| Alternative name 1: |
Clone: 1B12, Mab anti-, STAT5A |
| Alternative name 2: |
Clone: 1B12, Mab antibody-, STAT5A |
| Alternative name 3: |
Clone: 1B12, Mab antibody-, STAT5A |
| Alternative name 4: |
anti-STAT5A Clone: 1B12 |
| Alternative name 5: |
STAT5A Clone: 1B12 |
| Clonality: |
Monoclonal Antibody |
| Description: |
Amongst the advantages of the monoclonal antibodies are: the fact that while the hybridoma takes a bit longer to be produced, If used correctly and according the protocol, in comparison to the polyclonal antibodies monoclonal antibodies are highly specific to a given epitope and can be used in applications where specific targeting is required, once the line is ready there is virtually an endless supply of these antibodie throughout time with little to no variations in recognition sites of the antigen in different batches, this antibody will provide excellent and reproducible results with guaranteed success for the tested and confirmed applications, This is a monoclonal antibody which is greatly purified and with high binding affinity for the antigen that it is risen against |
| Storage and handling: |
Antibodies in a liquid form can be shipped and stored for a short period of time at +4 degrees Celsius, antibodies that are lyophilized can be transported at ambient temperature and stored for short terms at +4 degrees Celsius, for long term storage (up to one year) 25-50% glycerol or ethylene glycol should be added and then the container has to be stored at -20°, for longer periods - at -20 , C, Generally |
| Advisory: |
For antibodies in a liquid form or reconstituted lyophilized antibodies small amounts of the soultion could be captured on the cap or the walls of the container, Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom, To keep the quality and the affinity of the antibody cycles of freezing and thawing should be avoided |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| French translation: |
anticorps |
| Gene target: |
Monoclonal 1B12, STAT5A |
| Short name: |
Mouse Monoclonal antibody- Clone: 1B12, STAT5A |
| Technique: |
Monoclonals or monoclonal antibodies, mouses, Mouse |
| Species: |
Mouses, Mouse |
| Alternative name: |
Mouse monoclonal (Antibody to)-, clonality: 1B12, signal transducer and activator on transcription 5A |
| Alternative technique: |
murine |
| Alternative to gene target: |
DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006357 and regulation of transcription from RNA polymerase II promoter and biological process this GO :0006549 and isoleucine metabolic process and biological process this GO :0006573 and valine metabolic process and biological process this GO :0006600 and creatine metabolic process and biological process this GO :0006631 and fatty acid metabolic process and biological process this GO :0007165 and signal transduction and biological process this GO :0007259 and JAK-STAT cascade and biological process this GO :0007565 and female pregnancy and biological process this GO :0007595 and lactation and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0018108 and peptidyl-tyrosine phosphorylation and biological process this GO :0019218 and regulation of steroid metabolic process and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0019530 and taurine metabolic process and biological process this GO :0019903 and protein phosphatase binding and molecular function this GO :0019915 and lipid storage and biological process this GO :0030155 and regulation of cell adhesion and biological process this GO :0030856 and regulation of epithelial cell differentiation and biological process this GO :0030879 and mammary gland development and biological process this GO :0032825 and positive regulation of natural killer cell differentiation and biological process this GO :0033026 and negative regulation of mast cell apoptotic process and biological process this GO :0033077 and T cell differentiation in thymus and biological process this GO :0038161 and prolactin signaling pathway and biological process this GO :0040014 and regulation of multicellular organism growth and biological process this GO :0040018 and positive regulation of multicellular organism growth and biological process this GO :0042104 and positive regulation of activated T cell proliferation and biological process this GO :0043029 and T cell homeostasis and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043434 and response to peptide hormone and biological process this GO :0045086 and positive regulation of interleukin-2 biosynthetic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045579 and positive regulation of B cell differentiation and biological process this GO :0045588 and positive regulation of gamma-delta T cell differentiation and biological process this GO :0045621 and positive regulation of lymphocyte differentiation and biological process this GO :0045647 and negative regulation of erythrocyte differentiation and biological process this GO :0045931 and positive regulation of mitotic cell cycle and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0045954 and positive regulation of natural killer cell mediated cytotoxicity and biological process this GO :0046449 and creatinine metabolic process and biological process this GO :0046543 and development of secondary female sexual characteristics and biological process this GO :0046544 and development of secondary male sexual characteristics and biological process this GO :0048541 and Peyer's patch development and biological process this GO :0050729 and positive regulation of inflammatory response and biological process this GO :0060376 and positive regulation of mast cell differentiation and biological process this GO :0060397 and JAK-STAT cascade involved in growth hormone signaling pathway and biological process this GO :0060740 and prostate gland epithelium morphogenesis and biological process this GO :0060742 and epithelial cell differentiation involved in prostate gland development and biological process this GO :0061180 and mammary gland epithelium development and biological process this GO :0070668 and positive regulation of mast cell proliferation and biological process this GO :0097011 and cellular response to granulocyte macrophage colony-stimulating factor stimulus and biological process, MGF and STAT5, STAT5A and IDBG-50625 and ENSG00000126561 and 6776, STAT5A and IDBG-640187 and ENSBTAG00000009496 and 282375, Stat5a and IDBG-211618 and ENSMUSG00000004043 and 20850, nuclei, protein phosphatase binding, this GO :0000255 and allantoin metabolic process and biological process this GO :0000979 and RNA polymerase II core promoter sequence-specific DNA binding and molecular function this GO :0001553 and luteinization and biological process this GO :0001779 and natural killer cell differentiation and biological process this GO :0003677 and DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0004871 and signal transducer activity and molecular function this GO :0005509 and calcium ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006101 and citrate metabolic process and biological process this GO :0006103 and 2-oxoglutarate metabolic process and biological process this GO :0006105 and succinate metabolic process and biological process this GO :0006107 and oxaloacetate metabolic process and biological process this GO :0006351 and transcription, this GO :0000979 : RNA polymerase II core promoter sequence-specific DNA binding, this GO :0000979 : RNA polymerase II core promoter sequence-specific DNA binding and also this GO :0003677 : DNA binding and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0004871 : signal transducer activity and also this GO :0005509 : calcium ion binding and also this GO :0005515 : protein binding and also this GO :0019903 : protein phosphatase binding, this GO :0003677 : DNA binding, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0004871 : signal transducer activity, this GO :0005509 : calcium ion binding, this GO :0005515 : protein binding, this GO :0019903 : protein phosphatase binding, signal transducer and activator of transcription 5A |
| Identity: |
11366 |
| Gene: |
STAT5A |
More about : STAT5A |
| Long gene name: |
signal transducer and activator of transcription 5A |
| Synonyms gene: |
STAT5 |
| Synonyms: |
MGF |
| Locus: |
17q21, 2 |
| Discovery year: |
1995-11-09 |
| GenBank acession: |
U43185 |
| Entrez gene record: |
6776 |
| Pubmed identfication: |
7719937 8631883 |
| RefSeq identity: |
NM_003152 |
| Classification: |
SH2 domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000150725 |