| Alternative name 1: |
Clone: 6G12, Mab anti-, TYK2 |
| Alternative name 2: |
Clone: 6G12, Mab antibody-, TYK2 |
| Alternative name 3: |
Clone: 6G12, Mab antibody-, TYK2 |
| Alternative name 4: |
anti-TYK2 Clone: 6G12 |
| Alternative name 5: |
TYK2 Clone: 6G12 |
| Clonality: |
Monoclonal Antibody |
| Description: |
Amongst the advantages of the monoclonal antibodies are: the fact that while the hybridoma takes a bit longer to be produced, If used correctly and according the protocol, in comparison to the polyclonal antibodies monoclonal antibodies are highly specific to a given epitope and can be used in applications where specific targeting is required, once the line is ready there is virtually an endless supply of these antibodie throughout time with little to no variations in recognition sites of the antigen in different batches, this antibody will provide excellent and reproducible results with guaranteed success for the tested and confirmed applications, This is a monoclonal antibody which is greatly purified and with high binding affinity for the antigen that it is risen against |
| Storage and handling: |
Antibodies in a liquid form can be shipped and stored for a short period of time at +4 degrees Celsius, antibodies that are lyophilized can be transported at ambient temperature and stored for short terms at +4 degrees Celsius, for long term storage (up to one year) 25-50% glycerol or ethylene glycol should be added and then the container has to be stored at -20°, for longer periods - at -20 , C, Generally |
| Advisory: |
For antibodies in a liquid form or reconstituted lyophilized antibodies small amounts of the soultion could be captured on the cap or the walls of the container, Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom, To keep the quality and the affinity of the antibody cycles of freezing and thawing should be avoided |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| French translation: |
anticorps |
| Gene target: |
Monoclonal 6G12, TYK2 |
| Short name: |
Mouse Monoclonal antibody- Clone: 6G12, TYK2 |
| Technique: |
Monoclonals or monoclonal antibodies, mouses, Mouse |
| Species: |
Mouses, Mouse |
| Alternative name: |
Mouse monoclonal (Antibody to)-, clonality: 6G12, tyrosine kinase 2 |
| Alternative technique: |
murine |
| Alternative to gene target: |
BT, IMD35 and JTK1, TYK2 and IDBG-27182 and ENSG00000105397 and 7297, Tyk2 and IDBG-139044 and ENSMUSG00000032175 and 54721, nuclei, this GO :0004672 and protein kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0004715 and non-membrane spanning protein tyrosine kinase activity and molecular function this GO :0005131 and growth hormone receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005856 and cytoskeleton and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0016020 and membrane and cellular component this GO :0016772 and transferase activity, this GO :0004672 : protein kinase activity, this GO :0004672 : protein kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0004715 : non-membrane spanning protein tyrosine kinase activity and also this GO :0005131 : growth hormone receptor binding and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0016772 : transferase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0004715 : non-membrane spanning protein tyrosine kinase activity, this GO :0005131 : growth hormone receptor binding, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0016772 : transferase activity, this GO :0031702 : type 1 angiotensin receptor binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0031702 : type 1 angiotensin receptor binding, transferring phosphorus-containing groups and molecular function this GO :0018108 and peptidyl-tyrosine phosphorylation and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0031702 and type 1 angiotensin receptor binding and molecular function this GO :0035556 and intracellular signal transduction and biological process this GO :0045087 and innate immune response and biological process this GO :0060337 and type I interferon signaling pathway and biological process this GO :0060338 and regulation of type I interferon-mediated signaling pathway and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, 23803 and IDBG-643269 and ENSBTAG00000011698 and 512484, tyrosine kinase 2 |
| Identity: |
12440 |
| Gene: |
TYK2 |
More about : TYK2 |
| Long gene name: |
tyrosine kinase 2 |
| Synonyms: |
JTK1 |
| Locus: |
19p13, 2 |
| Discovery year: |
1990-09-10 |
| Entrez gene record: |
7297 |
| Pubmed identfication: |
2156206 |
| Classification: |
FERM domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000166373 |
| Locus Specific Databases: |
TYK2base: Mutation registry for TYK2 deficiency LRG_121 |