| Also known as: |
Melanoma Associated Antigen |
| Other names: |
N/A, melanoma-associated antigen |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
NKI-C3 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Although the antigen is associated with melanomas, Extensive further heterogeneity was geneRated in the Golgi compartment and was shown to be dependent on the presence of complex type sugars, NKI/C3 originally was described as a marker for melanoma, Recently, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The antigen did show codistribution with Cathepsin D, The antigen is abundantly present in malignant melanomas, The antigen recognized by NKI/C-3 is a glycoprotein which appears as a broad band in SDS-PAGE, The antigen was shown to consist of a single protein backbone to which two or three, This particular antibody might cross react with speacies outside of the listed ones, and neuroendocrine tumors, it resurfaced as a marker to sepaRate cellular neurothekeoma from other dermal tumors in the differential diagnosis, it was not codistributed with the tyrosinase activity associated with melanogenesis, nevocellular nevi, whereas it has not been detectable in most other tissues, which is a marker for lysosomal functions, NKI/C-3 is a MAb which is directed anti a predominantly intracellular protein of Human melanoma cells, V-linked glycans were added cotranslationally |
| Form/Appearance: |
09% sodium azide, Each vial contains 100 ul 1 mg/ml purified monoclonal antibody in PBS containing 0 |
| Storage and shipping: |
or in small aliquots the antibody should be stored at -20 degrees Celsius, Store the antibody at +4 degrees Celsius |
| Tested applications:: |
Immunofluorescence (IF), Immunohistochemistry (IHC) (frozen), Immunohistochemistry (IHC) (paraffin), ELISA (EIA) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Melanoma Associated |
| Short name: |
Mouse Anti-Melanoma Associated Antigen Antibody |
| Technique: |
antibodies against human proteins, antibodies for, mouses, Antibody |
| Species: |
Mouses, Mouse |
| Alternative name: |
Mouse antibody to-Melanoma Associated protein (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
29641 |
| Gene: |
MUM1 |
More about : MUM1 |
| Long gene name: |
melanoma associated antigen (mutated) 1 |
| Synonyms: |
MUM-1 EXPAND1 |
| Locus: |
19p13, 3 |
| Discovery year: |
2004-02-12 |
| GenBank acession: |
AK075241 |
| Entrez gene record: |
84939 |
| Pubmed identfication: |
20347427 7644523 |
| RefSeq identity: |
NM_032853 |
| Classification: |
PWWP domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000180055 |