| Alternative name 1: |
Clone: 3D5, Mab anti-, HAND2 |
| Alternative name 2: |
Clone: 3D5, Mab antibody-, HAND2 |
| Alternative name 3: |
Clone: 3D5, Mab antibody-, HAND2 |
| Alternative name 4: |
anti-HAND2 Clone: 3D5 |
| Alternative name 5: |
HAND2 Clone: 3D5 |
| Clonality: |
Monoclonal Antibody |
| Description: |
Amongst the advantages of the monoclonal antibodies are: the fact that while the hybridoma takes a bit longer to be produced, If used correctly and according the protocol, in comparison to the polyclonal antibodies monoclonal antibodies are highly specific to a given epitope and can be used in applications where specific targeting is required, once the line is ready there is virtually an endless supply of these antibodie throughout time with little to no variations in recognition sites of the antigen in different batches, this antibody will provide excellent and reproducible results with guaranteed success for the tested and confirmed applications, This is a monoclonal antibody which is greatly purified and with high binding affinity for the antigen that it is risen against |
| Storage and handling: |
Antibodies in a liquid form can be shipped and stored for a short period of time at +4 degrees Celsius, antibodies that are lyophilized can be transported at ambient temperature and stored for short terms at +4 degrees Celsius, for long term storage (up to one year) 25-50% glycerol or ethylene glycol should be added and then the container has to be stored at -20°, for longer periods - at -20 , C, Generally |
| Advisory: |
For antibodies in a liquid form or reconstituted lyophilized antibodies small amounts of the soultion could be captured on the cap or the walls of the container, Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom, To keep the quality and the affinity of the antibody cycles of freezing and thawing should be avoided |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| French translation: |
anticorps |
| Gene target: |
Monoclonal 3D5, HAND2 |
| Short name: |
Mouse Monoclonal antibody- Clone: 3D5, HAND2 |
| Technique: |
Monoclonals or monoclonal antibodies, mouses, Mouse |
| Species: |
Mouses, Mouse |
| Alternative name: |
Mouse monoclonal (Antibody to)-, clonality: 3D5, heart and neural crest derivatives expressed 2 |
| Alternative technique: |
murine |
| Alternative to gene target: |
DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006915 and apoptotic process and biological process this GO :0007507 and heart development and biological process this GO :0007512 and adult heart development and biological process this GO :0008134 and transcription factor binding and molecular function this GO :0010463 and mesenchymal cell proliferation and biological process this GO :0010667 and negative regulation of cardiac muscle cell apoptotic process and biological process this GO :0014032 and neural crest cell development and biological process this GO :0033613 and activating transcription factor binding and molecular function this GO :0042475 and odontogenesis of dentin-containing tooth and biological process this GO :0042733 and embryonic digit morphogenesis and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043234 and protein complex and cellular component this GO :0043392 and negative regulation of DNA binding and biological process this GO :0043433 and negative regulation of sequence-specific DNA binding transcription factor activity and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0043586 and tongue development and biological process this GO :0044212 and transcription regulatory region DNA binding and molecular function this GO :0045668 and negative regulation of osteoblast differentiation and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046982 and protein heterodimerization activity and molecular function this GO :0046983 and protein dimerization activity and molecular function this GO :0048485 and sympathetic nervous system development and biological process this GO :0048538 and thymus development and biological process this GO :0048935 and peripheral nervous system neuron development and biological process this GO :0060021 and palate development and biological process this GO :0060485 and mesenchyme development and biological process this GO :0060536 and cartilage morphogenesis and biological process this GO :0060982 and coronary artery morphogenesis and biological process this GO :0061032 and visceral serous pericardium development and biological process this GO :0061309 and cardiac neural crest cell development involved in outflow tract morphogenesis and biological process this GO :0061325 and cell proliferation involved in outflow tract morphogenesis and biological process this GO :0061371 and determination of heart left/right asymmetry and biological process this GO :0070888 and E-box binding and molecular function this GO :2000679 and positive regulation of transcription regulatory region DNA binding and biological process this GO :2000763 and positive regulation of transcription from RNA polymerase II promoter involved in norepinephrine biosynthetic process and biological process this GO :2000764 and positive regulation of semaphorin-plexin signaling pathway involved in outflow tract morphogenesis and biological process, E-box binding, HAND2 and IDBG-44790 and ENSG00000164107 and 9464, HAND2 and IDBG-629312 and ENSBTAG00000044123 and 781874, Hand2 and IDBG-156149 and ENSMUSG00000038193 and 15111, bHLHa26 and dHand and DHAND2 and Hed and Thing2, nuclei, this GO :0000790 and nuclear chromatin and cellular component this GO :0000977 and RNA polymerase II regulatory region sequence-specific DNA binding and molecular function this GO :0001077 and RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and molecular function this GO :0001525 and angiogenesis and biological process this GO :0001701 and in utero embryonic development and biological process this GO :0001947 and heart looping and biological process this GO :0001967 and suckling behavior and biological process this GO :0003007 and heart morphogenesis and biological process this GO :0003219 and cardiac right ventricle formation and biological process this GO :0003253 and cardiac neural crest cell migration involved in outflow tract morphogenesis and biological process this GO :0003266 and regulation of secondary heart field cardioblast proliferation and biological process this GO :0003278 and apoptotic process involved in heart morphogenesis and biological process this GO :0003357 and noradrenergic neuron differentiation and biological process this GO :0003680 and AT DNA binding and molecular function this GO :0003713 and transcription coactivator activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005667 and transcription factor complex and cellular component this GO :0006351 and transcription, this GO :0000977 : RNA polymerase II regulatory region sequence-specific DNA binding, this GO :0000977 : RNA polymerase II regulatory region sequence-specific DNA binding and also this GO :0001077 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and also this GO :0003680 : AT DNA binding and also this GO :0003713 : transcription coactivator activity and also this GO :0005515 : protein binding and also this GO :0008134 : transcription factor binding and also this GO :0033613 : activating transcription factor binding and also this GO :0042803 : protein homodimerization activity and also this GO :0043565 : sequence-specific DNA binding and also this GO :0044212 : transcription regulatory region DNA binding and also this GO :0046982 : protein heterodimerization activity and also this GO :0046983 : protein dimerization activity and also this GO :0070888 : E-box binding, this GO :0001077 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, this GO :0003680 : AT DNA binding, this GO :0003713 : transcription coactivator activity, this GO :0005515 : protein binding, this GO :0008134 : transcription factor binding, this GO :0033613 : activating transcription factor binding, this GO :0042803 : protein homodimerization activity, this GO :0043565 : sequence-specific DNA binding, this GO :0044212 : transcription regulatory region DNA binding, this GO :0046982 : protein heterodimerization activity, this GO :0046983 : protein dimerization activity, this GO :0070888 : E-box binding, heart and neural crest derivatives expressed 2 |
| Identity: |
4808 |
| Gene: |
HAND2 |
More about : HAND2 |
| Long gene name: |
heart and neural crest derivatives expressed 2 |
| Synonyms: |
dHand Thing2 Hed bHLHa26 |
| Locus: |
4q34, 1 |
| Discovery year: |
1999-05-17 |
| GenBank acession: |
AF087941 |
| Entrez gene record: |
9464 |
| Pubmed identfication: |
9878849 |
| Classification: |
Basic helix-loop-helix proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000160775 |