| Alternative name 1: |
Clone: 3E11, Mab anti-, TWIST1 |
| Alternative name 2: |
Clone: 3E11, Mab antibody-, TWIST1 |
| Alternative name 3: |
Clone: 3E11, Mab antibody-, TWIST1 |
| Alternative name 4: |
anti-TWIST1 Clone: 3E11 |
| Alternative name 5: |
TWIST1 Clone: 3E11 |
| Clonality: |
Monoclonal Antibody |
| Description: |
Amongst the advantages of the monoclonal antibodies are: the fact that while the hybridoma takes a bit longer to be produced, If used correctly and according the protocol, in comparison to the polyclonal antibodies monoclonal antibodies are highly specific to a given epitope and can be used in applications where specific targeting is required, once the line is ready there is virtually an endless supply of these antibodie throughout time with little to no variations in recognition sites of the antigen in different batches, this antibody will provide excellent and reproducible results with guaranteed success for the tested and confirmed applications, This is a monoclonal antibody which is greatly purified and with high binding affinity for the antigen that it is risen against |
| Storage and handling: |
Antibodies in a liquid form can be shipped and stored for a short period of time at +4 degrees Celsius, antibodies that are lyophilized can be transported at ambient temperature and stored for short terms at +4 degrees Celsius, for long term storage (up to one year) 25-50% glycerol or ethylene glycol should be added and then the container has to be stored at -20°, for longer periods - at -20 , C, Generally |
| Advisory: |
For antibodies in a liquid form or reconstituted lyophilized antibodies small amounts of the soultion could be captured on the cap or the walls of the container, Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom, To keep the quality and the affinity of the antibody cycles of freezing and thawing should be avoided |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| French translation: |
anticorps |
| Gene target: |
Monoclonal 3E11, TWIST1 |
| Short name: |
Mouse Monoclonal antibody- Clone: 3E11, TWIST1 |
| Technique: |
Monoclonals or monoclonal antibodies, mouses, Mouse |
| Species: |
Mouses, Mouse |
| Alternative name: |
Mouse monoclonal (Antibody to)-, clonality: 3E11, twist homolog 1 (Drosophila) |
| Alternative technique: |
murine |
| Alternative to gene target: |
ACS3 and bHLHa38 and BPES2 and BPES3 and CRS and CRS1 and SCS and TWIST, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046982 and protein heterodimerization activity and molecular function this GO :0046983 and protein dimerization activity and molecular function this GO :0048511 and rhythmic process and biological process this GO :0048642 and negative regulation of skeletal muscle tissue development and biological process this GO :0048701 and embryonic cranial skeleton morphogenesis and biological process this GO :0048704 and embryonic skeletal system morphogenesis and biological process this GO :0050679 and positive regulation of epithelial cell proliferation and biological process this GO :0060021 and palate development and biological process this GO :0060348 and bone development and biological process this GO :0060363 and cranial suture morphogenesis and biological process this GO :0060900 and embryonic camera-type eye formation and biological process this GO :0061029 and eyelid development in camera-type eye and biological process this GO :0061309 and cardiac neural crest cell development involved in outflow tract morphogenesis and biological process this GO :0070888 and E-box binding and molecular function this GO :0071363 and cellular response to growth factor stimulus and biological process this GO :0071456 and cellular response to hypoxia and biological process this GO :0071639 and positive regulation of monocyte chemotactic protein-1 production and biological process this GO :2000147 and positive regulation of cell motility and biological process this GO :2000276 and negative regulation of oxidative phosphorylation uncoupler activity and biological process this GO :2000679 and positive regulation of transcription regulatory region DNA binding and biological process this GO :2000773 and negative regulation of cellular senescence and biological process this GO :2000778 and positive regulation of interleukin-6 secretion and biological process this GO :2000780 and negative regulation of double-strand break repair and biological process this GO :2000793 and cell proliferation involved in heart valve development and biological process this GO :2000802 and positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation and biological process, E-box binding, TWIST1 and IDBG-646996 and ENSBTAG00000046922 and 782170, TWIST1 and IDBG-9102 and ENSG00000122691 and 7291, Twist1 and IDBG-134527 and ENSMUSG00000035799 and 22160, nuclei, signal transduction by p53 class mediator and biological process this GO :0044092 and negative regulation of molecular function and biological process this GO :0045596 and negative regulation of cell differentiation and biological process this GO :0045668 and negative regulation of osteoblast differentiation and biological process