| known also as: |
Anti-Rabbit Polyclonal (IgG) to Mouse RB1 / Retinoblastoma / RB |
| known also as: |
Rabbit PAb (IgG) to Murine RB1 / Retinoblastoma / RB |
| known also as: |
Lapin Polyclonal (IgG) to Mus musculus RB1 / Retinoblastoma / RB |
| known also as: |
RB1 / Retinoblastoma / RB |
| known also as: |
Mouse RB1, OSRC, Osteosarcoma, PRb, Pp110, RB, RB, RB1, Retinoblastoma, Retinoblastoma, Retinoblastoma 1, p105-Rb, Anti-RB1 / Retinoblastoma / RB Antibody (N-Terminus) IHC-plus |
| Other names: |
Rb, Retinoblastoma-associated protein, p105-Rb, pRb, pp110, prepro-retinoblastoma-associated protein, protein phosphatase 1, regulatory subunit 130, retinoblastoma 1, retinoblastoma suspectibility protein, retinoblastoma-associated protein, retinoblastoma-associated protein |
| Gene name: |
RB1 |
| Other gene names: |
OSRC, PPP1R130, RB, RB1, Rb, p105-Rb, pRb, pp110, RB1 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Mouse, Human |
| Specificity and cross-reactivity: |
N-terminal, Recombinant (partial) |
| Purification method: |
Immunoaffinity Purified |
| Form/Appearance: |
0, 50% glycerol, pH 7, 09% sodium azide, 2, Phosphate-buffered solution |
| Concentration: |
5 mg/ml |
| Storage and shipping: |
Avoid repeated freezing and thawing, or Store productone at -20 degrees Celsius, +Store productone at +4 degrees Celsius |
| Tested for:: |
Immunofluorescence (IF), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| About: |
2 light chains, For storage sodium azide is added or you can call us to request azide free antibody preparations, IgG, The IgG antibody has 2 , There are 2 heavy chains, These will need colder storage temperatures, They represent 70% or more of , This antibody can be antigen purified or protein A or G purified, goat polyclonal antibodies , mouse monoclonal H&, Immunoglobulin gamma, L chain clones or rabbit, antibodies, antigen , binding sites, have 4 parts, serum |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
PAb RB1 / Retinoblastoma / RB |
| Short name: |
PAb (IgG) Mouse RB1 / Retinoblastoma / RB Antibody |
| Technique: |
IgGs, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG |
| Species: |
Mouses, Mouse |
| Alternative name: |
polyclonal (Immunoglobulin G) to Mouse retinoblastoma 1 / Retinoblastoma / RB (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BT, DNA-templated and biological process this GO :0006469 and negative regulation of protein kinase activity and biological process this GO :0007050 and cell cycle arrest and biological process this GO :0007070 and negative regulation of transcription from RNA polymerase II promoter during mitosis and biological process this GO :0007093 and mitotic cell cycle checkpoint and biological process this GO :0007265 and Ras protein signal transduction and biological process this GO :0007346 and regulation of mitotic cell cycle and biological process this GO :0008134 and transcription factor binding and molecular function this GO :0008150 and biological process and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0016032 and viral process and biological process this GO :0016514 and SWI/SNF complex and cellular component this GO :0016605 and PML body and cellular component this GO :0019899 and enzyme binding and molecular function this GO :0019900 and kinase binding and molecular function this GO :0030182 and neuron differentiation and biological process this GO :0030521 and androgen receptor signaling pathway and biological process this GO :0031134 and sister chromatid biorientation and biological process this GO :0031175 and neuron projection development and biological process this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0034088 and maintenance of mitotic sister chromatid cohesion and biological process this GO :0034349 and glial cell apoptotic process and biological process this GO :0035189 and Rb-E2F complex and cellular component this GO :0035914 and skeletal muscle cell differentiation and biological process this GO :0042551 and neuron maturation and biological process this GO :0042802 and identical protein binding and molecular function this GO :0043353 and enucleate erythrocyte differentiation and biological process this GO :0043433 and negative regulation of sequence-specific DNA binding transcription factor activity and biological process this GO :0043550 and regulation of lipid kinase activity and biological process this GO :0045087 and innate immune response and biological process this GO :0045445 and myoblast differentiation and biological process this GO :0045651 and positive regulation of macrophage differentiation and biological process this GO :0045786 and negative regulation of cell cycle and biological process this GO :0045842 and positive regulation of mitotic metaphase/anaphase transition and biological process this GO :0045879 and negative regulation of smoothened