| Alternative name 1: |
Clone: 2E4, Mab anti-, IRF1 |
| Alternative name 2: |
Clone: 2E4, Mab antibody-, IRF1 |
| Alternative name 3: |
Clone: 2E4, Mab antibody-, IRF1 |
| Alternative name 4: |
anti-IRF1 Clone: 2E4 |
| Alternative name 5: |
IRF1 Clone: 2E4 |
| Clonality: |
Monoclonal Antibody |
| Description: |
Amongst the advantages of the monoclonal antibodies are: the fact that while the hybridoma takes a bit longer to be produced, If used correctly and according the protocol, in comparison to the polyclonal antibodies monoclonal antibodies are highly specific to a given epitope and can be used in applications where specific targeting is required, once the line is ready there is virtually an endless supply of these antibodie throughout time with little to no variations in recognition sites of the antigen in different batches, this antibody will provide excellent and reproducible results with guaranteed success for the tested and confirmed applications, This is a monoclonal antibody which is greatly purified and with high binding affinity for the antigen that it is risen against |
| Storage and handling: |
Antibodies in a liquid form can be shipped and stored for a short period of time at +4 degrees Celsius, antibodies that are lyophilized can be transported at ambient temperature and stored for short terms at +4 degrees Celsius, for long term storage (up to one year) 25-50% glycerol or ethylene glycol should be added and then the container has to be stored at -20°, for longer periods - at -20 , C, Generally |
| Advisory: |
For antibodies in a liquid form or reconstituted lyophilized antibodies small amounts of the soultion could be captured on the cap or the walls of the container, Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom, To keep the quality and the affinity of the antibody cycles of freezing and thawing should be avoided |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| French translation: |
anticorps |
| Gene target: |
Monoclonal 2E4, IRF1 |
| Short name: |
Mouse Monoclonal antibody- Clone: 2E4, IRF1 |
| Technique: |
Monoclonals or monoclonal antibodies, mouses, Mouse |
| Species: |
Mouses, Mouse |
| Alternative name: |
Mouse monoclonal (Antibody to)-, clonality: 2E4, interferon regulatory factor 1 |
| Alternative technique: |
murine |
| Alternative to gene target: |
DNA-templated and biological process this GO :0006366 and transcription from RNA polymerase II promoter and biological process this GO :0006915 and apoptotic process and biological process this GO :0007050 and cell cycle arrest and biological process this GO :0007596 and blood coagulation and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0010468 and regulation of gene expression and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0032481 and positive regulation of type I interferon production and biological process this GO :0032728 and positive regulation of interferon-beta production and biological process this GO :0034124 and regulation of MyD88-dependent toll-like receptor signaling pathway and biological process this GO :0035458 and cellular response to interferon-beta and biological process this GO :0043374 and CD8-positive, DNA-templated and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0051607 and defense response to virus and biological process this GO :0051726 and regulation of cell cycle and biological process this GO :0060333 and interferon-gamma-mediated signaling pathway and biological process this GO :0060337 and type I interferon signaling pathway and biological process this GO :0071260 and cellular response to mechanical stimulus and biological process this GO :2000564 and regulation of CD8-positive, IRF-1 and MAR, IRF1 and IDBG-42125 and ENSG00000125347 and 3659, IRF1 and IDBG-644680 and ENSBTAG00000031231 and 337917, Irf1 and IDBG-172251 and ENSMUSG00000018899 and 16362, alpha-beta T cell differentiation and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0045084 and positive regulation of interleukin-12 biosynthetic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045088 and regulation of innate immune response and biological process this GO :0045590 and negative regulation of regulatory T cell differentiation and biological process this GO :0045892 and negative regulation of transcription, alpha-beta T cell proliferation and biological process, nuclei, sequence-specific DNA binding, this GO :0000790 and nuclear chromatin and cellular component this GO :0000975 and regulatory region DNA binding and molecular function this GO :0000978 and RNA polymerase II core promoter proximal region sequence-specific DNA binding and molecular function this GO :0002819 and regulation of adaptive immune response and biological process this GO :0003677 and DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006355 and regulation of transcription, this GO :0000975 : regulatory region DNA binding, this GO :0000975 : regulatory region DNA binding and also this GO :0000978 : RNA polymerase II core promoter proximal region sequence-specific DNA binding and also this GO :0003677 : DNA binding and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0005515 : protein binding and also this GO :0043565 : sequence-specific DNA binding, this GO :0000978 : RNA polymerase II core promoter proximal region sequence-specific DNA binding, this GO :0003677 : DNA binding, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0005515 : protein binding, this GO :0043565 : sequence-specific DNA binding, 789216, interferon regulatory factor 1 |
| Identity: |
6116 |
| Gene: |
IRF1 |
More about : IRF1 |
| Long gene name: |
interferon regulatory factor 1 |
| Synonyms: |
MAR |
| Synonyms name: |
interferon regulatory factor-1 |
| Locus: |
5q31, 1 |
| Discovery year: |
1991-05-09 |
| Entrez gene record: |
3659 |
| Pubmed identfication: |
2726461 1680796 |
| RefSeq identity: |
NM_002198 |
| Havana BLAST/BLAT: |
OTTHUMG00000059497 |