this GO :0045766 and positive regulation of angiogenesis and biological process this GO :0045843 and negative regulation of striated muscle tissue development and biological process this GO :0045892 and negative regulation of transcription, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0000981 and sequence-specific DNA binding RNA polymerase II transcription factor activity and molecular function this GO :0001503 and ossification and biological process this GO :0001649 and osteoblast differentiation and biological process this GO :0001701 and in utero embryonic development and biological process this GO :0001764 and neuron migration and biological process this GO :0001843 and neural tube closure and biological process this GO :0003180 and aortic valve morphogenesis and biological process this GO :0003183 and mitral valve morphogenesis and biological process this GO :0003203 and endocardial cushion morphogenesis and biological process this GO :0003253 and cardiac neural crest cell migration involved in outflow tract morphogenesis and biological process this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0006366 and transcription from RNA polymerase II promoter and biological process this GO :0007517 and muscle organ development and biological process this GO :0008134 and transcription factor binding and molecular function this GO :0010628 and positive regulation of gene expression and biological process this GO :0010718 and positive regulation of epithelial to mesenchymal transition and biological process this GO :0014067 and negative regulation of phosphatidylinositol 3-kinase signaling and biological process this GO :0019904 and protein domain specific binding and molecular function this GO :0030154 and cell differentiation and biological process this GO :0030326 and embryonic limb morphogenesis and biological process this GO :0030500 and regulation of bone mineralization and biological process this GO :0032000 and positive regulation of fatty acid beta-oxidation and biological process this GO :0032720 and negative regulation of tumor necrosis factor production and biological process this GO :0032760 and positive regulation of tumor necrosis factor production and biological process this GO :0033128 and negative regulation of histone phosphorylation and biological process this GO :0035067 and negative regulation of histone acetylation and biological process this GO :0035115 and embryonic forelimb morphogenesis and biological process this GO :0035116 and embryonic hindlimb morphogenesis and biological process this GO :0035137 and hindlimb morphogenesis and biological process this GO :0035359 and negative regulation of peroxisome proliferator activated receptor signaling pathway and biological process this GO :0042473 and outer ear morphogenesis and biological process this GO :0042476 and odontogenesis and biological process this GO :0042733 and embryonic digit morphogenesis and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043425 and bHLH transcription factor binding and molecular function this GO :0043433 and negative regulation of sequence-specific DNA binding transcription factor activity and biological process this GO :0043518 and negative regulation of DNA damage response, this GO :0000981 : sequence-specific DNA binding RNA polymerase II transcription factor activity, this GO :0000981 : sequence-specific DNA binding RNA polymerase II transcription factor activity and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0005515 : protein binding and also this GO :0008134 : transcription factor binding and also this GO :0019904 : protein domain specific binding and also this GO :0042803 : protein homodimerization activity and also this GO :0043425 : bHLH transcription factor binding and also this GO :0046982 : protein heterodimerization activity and also this GO :0046983 : protein dimerization activity and also this GO :0070888 : E-box binding, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0005515 : protein binding, this GO :0008134 : transcription factor binding, this GO :0019904 : protein domain specific binding, this GO :0042803 : protein homodimerization activity, this GO :0043425 : bHLH transcription factor binding, this GO :0046982 : protein heterodimerization activity, this GO :0046983 : protein dimerization activity, this GO :0070888 : E-box binding, twist homolog 1 (Drosophila) |
| Identity: |
12428 |
| Gene: |
TWIST1 |
More about : TWIST1 |
| Long gene name: |
twist family bHLH transcription factor 1 |
| Synonyms gene: |
ACS3 BPES3 TWIST CRS |
| Synonyms gene name: |
blepharophimosis, epicanthus inversus and ptosis 3 acrocephalosyndactyly 3 twist homolog 1 (Drosophila) twist basic helix-loop-helix transcription factor 1 craniosynostosis |
| Synonyms: |
SCS H-twist BPES2 bHLHa38 CRS1 |
| Synonyms name: |
Saethre-Chotzen syndrome |
| Locus: |
7p21, 1 |
| Discovery year: |
1997-07-01 |
| GenBank acession: |
U80998 |
| Entrez gene record: |
7291 |
| Pubmed identfication: |
8995765 11474656 17343269 |
| RefSeq identity: |
NM_000474 |
| Classification: |
Basic helix-loop-helix proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000090821 |