| Also known as: |
NCAM / CD56 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
123C3 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, Zebrafish, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
123C3 is internalized after binding to its antigen on SCLC cell lines, 123C3 recognizes an epitope in the NCAM exons 11-13 which is dependent on an intact conformation of the first fibronectin type-III homologous domain encoded by these exons, 123C3 stains NCAM which is present in small cell lung cancer and lung carcinoids, In addition, It also reacts with a number of non-small cell lung carcinomas and neuroendocrine and neuronal derived tissues, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, making it an excellent reagent for tumor imaging in xenograft models, 123C3 was defined as a cluster I antibody during the First International Workshop on Small Cell Lung Cancer (SCLC) Antibodies |
| Form/Appearance: |
09% sodium azide, Each vial contains 1ml of culture supernatant of monoclonal antibody containing 0 |
| Storage and shipping: |
or in small aliquots the antibody should be stored at -20 degrees Celsius, Store the antibody at +4 degrees Celsius |
| Tested applications:: |
Immunohistochemistry (IHC) (frozen), Immunohistochemistry (IHC) (paraffin), Western Blot (WB), Immunocytochemistry (IHC) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
NCAM / CD56 |
| Short name: |
Mouse Anti-NCAM / CD56 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, mouses, Antibody |
| Species: |
Mouses, Mouse |
| Alternative name: |
Mouse antibody to-NCAM / CD56 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
7656 |
| Gene: |
NCAM1 |
More about : NCAM1 |
| Long gene name: |
neural cell adhesion molecule 1 |
| Synonyms: |
NCAM CD56 |
| Locus: |
11q23, 2 |
| Discovery year: |
2001-06-22 |
| Entrez gene record: |
4684 |
| RefSeq identity: |
NM_000615 |
| Classification: |
Fibronectin type III domain containing I-set domain containing CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000167196 |