| Alternative name 1: |
Clone: 7A10, Mab anti-, TFAP4 |
| Alternative name 2: |
Clone: 7A10, Mab antibody-, TFAP4 |
| Alternative name 3: |
Clone: 7A10, Mab antibody-, TFAP4 |
| Alternative name 4: |
anti-TFAP4 Clone: 7A10 |
| Alternative name 5: |
TFAP4 Clone: 7A10 |
| Clonality: |
Monoclonal Antibody |
| Description: |
Amongst the advantages of the monoclonal antibodies are: the fact that while the hybridoma takes a bit longer to be produced, If used correctly and according the protocol, in comparison to the polyclonal antibodies monoclonal antibodies are highly specific to a given epitope and can be used in applications where specific targeting is required, once the line is ready there is virtually an endless supply of these antibodie throughout time with little to no variations in recognition sites of the antigen in different batches, this antibody will provide excellent and reproducible results with guaranteed success for the tested and confirmed applications, This is a monoclonal antibody which is greatly purified and with high binding affinity for the antigen that it is risen against |
| Storage and handling: |
Antibodies in a liquid form can be shipped and stored for a short period of time at +4 degrees Celsius, antibodies that are lyophilized can be transported at ambient temperature and stored for short terms at +4 degrees Celsius, for long term storage (up to one year) 25-50% glycerol or ethylene glycol should be added and then the container has to be stored at -20°, for longer periods - at -20 , C, Generally |
| Advisory: |
For antibodies in a liquid form or reconstituted lyophilized antibodies small amounts of the soultion could be captured on the cap or the walls of the container, Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom, To keep the quality and the affinity of the antibody cycles of freezing and thawing should be avoided |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| French translation: |
anticorps |
| Gene target: |
Monoclonal 7A10, TFAP4 |
| Short name: |
Mouse Monoclonal antibody- Clone: 7A10, TFAP4 |
| Technique: |
Monoclonals or monoclonal antibodies, mouses, Mouse |
| Species: |
Mouses, Mouse |
| Alternative name: |
Mouse monoclonal (Antibody to)-, clonality: 7A10, transcription factor AP-4 (activating enhancer binding protein 4) |
| Alternative technique: |
murine |
| Alternative to gene target: |
AP-4 and bHLHc41, DNA-templated and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046983 and protein dimerization activity and molecular function this GO :0070888 and E-box binding and molecular function this GO :0071157 and negative regulation of cell cycle arrest and biological process this GO :0071549 and cellular response to dexamethasone stimulus and biological process this GO :2001269 and positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway and biological process, E-box binding, TFAP4 and IDBG-12589 and ENSG00000090447 and 7023, TFAP4 and IDBG-636211 and ENSBTAG00000033174 and 540757, Tfap4 and IDBG-129693 and ENSMUSG00000005718 and 83383, nuclei, signal transduction by p53 class mediator resulting in transcription of p21 class mediator and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0010629 and negative regulation of gene expression and biological process this GO :0017053 and transcriptional repressor complex and cellular component this GO :0042803 and protein homodimerization activity and molecular function this GO :0042826 and histone deacetylase binding and molecular function this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043392 and negative regulation of DNA binding and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0043922 and negative regulation by host of viral transcription and biological process this GO :0043923 and positive regulation by host of viral transcription and biological process this GO :0044212 and transcription regulatory region DNA binding and molecular function this GO :0045736 and negative regulation of cyclin-dependent protein serine/threonine kinase activity and biological process this GO :0045892 and negative regulation of transcription, this GO :0000978 and RNA polymerase II core promoter proximal region sequence-specific DNA binding and molecular function this GO :0001077 and RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and molecular function this GO :0003677 and DNA binding and molecular function this GO :0003705 and RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0006366 and transcription from RNA polymerase II promoter and biological process this GO :0006461 and protein complex assembly and biological process this GO :0006978 and DNA damage response, this GO :0000978 : RNA polymerase II core promoter proximal region sequence-specific DNA binding, this GO :0000978 : RNA polymerase II core promoter proximal region sequence-specific DNA binding and also this GO :0001077 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and also this GO :0003677 : DNA binding and also this GO :0003705 : RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity and also this GO :0005515 : protein binding and also this GO :0042803 : protein homodimerization activity and also this GO :0042826 : histone deacetylase binding and also this GO :0043565 : sequence-specific DNA binding and also this GO :0044212 : transcription regulatory region DNA binding and also this GO :0046983 : protein dimerization activity and also this GO :0070888 : E-box binding, this GO :0001077 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, this GO :0003677 : DNA binding, this GO :0003705 : RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, this GO :0005515 : protein binding, this GO :0042803 : protein homodimerization activity, this GO :0042826 : histone deacetylase binding, this GO :0043565 : sequence-specific DNA binding, this GO :0044212 : transcription regulatory region DNA binding, this GO :0046983 : protein dimerization activity, this GO :0070888 : E-box binding, transcription factor AP-4 (activating enhancer binding protein 4) |
| Identity: |
11745 |
| Gene: |
TFAP4 |
More about : TFAP4 |
| Long gene name: |
transcription factor AP-4 |
| Synonyms gene name: |
transcription factor AP-4 (activating enhancer-binding protein 4) |
| Synonyms: |
AP-4 bHLHc41 |
| Locus: |
16p13, 3 |
| Discovery year: |
1995-03-01 |
| GenBank acession: |
X57435 |
| Entrez gene record: |
7023 |
| Pubmed identfication: |
2123466 |
| RefSeq identity: |
NM_003223 |
| Classification: |
Basic helix-loop-helix proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000129435 |