GO :0032403 : protein complex binding, this GO :0048273 : mitogen-activated protein kinase p38 binding, TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| Identity: |
18157 |
| Gene: |
TAB1 |
More about : TAB1 |
| Long gene name: |
TGF-beta activated kinase 1 (MAP3K7) binding protein 1 |
| Synonyms gene: |
MAP3K7IP1 |
| Synonyms gene name: |
mitogen-activated protein kinase kinase kinase 7 interacting protein 1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| Synonyms name: |
TAK1-binding protein 1 mitogen-activated protein kinase kinase kinase 7 interacting protein 1 |
| Locus: |
22q13, 1 |
| Discovery year: |
2002-02-22 |
| GenBank acession: |
U49928 |
| Entrez gene record: |
10454 |
| Pubmed identfication: |
8638164 10187861 |
| RefSeq identity: |
NM_153497 |
| Havana BLAST/BLAT: |
OTTHUMG00000151102 |