| Alternative name 1: |
Clone: 4B5, Mab anti-, CRKL |
| Alternative name 2: |
Clone: 4B5, Mab antibody-, CRKL |
| Alternative name 3: |
Clone: 4B5, Mab antibody-, CRKL |
| Alternative name 4: |
anti-CRKL Clone: 4B5 |
| Alternative name 5: |
CRKL Clone: 4B5 |
| Clonality: |
Monoclonal Antibody |
| Description: |
Amongst the advantages of the monoclonal antibodies are: the fact that while the hybridoma takes a bit longer to be produced, If used correctly and according the protocol, in comparison to the polyclonal antibodies monoclonal antibodies are highly specific to a given epitope and can be used in applications where specific targeting is required, once the line is ready there is virtually an endless supply of these antibodie throughout time with little to no variations in recognition sites of the antigen in different batches, this antibody will provide excellent and reproducible results with guaranteed success for the tested and confirmed applications, This is a monoclonal antibody which is greatly purified and with high binding affinity for the antigen that it is risen against |
| Storage and handling: |
Antibodies in a liquid form can be shipped and stored for a short period of time at +4 degrees Celsius, antibodies that are lyophilized can be transported at ambient temperature and stored for short terms at +4 degrees Celsius, for long term storage (up to one year) 25-50% glycerol or ethylene glycol should be added and then the container has to be stored at -20°, for longer periods - at -20 , C, Generally |
| Advisory: |
For antibodies in a liquid form or reconstituted lyophilized antibodies small amounts of the soultion could be captured on the cap or the walls of the container, Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom, To keep the quality and the affinity of the antibody cycles of freezing and thawing should be avoided |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| French translation: |
anticorps |
| Gene target: |
Monoclonal 4B5, CRKL |
| Short name: |
Mouse Monoclonal antibody- Clone: 4B5, CRKL |
| Technique: |
Monoclonals or monoclonal antibodies, mouses, Mouse |
| Species: |
Mouses, Mouse |
| Alternative name: |
Mouse monoclonal (Antibody to)-, clonality: 4B5, v-crk sarcoma virus CT10 oncogene homolog (avian)-like |
| Alternative technique: |
murine |
| Alternative to gene target: |
CRKL and IDBG-1833 and ENSG00000099942 and 1399, CRKL and IDBG-637664 and ENSBTAG00000045548 and, Crkl and IDBG-138913 and ENSMUSG00000006134 and 12929, Cytoplasm, poly(A) RNA binding, this GO :0000186 and activation of MAPKK activity and biological process this GO :0001568 and blood vessel development and biological process this GO :0004871 and signal transducer activity and molecular function this GO :0005070 and SH3/SH2 adaptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005768 and endosome and cellular component this GO :0005829 and cytosol and cellular component this GO :0007254 and JNK cascade and biological process this GO :0007265 and Ras protein signal transduction and biological process this GO :0007389 and pattern specification process and biological process this GO :0007507 and heart development and biological process this GO :0009887 and organ morphogenesis and biological process this GO :0009952 and anterior/posterior pattern specification and biological process this GO :0009967 and positive regulation of signal transduction and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0044822 and poly(A) RNA binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0048538 and thymus development and biological process this GO :0060017 and parathyroid gland development and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0004871 : signal transducer activity, this GO :0004871 : signal transducer activity and also this GO :0005070 : SH3/SH2 adaptor activity and also this GO :0005515 : protein binding and also this GO :0044822 : poly(A) RNA binding, this GO :0005070 : SH3/SH2 adaptor activity, this GO :0005515 : protein binding, this GO :0044822 : poly(A) RNA binding, v-crk sarcoma virus CT10 oncogene homolog (avian)-like |
| Identity: |
2363 |
| Gene: |
CRKL |
More about : CRKL |
| Long gene name: |
CRK like proto-oncogene, adaptor protein |
| Synonyms gene name: |
v-crk avian sarcoma virus CT10 oncogene homolog-like |
| Locus: |
22q11, 21 |
| Discovery year: |
1994-09-14 |
| Entrez gene record: |
1399 |
| Pubmed identfication: |
8361759 8798523 |
| RefSeq identity: |
NM_005207 |
| Classification: |
SH2 domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000150807 |