| Alternative name 1: |
Clone: 3A3, Mab anti-, HES1 |
| Alternative name 2: |
Clone: 3A3, Mab antibody-, HES1 |
| Alternative name 3: |
Clone: 3A3, Mab antibody-, HES1 |
| Alternative name 4: |
anti-HES1 Clone: 3A3 |
| Alternative name 5: |
HES1 Clone: 3A3 |
| Clonality: |
Monoclonal Antibody |
| Description: |
Amongst the advantages of the monoclonal antibodies are: the fact that while the hybridoma takes a bit longer to be produced, If used correctly and according the protocol, in comparison to the polyclonal antibodies monoclonal antibodies are highly specific to a given epitope and can be used in applications where specific targeting is required, once the line is ready there is virtually an endless supply of these antibodie throughout time with little to no variations in recognition sites of the antigen in different batches, this antibody will provide excellent and reproducible results with guaranteed success for the tested and confirmed applications, This is a monoclonal antibody which is greatly purified and with high binding affinity for the antigen that it is risen against |
| Storage and handling: |
Antibodies in a liquid form can be shipped and stored for a short period of time at +4 degrees Celsius, antibodies that are lyophilized can be transported at ambient temperature and stored for short terms at +4 degrees Celsius, for long term storage (up to one year) 25-50% glycerol or ethylene glycol should be added and then the container has to be stored at -20°, for longer periods - at -20 , C, Generally |
| Advisory: |
For antibodies in a liquid form or reconstituted lyophilized antibodies small amounts of the soultion could be captured on the cap or the walls of the container, Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom, To keep the quality and the affinity of the antibody cycles of freezing and thawing should be avoided |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| French translation: |
anticorps |
| Gene target: |
Monoclonal 3A3, HES1 |
| Short name: |
Mouse Monoclonal antibody- Clone: 3A3, HES1 |
| Technique: |
Monoclonals or monoclonal antibodies, mouses, Mouse |
| Species: |
Mouses, Mouse |
| Alternative name: |
(Drosophila), Mouse monoclonal (Antibody to)-, clonality: 3A3, hairy and enhancer on split 1 |
| Alternative technique: |
murine |
| Alternative to gene target: |
(Drosophila), DNA-templated and biological process this GO :0006357 and regulation of transcription from RNA polymerase II promoter and biological process this GO :0006366 and transcription from RNA polymerase II promoter and biological process this GO :0006461 and protein complex assembly and biological process this GO :0007155 and cell adhesion and biological process this GO :0007219 and Notch signaling pathway and biological process this GO :0007224 and smoothened signaling pathway and biological process this GO :0007262 and STAT protein import into nucleus and biological process this GO :0007389 and pattern specification process and biological process this GO :0007399 and nervous system development and biological process this GO :0008134 and transcription factor binding and molecular function this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0016477 and cell migration and biological process this GO :0021537 and telencephalon development and biological process this GO :0021555 and midbrain-hindbrain boundary morphogenesis and biological process this GO :0021557 and oculomotor nerve development and biological process this GO :0021558 and trochlear nerve development and biological process this GO :0021575 and hindbrain morphogenesis and biological process this GO :0021861 and forebrain radial glial cell differentiation and biological process this GO :0021915 and neural tube development and biological process this GO :0021983 and pituitary gland development and biological process this GO :0021984 and adenohypophysis development and biological process this GO :0030324 and lung development and biological process this GO :0030513 and positive regulation of BMP signaling pathway and biological process this GO :0030901 and midbrain development and biological process this GO :0031016 and pancreas development and biological process this GO :0031018 and endocrine pancreas development and biological process this GO :0035019 and somatic stem cell maintenance and biological process this GO :0035909 and aorta morphogenesis and biological process this GO :0035910 and ascending aorta morphogenesis and biological process this GO :0042102 and positive regulation of T cell proliferation and biological process this GO :0042491 and auditory receptor cell differentiation and biological process this GO :0042517 and positive regulation of tyrosine phosphorylation of Stat3 protein and biological process this GO :0042668 and auditory receptor cell fate determination and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0042826 and histone deacetylase binding and molecular function this GO :0043388 and positive regulation of DNA binding and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0045165 and cell fate commitment and biological process this GO :0045596 and negative regulation of cell differentiation and biological process this GO :0045598 and regulation of fat cell differentiation and biological process this GO :0045608 and negative regulation of auditory receptor cell differentiation and biological process this GO :0045665 and negative regulation of neuron differentiation and biological process this GO :0045747 and positive regulation of Notch signaling pathway and biological process this GO :0045892 and negative regulation of transcription, DNA-templated and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0045977 and positive regulation of