| Alternative name 1: |
Clone: 1F5, Mab anti-, GRN |
| Alternative name 2: |
Clone: 1F5, Mab antibody-, GRN |
| Alternative name 3: |
Clone: 1F5, Mab antibody-, GRN |
| Alternative name 4: |
anti-GRN Clone: 1F5 |
| Alternative name 5: |
GRN Clone: 1F5 |
| Clonality: |
Monoclonal Antibody |
| Description: |
Amongst the advantages of the monoclonal antibodies are: the fact that while the hybridoma takes a bit longer to be produced, If used correctly and according the protocol, in comparison to the polyclonal antibodies monoclonal antibodies are highly specific to a given epitope and can be used in applications where specific targeting is required, once the line is ready there is virtually an endless supply of these antibodie throughout time with little to no variations in recognition sites of the antigen in different batches, this antibody will provide excellent and reproducible results with guaranteed success for the tested and confirmed applications, This is a monoclonal antibody which is greatly purified and with high binding affinity for the antigen that it is risen against |
| Storage and handling: |
Antibodies in a liquid form can be shipped and stored for a short period of time at +4 degrees Celsius, antibodies that are lyophilized can be transported at ambient temperature and stored for short terms at +4 degrees Celsius, for long term storage (up to one year) 25-50% glycerol or ethylene glycol should be added and then the container has to be stored at -20°, for longer periods - at -20 , C, Generally |
| Advisory: |
For antibodies in a liquid form or reconstituted lyophilized antibodies small amounts of the soultion could be captured on the cap or the walls of the container, Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom, To keep the quality and the affinity of the antibody cycles of freezing and thawing should be avoided |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| French translation: |
anticorps |
| Gene target: |
Monoclonal 1F5, GRN |
| Short name: |
Mouse Monoclonal antibody- Clone: 1F5, GRN |
| Technique: |
Monoclonals or monoclonal antibodies, mouses, Mouse |
| Species: |
Mouses, Mouse |
| Alternative name: |
Mouse monoclonal (Antibody to)-, clonality: 1F5, granulin |
| Alternative technique: |
murine |
| Alternative to gene target: |
CLN11 and GEP and GP88 and PCDGF and PEPI and PGRN, Extracellular, GRN and IDBG-53782 and ENSG00000030582 and 2896, GRN and IDBG-640956 and ENSBTAG00000018823 and 767942, Grn and IDBG-212642 and ENSMUSG00000034708 and 14824, poly(A) RNA binding, this GO :0001835 and blastocyst hatching and biological process this GO :0005125 and cytokine activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0007165 and signal transduction and biological process this GO :0007566 and embryo implantation and biological process this GO :0008083 and growth factor activity and molecular function this GO :0008219 and cell death and biological process this GO :0043231 and intracellular membrane-bounded organelle and cellular component this GO :0044822 and poly(A) RNA binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0050679 and positive regulation of epithelial cell proliferation and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0005125 : cytokine activity, this GO :0005125 : cytokine activity and also this GO :0005515 : protein binding and also this GO :0008083 : growth factor activity and also this GO :0044822 : poly(A) RNA binding, this GO :0005515 : protein binding, this GO :0008083 : growth factor activity, this GO :0044822 : poly(A) RNA binding, granulin |
| Identity: |
4601 |
| Gene: |
GRN |
More about : GRN |
| Long gene name: |
granulin precursor |
| Synonyms: |
PCDGF PGRN CLN11 |
| Synonyms name: |
progranulin |
| Locus: |
17q21, 31 |
| Discovery year: |
1992-11-30 |
| GenBank acession: |
M75161 |
| Entrez gene record: |
2896 |
| Pubmed identfication: |
1417868 9826678 |
| RefSeq identity: |
NM_002087 |
| Havana BLAST/BLAT: |
OTTHUMG00000181816 |
| Locus Specific Databases: |
LRG_661 |