| Also known as: |
CD44 |
| Other names: |
CD44 antigen, CD44 antigen, CD44 molecule (Indian blood group), CDw44, ECMR-III, Epican, Extracellular matrix receptor III, GP90 lymphocyte homing/adhesion receptor, GP90 lymphocyte homing/adhesion receptor, HUTCH-I, Heparan sulfate proteoglycan, Hermes antigen, Hermes antigen, Hyaluronate receptor, PGP-1, Phagocytic glycoprotein 1, Phagocytic glycoprotein I, cell surface glycoprotein CD44, chondroitin sulfate proteoglycan 8, epican, extracellular matrix receptor III, hematopoietic cell E- and L-selectin ligand, heparan sulfate proteoglycan, homing function and Indian blood group system, hyaluronate receptor, phagocytic glycoprotein 1, CD44 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CD44 |
| Other gene names: |
CD44, CDW44, CSPG8, ECMR-III, ECMR-III, HCELL, HUTCH-I, IN, LHR, LHR, MC56, MDU2, MDU2, MDU3, MDU3, MIC4, MIC4, PGP-1, PGP-I, Pgp1, CD44 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
Rat IgG2a |
| Clone: |
KM81 |
| Host organism: |
Rat (Rattus norvegicus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Mouse (Mus musculus) |
| Specificity and cross-reactivity: |
Ly 24)), Pgp-1) (Mouse CD44 (Pgp-1, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, CD44 (Ly 24 |
| Form/Appearance: |
(Purified from bioreactor supernatant via Protein G Chromatography)), 0, 02% NaN3 and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/ml, FITC (FITC conjugated Ig buffered in PBS |
| Concentration: |
1 miligram per 1 mililiter, Antibody Concentration: 0 |
| Storage and shipping: |
Avoid freeze/thaw cycles, Avoid prolonged exposure to light, For long term storage, aliquot and freeze unused portion the antibody should be stored at -20 degrees Celsius, in volumes appropriate for single usage, Store the antibody at +4 degrees Celsius |
| Tested applications:: |
Immunohistochemistry (IHC) |
| Properties: |
FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, MBS mono FITC is highly sensitive to pH extremes, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, This MBS mono Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS |
| Conjugation: |
Anti-FITC Antibody |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
KM81) IgG2a), CD44 |
| Short name: |
FITC (Clone KM81) (rat IgG2a), Anti-Mouse CD44 |
| Technique: |
Fluorescein, mouses, Mouse |
| Isotype: |
IgG2a |
| Label: |
FITC |
| Species: |
Mouses, Mouse |
| Alternative name: |
fluorecein (clonality KM81) (rat IgG2a), antibody to-Mouse CD44 molecule (Indian blood group) |
| Alternative technique: |
murine |
| Alternative to gene target: |
CD44 and IDBG-39556 and ENSG00000026508 and 960, CD44 and IDBG-636564 and ENSBTAG00000011578 and 281057, CDW44 and CSPG8 and ECMR-III and HCELL and HUTCH-I and IN and LHR and MC56 and MDU2 and MDU3 and MIC4 and Pgp1, Cd44 and IDBG-193505 and ENSMUSG00000005087 and 12505, Cell surfaces, hyaluronic acid binding, signal transduction by p53 class mediator and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0044344 and cellular response to fibroblast growth factor stimulus and biological process this GO :0050731 and positive regulation of peptidyl-tyrosine phosphorylation and biological process this GO :0050900 and leukocyte migration and biological process this GO :0051216 and cartilage development and biological process this GO :0060333 and interferon-gamma-mediated signaling pathway and biological process this GO :0060442 and branching involved in prostate gland morphogenesis and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070374 and positive regulation of ERK1 and ERK2 cascade and biological process this GO :0070487 and monocyte aggregation and biological process this GO :1900625 and positive regulation of monocyte aggregation and biological process this GO :1902166 and negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator and biological process, this GO :0001658 and branching involved in ureteric bud morphogenesis and biological process this GO :0002246 and wound healing involved in inflammatory response and biological process this GO :0004415 and hyalurononglucosaminidase activity and molecular function this GO :0004888 and transmembrane signaling receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005518 and collagen binding and molecular function this GO :0005540 and hyaluronic acid binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0005975 and carbohydrate metabolic process and biological process this GO :0007155 and cell adhesion and biological process this GO :0007160 and cell-matrix adhesion and biological process this GO :0007596 and blood coagulation and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0010628 and positive regulation of gene expression and biological process this GO :0016020 and membrane and cellular component this GO :0016055 and Wnt signaling pathway and biological process this GO :0016323 and basolateral plasma membrane and cellular component this GO :0016337 and single organismal cell-cell adhesion and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0022617 and extracellular matrix disassembly and biological process this GO :0030198 and extracellular matrix organization and biological process this GO :0030203 and glycosaminoglycan metabolic process and biological process this GO :0030212 and hyaluronan metabolic process and biological process this GO :0030214 and hyaluronan catabolic process and biological process this GO :0033138 and positive regulation of peptidyl-serine phosphorylation and biological process this GO :0034116 and positive regulation of heterotypic cell-cell adhesion and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043154 and negative regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0043518 and negative regulation of DNA damage response, this GO :0004415 : hyalurononglucosaminidase activity, this GO :0004415 : hyalurononglucosaminidase activity and also this GO :0004888 : transmembrane signaling receptor activity and also this GO :0005515 : protein binding and also this GO :0005518 : collagen binding and also this GO :0005540 : hyaluronic acid binding, this GO :0004888 : transmembrane signaling receptor activity, this GO :0005515 : protein binding, this GO :0005518 : collagen binding, this GO :0005540 : hyaluronic acid binding, CD44 molecule (Indian blood group) |
| Identity: |
1681 |
| Gene: |
CD44 |
More about : CD44 |
| Long gene name: |
CD44 molecule (Indian blood group) |
| Synonyms gene: |
MIC4 MDU2 MDU3 |
| Synonyms gene name: |
CD44 antigen (homing function and Indian blood group system) |
| Synonyms: |
IN MC56 Pgp1 CD44R HCELL CSPG8 |
| Synonyms name: |
hematopoietic cell E- and L-selectin ligand chondroitin sulfate proteoglycan 8 |
| Locus: |
11p13 |
| Discovery year: |
1989-06-30 |
| GenBank acession: |
M59040 |
| Entrez gene record: |
960 |
| Pubmed identfication: |
2454887 |
| RefSeq identity: |
NM_000610 |
| Classification: |
Proteoglycans CD molecules Blood group antigens |
| Havana BLAST/BLAT: |
OTTHUMG00000044388 |
| Locus Specific Databases: |
LRG_815 |