| Alternative name 1: |
Clone: 1B3, Mab anti-, PSMB8 |
| Alternative name 2: |
Clone: 1B3, Mab antibody-, PSMB8 |
| Alternative name 3: |
Clone: 1B3, Mab antibody-, PSMB8 |
| Alternative name 4: |
anti-PSMB8 Clone: 1B3 |
| Alternative name 5: |
PSMB8 Clone: 1B3 |
| Clonality: |
Monoclonal Antibody |
| Description: |
Amongst the advantages of the monoclonal antibodies are: the fact that while the hybridoma takes a bit longer to be produced, If used correctly and according the protocol, in comparison to the polyclonal antibodies monoclonal antibodies are highly specific to a given epitope and can be used in applications where specific targeting is required, once the line is ready there is virtually an endless supply of these antibodie throughout time with little to no variations in recognition sites of the antigen in different batches, this antibody will provide excellent and reproducible results with guaranteed success for the tested and confirmed applications, This is a monoclonal antibody which is greatly purified and with high binding affinity for the antigen that it is risen against |
| Storage and handling: |
Antibodies in a liquid form can be shipped and stored for a short period of time at +4 degrees Celsius, antibodies that are lyophilized can be transported at ambient temperature and stored for short terms at +4 degrees Celsius, for long term storage (up to one year) 25-50% glycerol or ethylene glycol should be added and then the container has to be stored at -20°, for longer periods - at -20 , C, Generally |
| Advisory: |
For antibodies in a liquid form or reconstituted lyophilized antibodies small amounts of the soultion could be captured on the cap or the walls of the container, Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom, To keep the quality and the affinity of the antibody cycles of freezing and thawing should be avoided |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| French translation: |
anticorps |
| Gene target: |
Monoclonal 1B3, PSMB8 |
| Short name: |
Mouse Monoclonal antibody- Clone: 1B3, PSMB8 |
| Technique: |
Monoclonals or monoclonal antibodies, mouses, Mouse |
| Species: |
Mouses, Mouse |
| Alternative name: |
8 (large multifunctional peptidase 7), Mouse monoclonal (Antibody to)-, b classification, clonality: 1B3, macropain) subunit, proteasome (prosome |
| Alternative technique: |
murine |
| Alternative to gene target: |
8 (large multifunctional peptidase 7), ALDD and D6S216 and D6S216E and JMP and LMP7 and NKJO and PSMB5i and RING10, PSMB8 and IDBG-628854 and ENSBTAG00000003039 and 282013, PSMB8 and IDBG-81522 and ENSG00000204264 and 5696, Psmb8 and IDBG-170702 and ENSMUSG00000024338 and 16913, TAP-dependent and biological process this GO :0004298 and threonine-type endopeptidase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005654 and nucleoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005839 and proteasome core complex and cellular component this GO :0006521 and regulation of cellular amino acid metabolic process and biological process this GO :0006915 and apoptotic process and biological process this GO :0006977 and DNA damage response, beta type, macropain) subunit, nuclei, protein binding, signal transduction by p53 class mediator resulting in cell cycle arrest and biological process this GO :0010467 and gene expression and biological process this GO :0016032 and viral process and biological process this GO :0016070 and RNA metabolic process and biological process this GO :0016071 and mRNA metabolic process and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0019882 and antigen processing and presentation and biological process this GO :0031145 and anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process and biological process this GO :0034641 and cellular nitrogen compound metabolic process and biological process this GO :0042590 and antigen processing and presentation of exogenous peptide antigen via MHC class I and biological process this GO :0042981 and regulation of apoptotic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0045444 and fat cell differentiation and biological process this GO :0051436 and negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle and biological process this GO :0051437 and positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle and biological process this GO :0051439 and regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle and biological process this GO :0051603 and proteolysis involved in cellular protein catabolic process and biological process this GO :0060337 and type I interferon signaling pathway and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :1990111 and spermatoproteasome complex and cellular component, this GO :0000082 and G1/S transition of mitotic cell cycle and biological process this GO :0000209 and protein polyubiquitination and biological process this GO :0000278 and mitotic cell cycle and biological process this GO :0000502 and proteasome complex and cellular component this GO :0002474 and antigen processing and presentation of peptide antigen via MHC class I and biological process this GO :0002479 and antigen processing and presentation of exogenous peptide antigen via MHC class I, this GO :0004298 : threonine-type endopeptidase activity, this GO :0004298 : threonine-type endopeptidase activity and also this GO :0005515 : protein binding, this GO :0005515 : protein binding, proteasome (prosome |
| Identity: |
9545 |
| Gene: |
PSMB8 |
More about : PSMB8 |
| Long gene name: |
proteasome subunit beta 8 |
| Synonyms gene: |
LMP7 |
| Synonyms gene name: |
8 , 8 (large multifunctional protease 7) large multifunctional peptidase 7 proteasome (prosome, beta type, beta type, macropain) subunit, macropain) subunit, proteasome (prosome |
| Synonyms: |
RING10 D6S216E PSMB5i beta5i |
| Locus: |
6p21, 32 |
| Discovery year: |
1992-06-25 |
| Entrez gene record: |
5696 |
| Pubmed identfication: |
1529427 10329130 |
| RefSeq identity: |
NM_148919 |
| Classification: |
Proteasome |
| Havana BLAST/BLAT: |
OTTHUMG00000031285 |