signaling pathway and biological process this GO :0045892 and negative regulation of transcription, DNA-templated and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0048565 and digestive tract development and biological process this GO :0048667 and cell morphogenesis involved in neuron differentiation and biological process this GO :0050680 and negative regulation of epithelial cell proliferation and biological process this GO :0050681 and androgen receptor binding and molecular function this GO :0051146 and striated muscle cell differentiation and biological process this GO :0051219 and phosphoprotein binding and molecular function this GO :0051301 and cell division and biological process this GO :0051402 and neuron apoptotic process and biological process this GO :0051726 and regulation of cell cycle and biological process this GO :0071459 and protein localization to chromosome, OSRC and p105-Rb and pp110 and PPP1R130 and pRb and RB, RB1 and IDBG-32092 and ENSG00000139687 and 5925, Rb1 and IDBG-179829 and ENSMUSG00000022105 and 19645, centromeric region and biological process this GO :0071922 and regulation of cohesin localization to chromatin and biological process this GO :0071930 and negative regulation of transcription involved in G1/S transition of mitotic cell cycle and biological process this GO :0090230 and regulation of centromere complex assembly and biological process this GO :0097284 and hepatocyte apoptotic process and biological process this GO :2000134 and negative regulation of G1/S transition of mitotic cell cycle and biological process, nuclei, phosphoprotein binding, this GO :0000075 and cell cycle checkpoint and biological process this GO :0000082 and G1/S transition of mitotic cell cycle and biological process this GO :0000083 and regulation of transcription involved in G1/S transition of mitotic cell cycle and biological process this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0000278 and mitotic cell cycle and biological process this GO :0000785 and chromatin and cellular component this GO :0001047 and core promoter binding and molecular function this GO :0001102 and RNA polymerase II activating transcription factor binding and molecular function this GO :0003674 and molecular function and molecular function this GO :0003677 and DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0003713 and transcription coactivator activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005575 and cellular component and cellular component this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005667 and transcription factor complex and cellular component this GO :0005819 and spindle and cellular component this GO :0006338 and chromatin remodeling and biological process this GO :0006351 and transcription, this GO :0001047 : core promoter binding, this GO :0001047 : core promoter binding and also this GO :0001102 : RNA polymerase II activating transcription factor binding and also this GO :0003674 : molecular_function and also this GO :0003677 : DNA binding and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0003713 : transcription coactivator activity and also this GO :0005515 : protein binding and also this GO :0008134 : transcription factor binding and also this GO :0019899 : enzyme binding and also this GO :0019900 : kinase binding and also this GO :0031625 : ubiquitin protein ligase binding and also this GO :0042802 : identical protein binding and also this GO :0050681 : androgen receptor binding and also this GO :0051219 : phosphoprotein binding, this GO :0001102 : RNA polymerase II activating transcription factor binding, this GO :0003674 : molecular_function, this GO :0003677 : DNA binding, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0003713 : transcription coactivator activity, this GO :0005515 : protein binding, this GO :0008134 : transcription factor binding, this GO :0019899 : enzyme binding, this GO :0019900 : kinase binding, this GO :0031625 : ubiquitin protein ligase binding, this GO :0042802 : identical protein binding, this GO :0050681 : androgen receptor binding, this GO :0051219 : phosphoprotein binding, 68871 and IDBG-629082 and ENSBTAG00000006640 and 534712, retinoblastoma 1 |
| Identity: |
9884 |
| Gene: |
RB1 |
More about : RB1 |
| Long gene name: |
RB transcriptional corepressor 1 |
| Synonyms gene: |
OSRC |
| Synonyms gene name: |
osteosarcoma retinoblastoma 1 |
| Synonyms: |
RB PPP1R130 |
| Synonyms name: |
prepro-retinoblastoma-associated protein protein phosphatase 1, regulatory subunit 130 |
| Locus: |
13q14, 2 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
M15400 |
| Entrez gene record: |
5925 |
| Pubmed identfication: |
1857421 15057823 |
| RefSeq identity: |
NM_000321 |
| Classification: |
Endogenous ligands |
| Havana BLAST/BLAT: |
OTTHUMG00000016900 |
| Locus Specific Databases: |
RB1-LSDB LRG_517 |