| Alternative name 1: |
Clone: 4B5, Mab anti-, PSMD10 |
| Alternative name 2: |
Clone: 4B5, Mab antibody-, PSMD10 |
| Alternative name 3: |
Clone: 4B5, Mab antibody-, PSMD10 |
| Alternative name 4: |
anti-PSMD10 Clone: 4B5 |
| Alternative name 5: |
PSMD10 Clone: 4B5 |
| Clonality: |
Monoclonal Antibody |
| Description: |
Amongst the advantages of the monoclonal antibodies are: the fact that while the hybridoma takes a bit longer to be produced, If used correctly and according the protocol, in comparison to the polyclonal antibodies monoclonal antibodies are highly specific to a given epitope and can be used in applications where specific targeting is required, once the line is ready there is virtually an endless supply of these antibodie throughout time with little to no variations in recognition sites of the antigen in different batches, this antibody will provide excellent and reproducible results with guaranteed success for the tested and confirmed applications, This is a monoclonal antibody which is greatly purified and with high binding affinity for the antigen that it is risen against |
| Storage and handling: |
Antibodies in a liquid form can be shipped and stored for a short period of time at +4 degrees Celsius, antibodies that are lyophilized can be transported at ambient temperature and stored for short terms at +4 degrees Celsius, for long term storage (up to one year) 25-50% glycerol or ethylene glycol should be added and then the container has to be stored at -20°, for longer periods - at -20 , C, Generally |
| Advisory: |
For antibodies in a liquid form or reconstituted lyophilized antibodies small amounts of the soultion could be captured on the cap or the walls of the container, Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom, To keep the quality and the affinity of the antibody cycles of freezing and thawing should be avoided |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| French translation: |
anticorps |
| Gene target: |
Monoclonal 4B5, PSMD10 |
| Short name: |
Mouse Monoclonal antibody- Clone: 4B5, PSMD10 |
| Technique: |
Monoclonals or monoclonal antibodies, mouses, Mouse |
| Species: |
Mouses, Mouse |
| Alternative name: |
10, Mouse monoclonal (Antibody to)-, clonality: 4B5, macropain) 26S subunit, non-ATPase, proteasome (prosome |
| Alternative technique: |
murine |
| Alternative to gene target: |
10, PSMD10 and IDBG-634094 and ENSBTAG00000013721 and 535414, PSMD10 and IDBG-81755 and ENSG00000101843 and 5716, Psmd10 and IDBG-175123 and ENSMUSG00000031429 and 53380, TAP-dependent and biological process this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005838 and proteasome regulatory particle and cellular component this GO :0006521 and regulation of cellular amino acid metabolic process and biological process this GO :0006915 and apoptotic process and biological process this GO :0006977 and DNA damage response, base subcomplex and cellular component this GO :0010467 and gene expression and biological process this GO :0016032 and viral process and biological process this GO :0016070 and RNA metabolic process and biological process this GO :0016071 and mRNA metabolic process and biological process this GO :0030307 and positive regulation of cell growth and biological process this GO :0031145 and anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process and biological process this GO :0031398 and positive regulation of protein ubiquitination and biological process this GO :0032088 and negative regulation of NF-kappaB transcription factor activity and biological process this GO :0032436 and positive regulation of proteasomal ubiquitin-dependent protein catabolic process and biological process this GO :0034641 and cellular nitrogen compound metabolic process and biological process this GO :0042590 and antigen processing and presentation of exogenous peptide antigen via MHC class I and biological process this GO :0042981 and regulation of apoptotic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043409 and negative regulation of MAPK cascade and biological process this GO :0043518 and negative regulation of DNA damage response, dJ889N15, macropain) 26S subunit, non-ATPase, nuclei, signal transduction by p53 class mediator and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0045111 and intermediate filament cytoskeleton and cellular component this GO :0045737 and positive regulation of cyclin-dependent protein serine/threonine kinase activity and biological process this GO :0051436 and negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle and biological process this GO :0051437 and positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle and biological process this GO :0051439 and regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle and biological process this GO :0070682 and proteasome regulatory particle assembly and biological process this GO :0090201 and negative regulation of release of cytochrome c from mitochondria and biological process, signal transduction by p53 class mediator resulting in cell cycle arrest and biological process this GO :0007253 and cytoplasmic sequestering of NF-kappaB and biological process this GO :0008134 and transcription factor binding and molecular function this GO :0008540 and proteasome regulatory particle, this GO :0000082 and G1/S transition of mitotic cell cycle and biological process this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0000209 and protein polyubiquitination and biological process this GO :0000278 and mitotic cell cycle and biological process this GO :0000502 and proteasome complex and cellular component this GO :0002474 and antigen processing and presentation of peptide antigen via MHC class I and biological process this GO :0002479 and antigen processing and presentation of exogenous peptide antigen via MHC class I, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0008134 : transcription factor binding, this GO :0008134 : transcription factor binding, transcription factor binding, 2 and p28 and p28(GANK), proteasome (prosome |
| Identity: |
9555 |
| Gene: |
PSMD10 |
More about : PSMD10 |
| Long gene name: |
non-ATPase 10 , proteasome 26S subunit |
| Synonyms gene name: |
10 , macropain) 26S subunit, non-ATPase, proteasome (prosome |
| Synonyms: |
p28 |
| Synonyms name: |
gankyrin |
| Locus: |
Xq22, 3 |
| Discovery year: |
1997-02-19 |
| GenBank acession: |
AB009619 |
| Entrez gene record: |
5716 |
| Pubmed identfication: |
9714768 |
| RefSeq identity: |
NM_170750 |
| Classification: |
Ankyrin repeat domain containing Proteasome |
| Havana BLAST/BLAT: |
OTTHUMG00000022177 |
| Locus Specific Databases: |
Mental Retardation database |