| Alternative name 1: |
Clone: 5A3, Mab anti-, LEF1 |
| Alternative name 2: |
Clone: 5A3, Mab antibody-, LEF1 |
| Alternative name 3: |
Clone: 5A3, Mab antibody-, LEF1 |
| Alternative name 4: |
anti-LEF1 Clone: 5A3 |
| Alternative name 5: |
LEF1 Clone: 5A3 |
| Clonality: |
Monoclonal Antibody |
| Description: |
Amongst the advantages of the monoclonal antibodies are: the fact that while the hybridoma takes a bit longer to be produced, If used correctly and according the protocol, in comparison to the polyclonal antibodies monoclonal antibodies are highly specific to a given epitope and can be used in applications where specific targeting is required, once the line is ready there is virtually an endless supply of these antibodie throughout time with little to no variations in recognition sites of the antigen in different batches, this antibody will provide excellent and reproducible results with guaranteed success for the tested and confirmed applications, This is a monoclonal antibody which is greatly purified and with high binding affinity for the antigen that it is risen against |
| Storage and handling: |
Antibodies in a liquid form can be shipped and stored for a short period of time at +4 degrees Celsius, antibodies that are lyophilized can be transported at ambient temperature and stored for short terms at +4 degrees Celsius, for long term storage (up to one year) 25-50% glycerol or ethylene glycol should be added and then the container has to be stored at -20°, for longer periods - at -20 , C, Generally |
| Advisory: |
For antibodies in a liquid form or reconstituted lyophilized antibodies small amounts of the soultion could be captured on the cap or the walls of the container, Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom, To keep the quality and the affinity of the antibody cycles of freezing and thawing should be avoided |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| French translation: |
anticorps |
| Gene target: |
Monoclonal 5A3, LEF1 |
| Short name: |
Mouse Monoclonal antibody- Clone: 5A3, LEF1 |
| Technique: |
Monoclonals or monoclonal antibodies, mouses, Mouse |
| Species: |
Mouses, Mouse |
| Alternative name: |
Mouse monoclonal (Antibody to)-, clonality: 5A3, lymphoid enhancer-binding factor 1 |
| Alternative technique: |
murine |
| Alternative to gene target: |
DNA binding, DNA-templated and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046632 and alpha-beta T cell differentiation and biological process this GO :0048069 and eye pigmentation and biological process this GO :0048341 and paraxial mesoderm formation and biological process this GO :0048468 and cell development and biological process this GO :0048747 and muscle fiber development and biological process this GO :0050909 and sensory perception of taste and biological process this GO :0060021 and palate development and biological process this GO :0060033 and anatomical structure regression and biological process this GO :0060070 and canonical Wnt signaling pathway and biological process this GO :0060325 and face morphogenesis and biological process this GO :0060326 and cell chemotaxis and biological process this GO :0060561 and apoptotic process involved in morphogenesis and biological process this GO :0060710 and chorio-allantoic fusion and biological process this GO :0061153 and trachea gland development and biological process this GO :0070016 and armadillo repeat domain binding and molecular function this GO :0070742 and C2H2 zinc finger domain binding and molecular function this GO :0071345 and cellular response to cytokine stimulus and biological process this GO :0071353 and cellular response to interleukin-4 and biological process this GO :0071864 and positive regulation of cell proliferation in bone marrow and biological process this GO :0071866 and negative regulation of apoptotic process in bone marrow and biological process this GO :0071895 and odontoblast differentiation and biological process this GO :0071899 and negative regulation of estrogen receptor binding and biological process this GO :0090068 and positive regulation of cell cycle process and biological process this GO :0090090 and negative regulation of canonical Wnt signaling pathway and biological process this GO :1902262 and apoptotic process involved in patterning of blood vessels and biological process, LEF1 and IDBG-33529 and ENSG00000138795 and 51176, LEF1 and IDBG-640560 and ENSBTAG00000006844 and 535399, Lef1 and IDBG-194292 and ENSMUSG00000027985 and 16842, bending, bending and also this GO :0030284 : estrogen receptor activity and also this GO :0030331 : estrogen receptor binding and also this GO :0035326 : enhancer binding and also this GO :0042393 : histone binding and also this GO :0043027 : cysteine-type endopeptidase inhibitor activity involved in apoptotic process and also this GO :0043565 : sequence-specific DNA binding and also this GO :0044212 : transcription regulatory region DNA binding and also this GO :0045295 : gamma-catenin binding and also this GO :0070016 : armadillo repeat domain binding and also this GO :0070742 : C2H2 zinc finger domain binding, bending and molecular function this GO :0010628 and positive regulation of gene expression and biological process this GO :0010718 and positive regulation of epithelial to mesenchymal transition and biological process this GO :0016055 and Wnt signaling pathway and biological process this GO :0016202 and regulation of striated muscle tissue development and biological process this GO :0021542 and dentate gyrus development and biological process this GO :0021766 and hippocampus development and biological process this GO :0021854 and hypothalamus development and biological process this GO :0021861 and forebrain radial glial cell differentiation and biological process this GO :0021873 and forebrain neuroblast division and biological process this GO :0021879 and forebrain neuron differentiation and biological process this GO :0021943 and formation of radial glial scaffolds and biological process this GO :0022407 and regulation of cell-cell adhesion and biological process this GO :0022408 and negative regulation of cell-cell adhesion and biological process this GO :0022409 and positive regulation of cell-cell adhesion and biological process this GO :0030111 and regulation of Wnt signaling pathway and biological process this GO :0030223 and neutrophil differentiation and biological process this GO :0030284 and estrogen receptor activity and molecular function this GO :0030307 and positive regulation of cell growth and biological process this GO :0030326 and embryonic limb morphogenesis and biological process this GO :0030331 and estrogen receptor binding and molecular function this GO :0030335 and positive regulation of cell migration and biological process this GO :0030509 and BMP signaling pathway and biological process this GO :0030854 and positive regulation of granulocyte differentiation and biological process this GO :0030879 and mammary gland development and biological process this GO :0032696 and negative regulation of interleukin-13 production and biological process this GO :0032713 and negative regulation of interleukin-4 production and biological process this GO :0032714 and negative regulation of interleukin-5 production and biological process this GO :0032993 and protein-DNA complex and cellular component this GO :0033153 and T cell receptor V(D)J recombination and biological process this GO :0035326 and enhancer binding and molecular function this GO :0042100 and B cell proliferation and biological process this GO :0042393 and histone binding and molecular function this GO :0042475 and odontogenesis of dentin-containing tooth and biological process this GO :0043027 and cysteine-type endopeptidase inhibitor activity involved in apoptotic process and molecular function this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043154 and negative regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0043392 and negative regulation of DNA binding and biological process this GO :0043401 and steroid hormone mediated signaling pathway and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0043586 and tongue development and biological process this GO :0043923 and positive regulation by host of viral transcription and biological process this GO :0043966 and histone H3 acetylation and biological process this GO :0043967 and histone H4 acetylation and biological process this GO :0044212 and transcription regulatory region DNA binding and molecular function this GO :0045063 and T-helper 1 cell differentiation and biological process this GO :0045295 and gamma-catenin binding and molecular function this GO :0045843 and negative regulation of striated muscle tissue development and biological process this GO :0045892 and negative regulation of transcription, nuclei, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0000977 and RNA polymerase II regulatory region sequence-specific DNA binding and molecular function this GO :0000978 and RNA polymerase II core promoter proximal region sequence-specific DNA binding and molecular function this GO :0001077 and RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and molecular function this GO :0001228 and RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and molecular function this GO :0001569 and patterning of blood vessels and biological process this GO :0001649 and osteoblast differentiation and biological process this GO :0001755 and neural crest cell migration and biological process this GO :0001756 and somitogenesis and biological process this GO :0001837 and epithelial to mesenchymal transition and biological process this GO :0001944 and vasculature development and biological process this GO :0002040 and sprouting angiogenesis and biological process this GO :0003677 and DNA binding and molecular function this GO :0003682 and chromatin binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0003705 and RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005667 and transcription factor complex and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006357 and regulation of transcription from RNA polymerase II promoter and biological process this GO :0006366 and transcription from RNA polymerase II promoter and biological process this GO :0008013 and beta-catenin binding and molecular function this GO :0008134 and transcription factor binding and molecular function this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008301 and DNA binding, this GO :0000977 : RNA polymerase II regulatory region sequence-specific DNA binding, this GO :0000977 : RNA polymerase II regulatory region sequence-specific DNA binding and also this GO :0000978 : RNA polymerase II core promoter proximal region sequence-specific DNA binding and also this GO :0001077 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and also this GO :0001228 : RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and also this GO :0003677 : DNA binding and also this GO :0003682 : chromatin binding and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0003705 : RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity and also this GO :0005515 : protein binding and also this GO :0008013 : beta-catenin binding and also this GO :0008134 : transcription factor binding and also this GO :0008301 : DNA binding, this GO :0000978 : RNA polymerase II core promoter proximal region sequence-specific DNA binding, this GO :0001077 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, this GO :0001228 : RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, this GO :0003677 : DNA binding, this GO :0003682 : chromatin binding, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0003705 : RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, this GO :0005515 : protein binding, this GO :0008013 : beta-catenin binding, this GO :0008134 : transcription factor binding, this GO :0008301 : DNA binding, this GO :0030284 : estrogen receptor activity, this GO :0030331 : estrogen receptor binding, this GO :0035326 : enhancer binding, this GO :0042393 : histone binding, this GO :0043027 : cysteine-type endopeptidase inhibitor activity involved in apoptotic process, this GO :0043565 : sequence-specific DNA binding, this GO :0044212 : transcription regulatory region DNA binding, this GO :0045295 : gamma-catenin binding, this GO :0070016 : armadillo repeat domain binding, this GO :0070742 : C2H2 zinc finger domain binding, lymphoid enhancer-binding factor 1 |
| Identity: |
6551 |
| Gene: |
LEF1 |
More about : LEF1 |
| Long gene name: |
lymphoid enhancer binding factor 1 |
| Synonyms gene name: |
lymphoid enhancer-binding factor 1 |
| Synonyms: |
TCF1ALPHA TCF10 TCF7L3 |
| Locus: |
4q25 |
| Discovery year: |
1991-06-05 |
| Entrez gene record: |
51176 |
| Pubmed identfication: |
1783375 |
| Havana BLAST/BLAT: |
OTTHUMG00000131809 |