| Alternative name 1: |
Clone: 2E5, Mab anti-, RAPGEF3 |
| Alternative name 2: |
Clone: 2E5, Mab antibody-, RAPGEF3 |
| Alternative name 3: |
Clone: 2E5, Mab antibody-, RAPGEF3 |
| Alternative name 4: |
anti-RAPGEF3 Clone: 2E5 |
| Alternative name 5: |
RAPGEF3 Clone: 2E5 |
| Clonality: |
Monoclonal Antibody |
| Description: |
Amongst the advantages of the monoclonal antibodies are: the fact that while the hybridoma takes a bit longer to be produced, If used correctly and according the protocol, in comparison to the polyclonal antibodies monoclonal antibodies are highly specific to a given epitope and can be used in applications where specific targeting is required, once the line is ready there is virtually an endless supply of these antibodie throughout time with little to no variations in recognition sites of the antigen in different batches, this antibody will provide excellent and reproducible results with guaranteed success for the tested and confirmed applications, This is a monoclonal antibody which is greatly purified and with high binding affinity for the antigen that it is risen against |
| Storage and handling: |
Antibodies in a liquid form can be shipped and stored for a short period of time at +4 degrees Celsius, antibodies that are lyophilized can be transported at ambient temperature and stored for short terms at +4 degrees Celsius, for long term storage (up to one year) 25-50% glycerol or ethylene glycol should be added and then the container has to be stored at -20°, for longer periods - at -20 , C, Generally |
| Advisory: |
For antibodies in a liquid form or reconstituted lyophilized antibodies small amounts of the soultion could be captured on the cap or the walls of the container, Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom, To keep the quality and the affinity of the antibody cycles of freezing and thawing should be avoided |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| French translation: |
anticorps |
| Gene target: |
Monoclonal 2E5, RAPGEF3 |
| Short name: |
Mouse Monoclonal antibody- Clone: 2E5, RAPGEF3 |
| Technique: |
Monoclonals or monoclonal antibodies, mouses, Mouse |
| Species: |
Mouses, Mouse |
| Alternative name: |
Mouse monoclonal (Antibody to)-, clonality: 2E5, Rap guanine nucleotide exchange factor (GEF) 3 |
| Alternative technique: |
murine |
| Alternative to gene target: |
BT, Plasma membranes, RAPGEF3 and IDBG-28934 and ENSG00000079337 and 10411, Rapgef3 and IDBG-178771 and ENSMUSG00000022469 and 223864, bcm910 and CAMP-GEFI and EPAC and EPAC1 and HSU79275, cAMP binding, this GO :0001525 and angiogenesis and biological process this GO :0005085 and guanyl-nucleotide exchange factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005952 and cAMP-dependent protein kinase complex and cellular component this GO :0006112 and energy reserve metabolic process and biological process this GO :0007165 and signal transduction and biological process this GO :0007264 and small GTPase mediated signal transduction and biological process this GO :0007596 and blood coagulation and biological process this GO :0008283 and cell proliferation and biological process this GO :0008603 and cAMP-dependent protein kinase regulator activity and molecular function this GO :0012505 and endomembrane system and cellular component this GO :0016020 and membrane and cellular component this GO :0017034 and Rap guanyl-nucleotide exchange factor activity and molecular function this GO :0019933 and cAMP-mediated signaling and biological process this GO :0030168 and platelet activation and biological process this GO :0030552 and cAMP binding and molecular function this GO :0030822 and positive regulation of cAMP catabolic process and biological process this GO :0032486 and Rap protein signal transduction and biological process this GO :0032854 and positive regulation of Rap GTPase activity and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0043547 and positive regulation of GTPase activity and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0045766 and positive regulation of angiogenesis and biological process this GO :0045859 and regulation of protein kinase activity and biological process this GO :0050796 and regulation of insulin secretion and biological process this GO :0051056 and regulation of small GTPase mediated signal transduction and biological process this GO :0051496 and positive regulation of stress fiber assembly and biological process this GO :0061028 and establishment of endothelial barrier and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0071320 and cellular response to cAMP and biological process this GO :2000249 and regulation of actin cytoskeleton reorganization and biological process, this GO :0005085 : guanyl-nucleotide exchange factor activity, this GO :0005085 : guanyl-nucleotide exchange factor activity and also this GO :0005515 : protein binding and also this GO :0008603 : cAMP-dependent protein kinase regulator activity and also this GO :0017034 : Rap guanyl-nucleotide exchange factor activity and also this GO :0030552 : cAMP binding, this GO :0005515 : protein binding, this GO :0008603 : cAMP-dependent protein kinase regulator activity, this GO :0017034 : Rap guanyl-nucleotide exchange factor activity, this GO :0030552 : cAMP binding, 96694 and IDBG-633019 and ENSBTAG00000006828 and 535383, Rap guanine nucleotide exchange factor (GEF) 3 |
| Identity: |
16629 |
| Gene: |
RAPGEF3 |
More about : RAPGEF3 |
| Long gene name: |
Rap guanine nucleotide exchange factor 3 |
| Synonyms gene name: |
RAP guanine-nucleotide-exchange factor (GEF) 3 Rap guanine nucleotide exchange factor (GEF) 3 |
| Synonyms: |
cAMP-GEFI EPAC bcm910 |
| Synonyms name: |
exchange protein directly activated by cAMP 1 |
| Locus: |
12q13, 11 |
| Discovery year: |
2004-03-01 |
| GenBank acession: |
AK092448 |
| Entrez gene record: |
10411 |
| Pubmed identfication: |
10777494 9856955 |
| RefSeq identity: |
NM_006105 |
| Havana BLAST/BLAT: |
OTTHUMG00000133667 |