| Alternative name 1: |
Clone: 2H8, Mab anti-, ID3 |
| Alternative name 2: |
Clone: 2H8, Mab antibody-, ID3 |
| Alternative name 3: |
Clone: 2H8, Mab antibody-, ID3 |
| Alternative name 4: |
anti-ID3 Clone: 2H8 |
| Alternative name 5: |
ID3 Clone: 2H8 |
| Clonality: |
Monoclonal Antibody |
| Description: |
Amongst the advantages of the monoclonal antibodies are: the fact that while the hybridoma takes a bit longer to be produced, If used correctly and according the protocol, in comparison to the polyclonal antibodies monoclonal antibodies are highly specific to a given epitope and can be used in applications where specific targeting is required, once the line is ready there is virtually an endless supply of these antibodie throughout time with little to no variations in recognition sites of the antigen in different batches, this antibody will provide excellent and reproducible results with guaranteed success for the tested and confirmed applications, This is a monoclonal antibody which is greatly purified and with high binding affinity for the antigen that it is risen against |
| Storage and handling: |
Antibodies in a liquid form can be shipped and stored for a short period of time at +4 degrees Celsius, antibodies that are lyophilized can be transported at ambient temperature and stored for short terms at +4 degrees Celsius, for long term storage (up to one year) 25-50% glycerol or ethylene glycol should be added and then the container has to be stored at -20°, for longer periods - at -20 , C, Generally |
| Advisory: |
For antibodies in a liquid form or reconstituted lyophilized antibodies small amounts of the soultion could be captured on the cap or the walls of the container, Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom, To keep the quality and the affinity of the antibody cycles of freezing and thawing should be avoided |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| French translation: |
anticorps |
| Gene target: |
Monoclonal 2H8, ID3 |
| Short name: |
Mouse Monoclonal antibody- Clone: 2H8, ID3 |
| Technique: |
Monoclonals or monoclonal antibodies, mouses, Mouse |
| Species: |
Mouses, Mouse |
| Alternative name: |
Mouse monoclonal (Antibody to)-, clonality: 2H8, dominant negative helix-loop-helix protein, inhibitor on Desoxyribonucleic acid binding 3 |
| Alternative technique: |
murine |
| Alternative to gene target: |
DNA-templated and biological process this GO :0007275 and multicellular organismal development and biological process this GO :0007417 and central nervous system development and biological process this GO :0007507 and heart development and biological process this GO :0007517 and muscle organ development and biological process this GO :0008134 and transcription factor binding and molecular function this GO :0009611 and response to wounding and biological process this GO :0015630 and microtubule cytoskeleton and cellular component this GO :0019904 and protein domain specific binding and molecular function this GO :0030182 and neuron differentiation and biological process this GO :0030855 and epithelial cell differentiation and biological process this GO :0030903 and notochord development and biological process this GO :0042476 and odontogenesis and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043433 and negative regulation of sequence-specific DNA binding transcription factor activity and biological process this GO :0045662 and negative regulation of myoblast differentiation and biological process this GO :0045668 and negative regulation of osteoblast differentiation and biological process this GO :0045892 and negative regulation of transcription, DNA-templated and biological process this GO :0046983 and protein dimerization activity and molecular function this GO :0051726 and regulation of cell cycle and biological process, ID3 and IDBG-645454 and ENSBTAG00000030425 and 538690, ID3 and IDBG-93963 and ENSG00000117318 and 3399, Id3 and IDBG-197682 and ENSMUSG00000007872 and 15903, bHLHb25 and HEIR-1, dominant negative helix-loop-helix protein, nuclei, protein dimerization activity, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0001656 and metanephros development and biological process this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0003714 and transcription corepressor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006275 and regulation of DNA replication and biological process this GO :0006351 and transcription, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0003714 : transcription corepressor activity and also this GO :0005515 : protein binding and also this GO :0008134 : transcription factor binding and also this GO :0019904 : protein domain specific binding and also this GO :0046983 : protein dimerization activity, this GO :0003714 : transcription corepressor activity, this GO :0005515 : protein binding, this GO :0008134 : transcription factor binding, this GO :0019904 : protein domain specific binding, this GO :0046983 : protein dimerization activity, inhibitor of DNA binding 3 |
| Identity: |
5362 |
| Gene: |
ID3 |
More about : ID3 |
| Long gene name: |
HLH protein , inhibitor of DNA binding 3 |
| Synonyms gene name: |
dominant negative helix-loop-helix protein , inhibitor of DNA binding 3 |
| Synonyms: |
HEIR-1 bHLHb25 |
| Synonyms name: |
inhibitor of differentiation 3 |
| Locus: |
1p36, 12 |
| Discovery year: |
1994-12-19 |
| GenBank acession: |
X69111 |
| Entrez gene record: |
3399 |
| Pubmed identfication: |
1628620 |
| RefSeq identity: |
NM_002167 |
| Classification: |
Basic helix-loop-helix proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000003229 |