| Alternative name 1: |
Clone: 1G10, Mab anti-, SMAD7 |
| Alternative name 2: |
Clone: 1G10, Mab antibody-, SMAD7 |
| Alternative name 3: |
Clone: 1G10, Mab antibody-, SMAD7 |
| Alternative name 4: |
anti-SMAD7 Clone: 1G10 |
| Alternative name 5: |
SMAD7 Clone: 1G10 |
| Clonality: |
Monoclonal Antibody |
| Description: |
Amongst the advantages of the monoclonal antibodies are: the fact that while the hybridoma takes a bit longer to be produced, If used correctly and according the protocol, in comparison to the polyclonal antibodies monoclonal antibodies are highly specific to a given epitope and can be used in applications where specific targeting is required, once the line is ready there is virtually an endless supply of these antibodie throughout time with little to no variations in recognition sites of the antigen in different batches, this antibody will provide excellent and reproducible results with guaranteed success for the tested and confirmed applications, This is a monoclonal antibody which is greatly purified and with high binding affinity for the antigen that it is risen against |
| Storage and handling: |
Antibodies in a liquid form can be shipped and stored for a short period of time at +4 degrees Celsius, antibodies that are lyophilized can be transported at ambient temperature and stored for short terms at +4 degrees Celsius, for long term storage (up to one year) 25-50% glycerol or ethylene glycol should be added and then the container has to be stored at -20°, for longer periods - at -20 , C, Generally |
| Advisory: |
For antibodies in a liquid form or reconstituted lyophilized antibodies small amounts of the soultion could be captured on the cap or the walls of the container, Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom, To keep the quality and the affinity of the antibody cycles of freezing and thawing should be avoided |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| French translation: |
anticorps |
| Gene target: |
Monoclonal 1G10, SMAD7 |
| Short name: |
Mouse Monoclonal antibody- Clone: 1G10, SMAD7 |
| Technique: |
Monoclonals or monoclonal antibodies, mouses, Mouse |
| Species: |
Mouses, Mouse |
| Alternative name: |
Mouse monoclonal (Antibody to)-, clonality: 1G10, SMAD family member 7 |
| Alternative technique: |
murine |
| Alternative to gene target: |
CRCS3 and MADH7 and MADH8, DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006367 and transcription initiation from RNA polymerase II promoter and biological process this GO :0007179 and transforming growth factor beta receptor signaling pathway and biological process this GO :0008013 and beta-catenin binding and molecular function this GO :0010467 and gene expression and biological process this GO :0010719 and negative regulation of epithelial to mesenchymal transition and biological process this GO :0010801 and negative regulation of peptidyl-threonine phosphorylation and biological process this GO :0010944 and negative regulation of transcription by competitive promoter binding and biological process this GO :0016342 and catenin complex and cellular component this GO :0017015 and regulation of transforming growth factor beta receptor signaling pathway and biological process this GO :0022409 and positive regulation of cell-cell adhesion and biological process this GO :0030336 and negative regulation of cell migration and biological process this GO :0030509 and BMP signaling pathway and biological process this GO :0030512 and negative regulation of transforming growth factor beta receptor signaling pathway and biological process this GO :0030514 and negative regulation of BMP signaling pathway and biological process this GO :0030617 and transforming growth factor beta receptor, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046872 and metal ion binding and molecular function this GO :0048185 and activin binding and molecular function this GO :0048844 and artery morphogenesis and biological process this GO :0050821 and protein stabilization and biological process this GO :0051444 and negative regulation of ubiquitin-protein transferase activity and biological process this GO :0055010 and ventricular cardiac muscle tissue morphogenesis and biological process this GO :0055117 and regulation of cardiac muscle contraction and biological process this GO :0060373 and regulation of ventricular cardiac muscle cell membrane depolarization and biological process this GO :0060389 and pathway-restricted SMAD protein phosphorylation and biological process this GO :0060394 and negative regulation of pathway-restricted SMAD protein phosphorylation and biological process this GO :0060412 and ventricular septum morphogenesis and biological process this GO :0070411 and I-SMAD binding and molecular function this GO :0071560 and cellular response to transforming growth factor beta stimulus and biological process, SMAD7 and IDBG-3195 and ENSG00000101665 and 4092, SMAD7 and IDBG-644653 and ENSBTAG00000012441 and 535916, Smad7 and IDBG-158890 and ENSMUSG00000025880 and 17131, inhibitory cytoplasmic mediator activity, inhibitory cytoplasmic mediator activity and also this GO :0031625 : ubiquitin protein ligase binding and also this GO :0034713 : type I transforming growth factor beta receptor binding and also this GO :0044212 : transcription regulatory region DNA binding and also this GO :0046872 : metal ion binding and also this GO :0048185 : activin binding and also this GO :0070411 : I-SMAD binding, inhibitory cytoplasmic mediator activity and molecular function this GO :0031397 and negative regulation of protein ubiquitination and biological process this GO :0031398 and positive regulation of protein ubiquitination and biological process this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0032436 and positive regulation of proteasomal ubiquitin-dependent protein catabolic process and biological process this GO :0032925 and regulation of activin receptor signaling pathway and biological process this GO :0033137 and negative regulation of peptidyl-serine phosphorylation and biological process this GO :0034333 and adherens junction assembly and biological process this GO :0034616 and response to laminar fluid shear stress and biological process this GO :0034629 and cellular protein complex localization and biological process this GO :0034713 and type I transforming growth factor beta receptor binding and molecular function this GO :0035556 and intracellular signal transduction and biological process this GO :0043234 and protein complex and cellular component this GO :0043433 and negative regulation of sequence-specific DNA binding transcription factor activity and biological process this GO :0044212 and transcription regulatory region DNA binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0045892 and negative regulation of transcription, nuclei, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0001657 and ureteric bud development and biological process this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005518 and collagen binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005667 and transcription factor complex and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005913 and cell-cell adherens junction and cellular component this GO :0006351 and transcription, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0005515 : protein binding and also this GO :0005518 : collagen binding and also this GO :0008013 : beta-catenin binding and also this GO :0030617 : transforming growth factor beta receptor, this GO :0005515 : protein binding, this GO :0005518 : collagen binding, this GO :0008013 : beta-catenin binding, this GO :0030617 : transforming growth factor beta receptor, this GO :0031625 : ubiquitin protein ligase binding, this GO :0034713 : type I transforming growth factor beta receptor binding, this GO :0044212 : transcription regulatory region DNA binding, this GO :0046872 : metal ion binding, this GO :0048185 : activin binding, this GO :0070411 : I-SMAD binding, transforming growth factor beta receptor, SMAD family member 7 |
| Identity: |
6773 |
| Gene: |
SMAD7 |
More about : SMAD7 |
| Long gene name: |
SMAD family member 7 |
| Synonyms gene: |
MADH8 MADH7 |
| Synonyms gene name: |
MAD, mothers against DPP homolog 7 (Drosophila) , mothers against decapentaplegic homolog 7 (Drosophila) SMAD |
| Locus: |
18q21, 1 |
| Discovery year: |
1997-08-22 |
| GenBank acession: |
AF010193 |
| Entrez gene record: |
4092 |
| Pubmed identfication: |
9256479 9730599 |
| RefSeq identity: |
NM_005904 |
| Classification: |
SMAD family |
| Havana BLAST/BLAT: |
OTTHUMG00000132655 |