| Alternative name 1: |
Clone: 4D2, Mab anti-, DSC3 |
| Alternative name 2: |
Clone: 4D2, Mab antibody-, DSC3 |
| Alternative name 3: |
Clone: 4D2, Mab antibody-, DSC3 |
| Alternative name 4: |
anti-DSC3 Clone: 4D2 |
| Alternative name 5: |
DSC3 Clone: 4D2 |
| Clonality: |
Monoclonal Antibody |
| Description: |
Amongst the advantages of the monoclonal antibodies are: the fact that while the hybridoma takes a bit longer to be produced, If used correctly and according the protocol, in comparison to the polyclonal antibodies monoclonal antibodies are highly specific to a given epitope and can be used in applications where specific targeting is required, once the line is ready there is virtually an endless supply of these antibodie throughout time with little to no variations in recognition sites of the antigen in different batches, this antibody will provide excellent and reproducible results with guaranteed success for the tested and confirmed applications, This is a monoclonal antibody which is greatly purified and with high binding affinity for the antigen that it is risen against |
| Storage and handling: |
Antibodies in a liquid form can be shipped and stored for a short period of time at +4 degrees Celsius, antibodies that are lyophilized can be transported at ambient temperature and stored for short terms at +4 degrees Celsius, for long term storage (up to one year) 25-50% glycerol or ethylene glycol should be added and then the container has to be stored at -20°, for longer periods - at -20 , C, Generally |
| Advisory: |
For antibodies in a liquid form or reconstituted lyophilized antibodies small amounts of the soultion could be captured on the cap or the walls of the container, Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom, To keep the quality and the affinity of the antibody cycles of freezing and thawing should be avoided |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| French translation: |
anticorps |
| Gene target: |
Monoclonal 4D2, DSC3 |
| Short name: |
Mouse Monoclonal antibody- Clone: 4D2, DSC3 |
| Technique: |
Monoclonals or monoclonal antibodies, mouses, Mouse |
| Species: |
Mouses, Mouse |
| Alternative name: |
Mouse monoclonal (Antibody to)-, clonality: 4D2, desmocollin 3 |
| Alternative technique: |
murine |
| Alternative to gene target: |
CDHF3 and DSC and DSC1 and DSC2 and DSC4 and HT-CP, DSC3 and IDBG-1901 and ENSG00000134762 and 1825, DSC3 and IDBG-643774 and ENSBTAG00000015238 and 281129, Dsc3 and IDBG-129603 and ENSMUSG00000059898 and 13507, Extracellular, gamma-catenin binding, this GO :0001701 and in utero embryonic development and biological process this GO :0005509 and calcium ion binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005911 and cell-cell junction and cellular component this GO :0007155 and cell adhesion and biological process this GO :0007156 and homophilic cell adhesion and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0030057 and desmosome and cellular component this GO :0045295 and gamma-catenin binding and molecular function this GO :0050821 and protein stabilization and biological process, this GO :0005509 : calcium ion binding, this GO :0005509 : calcium ion binding and also this GO :0045295 : gamma-catenin binding, this GO :0045295 : gamma-catenin binding, desmocollin 3 |
| Identity: |
3036 |
| Gene: |
DSC2 |
More about : DSC2 |
| Long gene name: |
desmocollin 2 |
| Synonyms gene: |
DSC3 |
| Synonyms: |
CDHF2 |
| Locus: |
18q12, 1 |
| Discovery year: |
1997-05-29 |
| GenBank acession: |
X56807 |
| Entrez gene record: |
1824 |
| Pubmed identfication: |
7774948 |
| RefSeq identity: |
NM_004949 |
| Classification: |
Desmosomal cadherins |
| Havana BLAST/BLAT: |
OTTHUMG00000131981 |
| Locus Specific Databases: |
ARVD/C Genetic Variants Database LRG_400 |