| Alternative name 1: |
Clone: 2G1, Mab anti-, SPI1 |
| Alternative name 2: |
Clone: 2G1, Mab antibody-, SPI1 |
| Alternative name 3: |
Clone: 2G1, Mab antibody-, SPI1 |
| Alternative name 4: |
anti-SPI1 Clone: 2G1 |
| Alternative name 5: |
SPI1 Clone: 2G1 |
| Clonality: |
Monoclonal Antibody |
| Description: |
Amongst the advantages of the monoclonal antibodies are: the fact that while the hybridoma takes a bit longer to be produced, If used correctly and according the protocol, in comparison to the polyclonal antibodies monoclonal antibodies are highly specific to a given epitope and can be used in applications where specific targeting is required, once the line is ready there is virtually an endless supply of these antibodie throughout time with little to no variations in recognition sites of the antigen in different batches, this antibody will provide excellent and reproducible results with guaranteed success for the tested and confirmed applications, This is a monoclonal antibody which is greatly purified and with high binding affinity for the antigen that it is risen against |
| Storage and handling: |
Antibodies in a liquid form can be shipped and stored for a short period of time at +4 degrees Celsius, antibodies that are lyophilized can be transported at ambient temperature and stored for short terms at +4 degrees Celsius, for long term storage (up to one year) 25-50% glycerol or ethylene glycol should be added and then the container has to be stored at -20°, for longer periods - at -20 , C, Generally |
| Advisory: |
For antibodies in a liquid form or reconstituted lyophilized antibodies small amounts of the soultion could be captured on the cap or the walls of the container, Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom, To keep the quality and the affinity of the antibody cycles of freezing and thawing should be avoided |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| French translation: |
anticorps |
| Gene target: |
Monoclonal 2G1, SPI1 |
| Short name: |
Mouse Monoclonal antibody- Clone: 2G1, SPI1 |
| Technique: |
Monoclonals or monoclonal antibodies, mouses, Mouse |
| Species: |
Mouses, Mouse |
| Alternative name: |
Mouse monoclonal (Antibody to)-, clonality: 2G1, spleen focus forming virus (SFFV) proviral integration oncogene spi1 |
| Alternative technique: |
murine |
| Alternative to gene target: |
BT, DNA-templated and biological process this GO :0006357 and regulation of transcription from RNA polymerase II promoter and biological process this GO :0006366 and transcription from RNA polymerase II promoter and biological process this GO :0030098 and lymphocyte differentiation and biological process this GO :0030218 and erythrocyte differentiation and biological process this GO :0030225 and macrophage differentiation and biological process this GO :0030851 and granulocyte differentiation and biological process this GO :0035019 and somatic stem cell maintenance and biological process this GO :0043011 and myeloid dendritic cell differentiation and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0043966 and histone H3 acetylation and biological process this GO :0044027 and hypermethylation of CpG island and biological process this GO :0045087 and innate immune response and biological process this GO :0045347 and negative regulation of MHC class II biosynthetic process and biological process this GO :0045646 and regulation of erythrocyte differentiation and biological process this GO :0045814 and negative regulation of gene expression, DNA-templated and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0051525 and NFAT protein binding and molecular function this GO :0060033 and anatomical structure regression and biological process this GO :0090241 and negative regulation of histone H4 acetylation and biological process this GO :1902262 and apoptotic process involved in patterning of blood vessels and biological process, NFAT protein binding, OF and PU, SPI1 and IDBG-43260 and ENSG00000066336 and 6688, Sfpi1 and IDBG-190185 and ENSMUSG00000002111 and 20375, epigenetic and biological process this GO :0045892 and negative regulation of transcription, nuclei, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0000790 and nuclear chromatin and cellular component this GO :0000978 and RNA polymerase II core promoter proximal region sequence-specific DNA binding and molecular function this GO :0000979 and RNA polymerase II core promoter sequence-specific DNA binding and molecular function this GO :0000980 and RNA polymerase II distal enhancer sequence-specific DNA binding and molecular function this GO :0000981 and sequence-specific DNA binding RNA polymerase II transcription factor activity and molecular function this GO :0001047 and core promoter binding and molecular function this GO :0001077 and RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and molecular function this GO :0001078 and RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription and molecular function this GO :0001085 and RNA polymerase II transcription factor binding and molecular function this GO :0001205 and RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and molecular function this GO :0001944 and vasculature development and biological process this GO :0002320 and lymphoid progenitor cell differentiation and biological process this GO :0002573 and myeloid leukocyte differentiation and biological process this GO :0003677 and DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0003705 and RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity and molecular function this GO :0003723 and RNA binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0006355 and regulation of transcription, this GO :0000978 : RNA polymerase II core promoter proximal region sequence-specific DNA binding, this GO :0000978 : RNA polymerase II core promoter proximal region sequence-specific DNA binding and also this GO :0000979 : RNA polymerase II core promoter sequence-specific DNA binding and also this GO :0000980 : RNA polymerase II distal enhancer sequence-specific DNA binding and also this GO :0000981 : sequence-specific DNA binding RNA polymerase II transcription factor activity and also this GO :0001047 : core promoter binding and also this GO :0001077 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and also this GO :0001078 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription and also this GO :0001085 : RNA polymerase II transcription factor binding and also this GO :0001205 : RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and also this GO :0003677 : DNA binding and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0003705 : RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity and also this GO :0003723 : RNA binding and also this GO :0005515 : protein binding and also this GO :0043565 : sequence-specific DNA binding and also this GO :0051525 : NFAT protein binding, this GO :0000979 : RNA polymerase II core promoter sequence-specific DNA binding, this GO :0000980 : RNA polymerase II distal enhancer sequence-specific DNA binding, this GO :0000981 : sequence-specific DNA binding RNA polymerase II transcription factor activity, this GO :0001047 : core promoter binding, this GO :0001077 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, this GO :0001078 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, this GO :0001085 : RNA polymerase II transcription factor binding, this GO :0001205 : RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, this GO :0003677 : DNA binding, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0003705 : RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, this GO :0003723 : RNA binding, this GO :0005515 : protein binding, this GO :0043565 : sequence-specific DNA binding, this GO :0051525 : NFAT protein binding, 1 and SFPI1 and SPI-1 and SPI-A, 58934 and IDBG-637435 and ENSBTAG00000021709 and 507100, spleen focus forming virus (SFFV) proviral integration oncogene spi1 |
| Identity: |
11241 |
| Gene: |
SPI1 |
More about : SPI1 |
| Long gene name: |
Spi-1 proto-oncogene |
| Synonyms gene name: |
spleen focus forming virus (SFFV) proviral integration oncogene |
| Synonyms: |
PU, 1 SPI-A OF SFPI1 SPI-1 |
| Synonyms name: |
hematopoietic transcription factor PU, 1 31 kDa transforming protein |
| Locus: |
11p11, 2 |
| Discovery year: |
1988-07-04 |
| GenBank acession: |
X52056 |
| Entrez gene record: |
6688 |
| Pubmed identfication: |
1693183 |
| RefSeq identity: |
NM_003120 |
| Classification: |
ETS transcription factor family |
| Havana BLAST/BLAT: |
OTTHUMG00000150150 |