| Alternative name 1: |
Clone: 2E9, Mab anti-, SMAD1 |
| Alternative name 2: |
Clone: 2E9, Mab antibody-, SMAD1 |
| Alternative name 3: |
Clone: 2E9, Mab antibody-, SMAD1 |
| Alternative name 4: |
anti-SMAD1 Clone: 2E9 |
| Alternative name 5: |
SMAD1 Clone: 2E9 |
| Clonality: |
Monoclonal Antibody |
| Description: |
Amongst the advantages of the monoclonal antibodies are: the fact that while the hybridoma takes a bit longer to be produced, If used correctly and according the protocol, in comparison to the polyclonal antibodies monoclonal antibodies are highly specific to a given epitope and can be used in applications where specific targeting is required, once the line is ready there is virtually an endless supply of these antibodie throughout time with little to no variations in recognition sites of the antigen in different batches, this antibody will provide excellent and reproducible results with guaranteed success for the tested and confirmed applications, This is a monoclonal antibody which is greatly purified and with high binding affinity for the antigen that it is risen against |
| Storage and handling: |
Antibodies in a liquid form can be shipped and stored for a short period of time at +4 degrees Celsius, antibodies that are lyophilized can be transported at ambient temperature and stored for short terms at +4 degrees Celsius, for long term storage (up to one year) 25-50% glycerol or ethylene glycol should be added and then the container has to be stored at -20°, for longer periods - at -20 , C, Generally |
| Advisory: |
For antibodies in a liquid form or reconstituted lyophilized antibodies small amounts of the soultion could be captured on the cap or the walls of the container, Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom, To keep the quality and the affinity of the antibody cycles of freezing and thawing should be avoided |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| French translation: |
anticorps |
| Gene target: |
Monoclonal 2E9, SMAD1 |
| Short name: |
Mouse Monoclonal antibody- Clone: 2E9, SMAD1 |
| Technique: |
Monoclonals or monoclonal antibodies, mouses, Mouse |
| Species: |
Mouses, Mouse |
| Alternative name: |
Mouse monoclonal (Antibody to)-, clonality: 2E9, SMAD family member 1 |
| Alternative technique: |
murine |
| Alternative to gene target: |
BSP-1 and BSP1 and JV4-1 and JV41 and MADH1 and MADR1, DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006357 and regulation of transcription from RNA polymerase II promoter and biological process this GO :0006468 and protein phosphorylation and biological process this GO :0006954 and inflammatory response and biological process this GO :0007165 and signal transduction and biological process this GO :0007179 and transforming growth factor beta receptor signaling pathway and biological process this GO :0007183 and SMAD protein complex assembly and biological process this GO :0007276 and gamete generation and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0009880 and embryonic pattern specification and biological process this GO :0010243 and response to organonitrogen compound and biological process this GO :0010628 and positive regulation of gene expression and biological process this GO :0010656 and negative regulation of muscle cell apoptotic process and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0019901 and protein kinase binding and molecular function this GO :0030509 and BMP signaling pathway and biological process this GO :0030618 and transforming growth factor beta receptor, SMAD1 and IDBG-39936 and ENSG00000170365 and 4086, SMAD1 and IDBG-629431 and ENSBTAG00000002835 and 540488, Smad1 and IDBG-170516 and ENSMUSG00000031681 and 17125, nuclei, pathway-specific cytoplasmic mediator activity, pathway-specific cytoplasmic mediator activity and also this GO :0042802 : identical protein binding and also this GO :0046872 : metal ion binding and also this GO :0070410 : co-SMAD binding and also this GO :0070411 : I-SMAD binding, pathway-specific cytoplasmic mediator activity and molecular function this GO :0030901 and midbrain development and biological process this GO :0030902 and hindbrain development and biological process this GO :0031053 and primary miRNA processing and biological process this GO :0042060 and wound healing and biological process this GO :0042493 and response to drug and biological process this GO :0042592 and homeostatic process and biological process this GO :0042802 and identical protein binding and molecular function this GO :0043234 and protein complex and cellular component this GO :0045597 and positive regulation of cell differentiation and biological process this GO :0045669 and positive regulation of osteoblast differentiation and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046872 and metal ion binding and molecular function this GO :0050775 and positive regulation of dendrite morphogenesis and biological process this GO :0051216 and cartilage development and biological process this GO :0060038 and cardiac muscle cell proliferation and biological process this GO :0060348 and bone development and biological process this GO :0061036 and positive regulation of cartilage development and biological process this GO :0070410 and co-SMAD binding and molecular function this GO :0070411 and I-SMAD binding and molecular function this GO :0071407 and cellular response to organic cyclic compound and biological process this GO :0071773 and cellular response to BMP stimulus and biological process this GO :1901522 and positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus and biological process, this GO :0000165 and MAPK cascade and biological process this GO :0000979 and RNA polymerase II core promoter sequence-specific DNA binding and molecular function this GO :0001657 and ureteric bud development and biological process this GO :0001710 and mesodermal cell fate commitment and biological process this GO :0001822 and kidney development and biological process this GO :0002051 and osteoblast fate commitment and biological process this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005057 and receptor signaling protein activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0005634 and nucleus and cellular component this GO :0005637 and nuclear inner membrane and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005667 and transcription factor complex and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005829 and cytosol and cellular component this GO :0006351 and transcription, this GO :0000979 : RNA polymerase II core promoter sequence-specific DNA binding, this GO :0000979 : RNA polymerase II core promoter sequence-specific DNA binding and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0005057 : receptor signaling protein activity and also this GO :0005515 : protein binding and also this GO :0019901 : protein kinase binding and also this GO :0030618 : transforming growth factor beta receptor, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0005057 : receptor signaling protein activity, this GO :0005515 : protein binding, this GO :0019901 : protein kinase binding, this GO :0030618 : transforming growth factor beta receptor, this GO :0042802 : identical protein binding, this GO :0046872 : metal ion binding, this GO :0070410 : co-SMAD binding, this GO :0070411 : I-SMAD binding, transforming growth factor beta receptor, SMAD family member 1 |
| Identity: |
6767 |
| Gene: |
SMAD1 |
More about : SMAD1 |
| Long gene name: |
SMAD family member 1 |
| Synonyms gene: |
MADH1 |
| Synonyms gene name: |
MAD, mothers against DPP homolog 1 (Drosophila) , mothers against decapentaplegic homolog 1 (Drosophila) SMAD |
| Synonyms: |
MADR1 JV4-1 |
| Locus: |
4q31, 21 |
| Discovery year: |
1996-11-15 |
| GenBank acession: |
U59423 |
| Entrez gene record: |
4086 |
| Pubmed identfication: |
8653785 8673135 |
| RefSeq identity: |
NM_005900 |
| Classification: |
SMAD family |
| Havana BLAST/BLAT: |
OTTHUMG00000161592 |