mitotic cell cycle, HES1 and IDBG-634294 and ENSBTAG00000000569 and 539547, HES1 and IDBG-70185 and ENSG00000114315 and 3280, Hes1 and IDBG-151888 and ENSMUSG00000022528 and 15205, N-box binding, bHLHb39 and HES-1 and HHL and HRY, embryonic and biological process this GO :0046331 and lateral inhibition and biological process this GO :0046427 and positive regulation of JAK-STAT cascade and biological process this GO :0046983 and protein dimerization activity and molecular function this GO :0048469 and cell maturation and biological process this GO :0048505 and regulation of timing of cell differentiation and biological process this GO :0048538 and thymus development and biological process this GO :0048667 and cell morphogenesis involved in neuron differentiation and biological process this GO :0048711 and positive regulation of astrocyte differentiation and biological process this GO :0048715 and negative regulation of oli this GO dendrocyte differentiation and biological process this GO :0048844 and artery morphogenesis and biological process this GO :0050767 and regulation of neurogenesis and biological process this GO :0060164 and regulation of timing of neuron differentiation and biological process this GO :0060253 and negative regulation of glial cell proliferation and biological process this GO :0060412 and ventricular septum morphogenesis and biological process this GO :0060675 and ureteric bud morphogenesis and biological process this GO :0060716 and labyrinthine layer blood vessel development and biological process this GO :0061009 and common bile duct development and biological process this GO :0061106 and negative regulation of stomach neuroendocrine cell differentiation and biological process this GO :0061309 and cardiac neural crest cell development involved in outflow tract morphogenesis and biological process this GO :0061626 and pharyngeal arch artery morphogenesis and biological process this GO :0071820 and N-box binding and molecular function this GO :0072012 and glomerulus vasculature development and biological process this GO :0072049 and comma-shaped body morphogenesis and biological process this GO :0072050 and S-shaped body morphogenesis and biological process this GO :0072141 and renal interstitial cell development and biological process this GO :0072282 and metanephric nephron tubule morphogenesis and biological process this GO :0090102 and cochlea development and biological process this GO :0097084 and vascular smooth muscle cell development and biological process this GO :0097150 and neuronal stem cell maintenance and biological process this GO :2000227 and negative regulation of pancreatic A cell differentiation and biological process this GO :2000737 and negative regulation of stem cell differentiation and biological process this GO :2000974 and negative regulation of pro-B cell differentiation and biological process this GO :2000978 and negative regulation of forebrain neuron differentiation and biological process this GO :2000981 and negative regulation of inner ear receptor cell differentiation and biological process, nuclei, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0000981 and sequence-specific DNA binding RNA polymerase II transcription factor activity and molecular function this GO :0001078 and RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription and molecular function this GO :0001701 and in utero embryonic development and biological process this GO :0001889 and liver development and biological process this GO :0003143 and embryonic heart tube morphogenesis and biological process this GO :0003151 and outflow tract morphogenesis and biological process this GO :0003266 and regulation of secondary heart field cardioblast proliferation and biological process this GO :0003281 and ventricular septum development and biological process this GO :0003677 and DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006355 and regulation of transcription, this GO :0000981 : sequence-specific DNA binding RNA polymerase II transcription factor activity, this GO :0000981 : sequence-specific DNA binding RNA polymerase II transcription factor activity and also this GO :0001078 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription and also this GO :0003677 : DNA binding and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0005515 : protein binding and also this GO :0008134 : transcription factor binding and also this GO :0042803 : protein homodimerization activity and also this GO :0042826 : histone deacetylase binding and also this GO :0043565 : sequence-specific DNA binding and also this GO :0046983 : protein dimerization activity and also this GO :0071820 : N-box binding, this GO :0001078 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, this GO :0003677 : DNA binding, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0005515 : protein binding, this GO :0008134 : transcription factor binding, this GO :0042803 : protein homodimerization activity, this GO :0042826 : histone deacetylase binding, this GO :0043565 : sequence-specific DNA binding, this GO :0046983 : protein dimerization activity, this GO :0071820 : N-box binding, hairy and enhancer of split 1 |
| Identity: |
5192 |
| Gene: |
HES1 |
More about : HES1 |
| Long gene name: |
hes family bHLH transcription factor 1 |
| Synonyms gene: |
HRY |
| Synonyms gene name: |
(Drosophila) , hairy homolog (Drosophila) hairy and enhancer of split 1 |
| Synonyms: |
FLJ20408 HES-1 Hes1 bHLHb39 |
| Locus: |
3q29 |
| Discovery year: |
1993-09-21 |
| GenBank acession: |
L19314 |
| Entrez gene record: |
3280 |
| Pubmed identfication: |
8020957 |
| Classification: |
Basic helix-loop-helix proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000155984 |