| Alternative name 1: |
Clone: 3A12, Mab anti-, NFATC3 |
| Alternative name 2: |
Clone: 3A12, Mab antibody-, NFATC3 |
| Alternative name 3: |
Clone: 3A12, Mab antibody-, NFATC3 |
| Alternative name 4: |
anti-NFATC3 Clone: 3A12 |
| Alternative name 5: |
NFATC3 Clone: 3A12 |
| Clonality: |
Monoclonal Antibody |
| Description: |
Amongst the advantages of the monoclonal antibodies are: the fact that while the hybridoma takes a bit longer to be produced, If used correctly and according the protocol, in comparison to the polyclonal antibodies monoclonal antibodies are highly specific to a given epitope and can be used in applications where specific targeting is required, once the line is ready there is virtually an endless supply of these antibodie throughout time with little to no variations in recognition sites of the antigen in different batches, this antibody will provide excellent and reproducible results with guaranteed success for the tested and confirmed applications, This is a monoclonal antibody which is greatly purified and with high binding affinity for the antigen that it is risen against |
| Storage and handling: |
Antibodies in a liquid form can be shipped and stored for a short period of time at +4 degrees Celsius, antibodies that are lyophilized can be transported at ambient temperature and stored for short terms at +4 degrees Celsius, for long term storage (up to one year) 25-50% glycerol or ethylene glycol should be added and then the container has to be stored at -20°, for longer periods - at -20 , C, Generally |
| Advisory: |
For antibodies in a liquid form or reconstituted lyophilized antibodies small amounts of the soultion could be captured on the cap or the walls of the container, Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom, To keep the quality and the affinity of the antibody cycles of freezing and thawing should be avoided |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| French translation: |
anticorps |
| Gene target: |
Monoclonal 3A12, NFATC3 |
| Short name: |
Mouse Monoclonal antibody- Clone: 3A12, NFATC3 |
| Technique: |
Monoclonals or monoclonal antibodies, mouses, Mouse |
| Species: |
Mouses, Mouse |
| Alternative name: |
Mouse monoclonal (Antibody to)-, calcineurin-dependent 3, clonality: 3A12, cytoplasmic, nuclear factor on activated T-cells |
| Alternative technique: |
murine |
| Alternative to gene target: |
BT, DNA-templated and biological process this GO :0006357 and regulation of transcription from RNA polymerase II promoter and biological process this GO :0006366 and transcription from RNA polymerase II promoter and biological process this GO :0006954 and inflammatory response and biological process this GO :0007507 and heart development and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0045087 and innate immune response and biological process this GO :0045333 and cellular respiration and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0051145 and smooth muscle cell differentiation and biological process this GO :0055001 and muscle cell development and biological process this GO :0071277 and cellular response to calcium ion and biological process this GO :0071285 and cellular response to lithium ion and biological process, NFAT4 and NFATX, NFATC3 and IDBG-38028 and ENSG00000072736 and 4775, Nfatc3 and IDBG-189544 and ENSMUSG00000031902 and 18021, calcineurin-dependent 3, cytoplasmic, nuclei, protein binding, this GO :0000978 and RNA polymerase II core promoter proximal region sequence-specific DNA binding and molecular function this GO :0001077 and RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and molecular function this GO :0001569 and patterning of blood vessels and biological process this GO :0003677 and DNA binding and molecular function this GO :0003682 and chromatin binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005730 and nucleolus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006355 and regulation of transcription, this GO :0000978 : RNA polymerase II core promoter proximal region sequence-specific DNA binding, this GO :0000978 : RNA polymerase II core promoter proximal region sequence-specific DNA binding and also this GO :0001077 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and also this GO :0003677 : DNA binding and also this GO :0003682 : chromatin binding and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0005515 : protein binding, this GO :0001077 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, this GO :0003677 : DNA binding, this GO :0003682 : chromatin binding, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0005515 : protein binding, 105181 and IDBG-634110 and ENSBTAG00000004368 and 541127, nuclear factor of activated T-cells |
| Identity: |
7777 |
| Gene: |
NFATC3 |
More about : NFATC3 |
| Long gene name: |
nuclear factor of activated T-cells 3 |
| Synonyms gene name: |
calcineurin-dependent 3 , cytoplasmic, nuclear factor of activated T-cells |
| Synonyms: |
NFAT4 NFATX |
| Locus: |
16q22, 1 |
| Discovery year: |
1994-11-16 |
| GenBank acession: |
L41067 |
| Entrez gene record: |
4775 |
| Pubmed identfication: |
7749981 |
| RefSeq identity: |
NM_004555 |
| Classification: |
Nuclear factors of activated T-cells |
| Havana BLAST/BLAT: |
OTTHUMG00000137555 |