| Alternative name 1: |
Clone: 2D7, Mab anti-, SMAD5 |
| Alternative name 2: |
Clone: 2D7, Mab antibody-, SMAD5 |
| Alternative name 3: |
Clone: 2D7, Mab antibody-, SMAD5 |
| Alternative name 4: |
anti-SMAD5 Clone: 2D7 |
| Alternative name 5: |
SMAD5 Clone: 2D7 |
| Clonality: |
Monoclonal Antibody |
| Description: |
Amongst the advantages of the monoclonal antibodies are: the fact that while the hybridoma takes a bit longer to be produced, If used correctly and according the protocol, in comparison to the polyclonal antibodies monoclonal antibodies are highly specific to a given epitope and can be used in applications where specific targeting is required, once the line is ready there is virtually an endless supply of these antibodie throughout time with little to no variations in recognition sites of the antigen in different batches, this antibody will provide excellent and reproducible results with guaranteed success for the tested and confirmed applications, This is a monoclonal antibody which is greatly purified and with high binding affinity for the antigen that it is risen against |
| Storage and handling: |
Antibodies in a liquid form can be shipped and stored for a short period of time at +4 degrees Celsius, antibodies that are lyophilized can be transported at ambient temperature and stored for short terms at +4 degrees Celsius, for long term storage (up to one year) 25-50% glycerol or ethylene glycol should be added and then the container has to be stored at -20°, for longer periods - at -20 , C, Generally |
| Advisory: |
For antibodies in a liquid form or reconstituted lyophilized antibodies small amounts of the soultion could be captured on the cap or the walls of the container, Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom, To keep the quality and the affinity of the antibody cycles of freezing and thawing should be avoided |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| French translation: |
anticorps |
| Gene target: |
Monoclonal 2D7, SMAD5 |
| Short name: |
Mouse Monoclonal antibody- Clone: 2D7, SMAD5 |
| Technique: |
Monoclonals or monoclonal antibodies, mouses, Mouse |
| Species: |
Mouses, Mouse |
| Alternative name: |
Mouse monoclonal (Antibody to)-, clonality: 2D7, SMAD family member 5 |
| Alternative technique: |
murine |
| Alternative to gene target: |
BT, DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006468 and protein phosphorylation and biological process this GO :0007165 and signal transduction and biological process this GO :0007179 and transforming growth factor beta receptor signaling pathway and biological process this GO :0007281 and germ cell development and biological process this GO :0009880 and embryonic pattern specification and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0030218 and erythrocyte differentiation and biological process this GO :0030509 and BMP signaling pathway and biological process this GO :0030618 and transforming growth factor beta receptor, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046872 and metal ion binding and molecular function this GO :0051216 and cartilage development and biological process this GO :0060048 and cardiac muscle contraction and biological process this GO :0060348 and bone development and biological process this GO :0071407 and cellular response to organic cyclic compound and biological process this GO :0071773 and cellular response to BMP stimulus and biological process this GO :1901522 and positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus and biological process, DWFC and JV5-1 and MADH5, SMAD5 and IDBG-45903 and ENSG00000113658 and 4090, Smad5 and IDBG-157537 and ENSMUSG00000021540 and 17129, nuclei, pathway-specific cytoplasmic mediator activity, pathway-specific cytoplasmic mediator activity and also this GO :0031625 : ubiquitin protein ligase binding and also this GO :0046872 : metal ion binding, pathway-specific cytoplasmic mediator activity and molecular function this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0035556 and intracellular signal transduction and biological process this GO :0043234 and protein complex and cellular component this GO :0045669 and positive regulation of osteoblast differentiation and biological process this GO :0045893 and positive regulation of transcription, this GO :0000979 and RNA polymerase II core promoter sequence-specific DNA binding and molecular function this GO :0001503 and ossification and biological process this GO :0001657 and ureteric bud development and biological process this GO :0001880 and Mullerian duct regression and biological process this GO :0002051 and osteoblast fate commitment and biological process this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005057 and receptor signaling protein activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005667 and transcription factor complex and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006351 and transcription, this GO :0000979 : RNA polymerase II core promoter sequence-specific DNA binding, this GO :0000979 : RNA polymerase II core promoter sequence-specific DNA binding and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0005057 : receptor signaling protein activity and also this GO :0005515 : protein binding and also this GO :0030618 : transforming growth factor beta receptor, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0005057 : receptor signaling protein activity, this GO :0005515 : protein binding, this GO :0030618 : transforming growth factor beta receptor, this GO :0031625 : ubiquitin protein ligase binding, this GO :0046872 : metal ion binding, transforming growth factor beta receptor, 69069 and IDBG-645857 and ENSBTAG00000021772 and 768050, SMAD family member 5 |
| Identity: |
6771 |
| Gene: |
SMAD5 |
More about : SMAD5 |
| Long gene name: |
SMAD family member 5 |
| Synonyms gene: |
MADH5 |
| Synonyms gene name: |
MAD, mothers against DPP homolog 5 (Drosophila) , mothers against decapentaplegic homolog 5 (Drosophila) SMAD |
| Synonyms: |
Dwfc JV5-1 |
| Locus: |
5q31, 1 |
| Discovery year: |
1997-07-01 |
| GenBank acession: |
U59913 |
| Entrez gene record: |
4090 |
| Pubmed identfication: |
8673135 |
| RefSeq identity: |
NM_005903 |
| Classification: |
SMAD family |
| Havana BLAST/BLAT: |
OTTHUMG00000163212 |