| Long name: |
Polyclonal Antibody to Caspase 1 (CASP1) |
| Antigen: |
Caspase 1 (CASP1) |
| Other names: |
CASP-1, Caspase-1, ICE, IL-1 beta-converting enzyme, IL-1 beta-converting enzyme, IL-1BC, IL-1BC, Interleukin 1beta converting enzyme, Interleukin-1 beta convertase, Interleukin-1 beta-converting enzyme, beta, caspase 1, caspase-1, convertase, interleukin 1, interleukin-1 beta convertase, interleukin-1 beta-converting enzyme, p45, p45, caspase-1 |
| Gene name: |
CASP1, Caspase 1 (CASP1) |
| Gene synonims: |
CASP-1, Casp1, ICE, IL-1BC, Ice, Il1bc, Il1bc, Il1bce, Casp1 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal Antibodies |
| Clone: |
Not applicable to Polyclonal Antibodies |
| Reacts with: |
Due to limitted amount of tested species we cannot guarantee that no crossreactivity will occur |
| Specificity: |
, CASP1, It has been selected for its ability to recognize CASP1 in immunohistochemical staining andwestern blotting, The antibody is a rabbit polyclonal antibody raised against CASP1, This is an antibody designed to detect Caspase 1 (CASP1) |
| Purification method: |
This antibody was purified via Affinity Chromatography |
| Form/Appearance: |
containing 0, pH7, 02% NaN3, 4, 50% glycerol, Supplied as solution form in PBS |
| Concentration: |
2mg/ml |
| Storage, shipping and handling: |
Avoid cycles of freezing and thawing as they may denaturate the polypeptide chains of the antibody, Due to transportation or handling reasons, For longer periods of time we recommend keeping the vial frozen at -40 or -80, Upon receving, We recommend you to briefly cetrifuge the vial prior to use to gather the content on the bottom, freeze at -20, small amounts of the antibody might get caught on the lid or walls of the vial, The antibody is shipped at +4 degrees Celsius |
| Applications: |
EIA, ELI-Spot, ELISA, IFA, Immunohistochemistry (IHC) - Formalin/Paraffin, Western Blot (WB), Immunocytochemistry (ICC) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals they should be stored frozen at - 24° |
| Gene target: |
Caspase 1 (CASP1) |
| Short name: |
Anti- Caspase 1 (CASP1) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
apoptosis-related cysteine peptidase) (Antibody to), Antibody to caspase 1 (caspase 1 |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CASP1 and IDBG-69618 and ENSG00000137752 and 834, Casp1 and IDBG-131590 and ENSMUSG00000025888 and 12362, Extracellular, ICE and IL1BC and P45, apoptosis-related cysteine peptidase, cysteine-type endopeptidase activator activity involved in apoptotic process, leucine rich repeat containing receptor signaling pathway and biological process this GO :0042981 and regulation of apoptotic process and biological process this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0045087 and innate immune response and biological process this GO :0050715 and positive regulation of cytokine secretion and biological process this GO :0050717 and positive regulation of interleukin-1 alpha secretion and biological process this GO :0050718 and positive regulation of interleukin-1 beta secretion and biological process this GO :0050727 and regulation of inflammatory response and biological process this GO :0051882 and mitochondrial depolarization and biological process this GO :0060081 and membrane hyperpolarization and biological process this GO :0070269 and pyroptosis and biological process this GO :0071260 and cellular response to mechanical stimulus and biological process this GO :0071310 and cellular response to organic substance and biological process this GO :0072557 and IPAF inflammasome complex and cellular component this GO :0072558 and NLRP1 inflammasome complex and cellular component this GO :0072559 and NLRP3 inflammasome complex and cellular component this GO :0097169 and AIM2 inflammasome complex and cellular component this GO :0097194 and execution phase of apoptosis and biological process this GO :0097300 and programmed necrotic cell death and biological process, this GO :0001666 and response to hypoxia and biological process this GO :0004175 and endopeptidase activity and molecular function this GO :0004197 and cysteine-type endopeptidase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005622 and intracellular and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006508 and proteolysis and biological process this GO :0006915 and apoptotic process and biological process this GO :0006919 and activation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0007165 and signal transduction and biological process this GO :0008233 and peptidase activity and molecular function this GO :0008234 and cysteine-type peptidase activity and molecular function this GO :0008656 and cysteine-type endopeptidase activator activity involved in apoptotic process and molecular function this GO :0016485 and protein processing and biological process this GO :0032496 and response to lipopolysaccharide and biological process this GO :0032611 and interleukin-1 beta production and biological process this GO :0033198 and response to ATP and biological process this GO :0035872 and nucleotide-binding domain, this GO :0004175 : endopeptidase activity, this GO :0004175 : endopeptidase activity and also this GO :0004197 : cysteine-type endopeptidase activity and also this GO :0005515 : protein binding and also this GO :0008233 : peptidase activity and also this GO :0008234 : cysteine-type peptidase activity and also this GO :0008656 : cysteine-type endopeptidase activator activity involved in apoptotic process, this GO :0004197 : cysteine-type endopeptidase activity, this GO :0005515 : protein binding, this GO :0008233 : peptidase activity, this GO :0008234 : cysteine-type peptidase activity, this GO :0008656 : cysteine-type endopeptidase activator activity involved in apoptotic process, caspase 1 |
| Identity: |
1499 |
| Gene: |
CASP1 |
More about : CASP1 |
| Long gene name: |
caspase 1 |
| Synonyms gene: |
IL1BC |
| Synonyms gene name: |
apoptosis-related cysteine peptidase , apoptosis-related cysteine peptidase (interleukin 1, apoptosis-related cysteine protease (interleukin 1, beta, beta, caspase 1, convertase) caspase 1, convertase) caspase 1 |
| Synonyms: |
ICE |
| Synonyms name: |
beta, caspase-1 interleukin 1, convertase |
| Locus: |
11q22, 3 |
| Discovery year: |
1992-05-07 |
| GenBank acession: |
U13697 |
| Entrez gene record: |
834 |
| Pubmed identfication: |
1373520 9250871 |
| RefSeq identity: |
NM_033292 |
| Classification: |
Caspase recruitment domain containing Caspases |
| Havana BLAST/BLAT: |
OTTHUMG00000048072 |