| known also as: |
Anti-Rabbit Polyclonal to Human CASP1 / Caspase 1 |
| known also as: |
Rabbit PAb to Human CASP1 / Caspase 1 |
| known also as: |
Lapin Polyclonal to Homo sapiens CASP1 / Caspase 1 |
| known also as: |
CASP1 / Caspase 1 |
| known also as: |
CASP-1, CASP1, CASP1 nirs variant 1, Caspase 1, Caspase 1, Caspase-1, Human CASP1, ICE, ICE-like protease, IL-1 beta-converting enzyme, IL-1BC, IL1B-convertase, IL1BC, IL1BCE, Interleukin-1 beta convertase, p45, Anti-CASP1 / Caspase 1 Antibody (C-Terminus) IHC-plus |
| Other names: |
CASP1 nirs variant 1, Caspase-1, Caspase-1 subunit p10, ICE, IL-1 beta-converting enzyme, IL-1 beta-converting enzyme, IL-1BC, IL1B-convertase, Interleukin-1 beta convertase, Interleukin-1 beta-converting enzyme, apoptosis-related cysteine peptidase, apoptosis-related cysteine peptidase (interleukin 1, beta, beta, caspase 1, caspase 1, caspase-1, convertase, convertase), interleukin 1, interleukin 1-B converting enzyme, p45Cleaved into the following 2 chains:Caspase-1 subunit p20, caspase-1 isoform beta |
| Gene name: |
CASP1 |
| Other gene names: |
CASP-1, CASP1, ICE, ICE, IL-1 beta-converting enzyme, IL-1BC, IL1BC, IL1BC, IL1BCE, P45, CASP1 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
16 amino acid peptide from near the carboxy-terminus of human Caspase-1 |
| Purification method: |
Immunoaffinity Purified |
| Form/Appearance: |
0, 02% sodium azide, PBS |
| Concentration: |
1 miligram per 1 mililiter |
| Storage and shipping: |
Store undiluted, avoid freeze thaw cycles, long term aliquot and store productone should be stored at -20 degrees Celsius, Short term Store productone at +4 degrees Celsius |
| Tested for:: |
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, Homo sapiens sapiens), Human proteins, humans , ssp |
| Gene target: |
CASP1 / Caspase 1 |
| Short name: |
Anti- CASP1 / Caspase 1 |
| Species: |
Humans, Human |
| Alternative name: |
apoptosis-related cysteine peptidase / caspase 1, sapiens caspase 1, antibody to-H |
| Alternative to gene target: |
CASP1 and IDBG-69618 and ENSG00000137752 and 834, Casp1 and IDBG-131590 and ENSMUSG00000025888 and 12362, Extracellular, ICE and IL1BC and P45, apoptosis-related cysteine peptidase, cysteine-type endopeptidase activator activity involved in apoptotic process, leucine rich repeat containing receptor signaling pathway and biological process this GO :0042981 and regulation of apoptotic process and biological process this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0045087 and innate immune response and biological process this GO :0050715 and positive regulation of cytokine secretion and biological process this GO :0050717 and positive regulation of interleukin-1 alpha secretion and biological process this GO :0050718 and positive regulation of interleukin-1 beta secretion and biological process this GO :0050727 and regulation of inflammatory response and biological process this GO :0051882 and mitochondrial depolarization and biological process this GO :0060081 and membrane hyperpolarization and biological process this GO :0070269 and pyroptosis and biological process this GO :0071260 and cellular response to mechanical stimulus and biological process this GO :0071310 and cellular response to organic substance and biological process this GO :0072557 and IPAF inflammasome complex and cellular component this GO :0072558 and NLRP1 inflammasome complex and cellular component this GO :0072559 and NLRP3 inflammasome complex and cellular component this GO :0097169 and AIM2 inflammasome complex and cellular component this GO :0097194 and execution phase of apoptosis and biological process this GO :0097300 and programmed necrotic cell death and biological process, this GO :0001666 and response to hypoxia and biological process this GO :0004175 and endopeptidase activity and molecular function this GO :0004197 and cysteine-type endopeptidase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005622 and intracellular and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006508 and proteolysis and biological process this GO :0006915 and apoptotic process and biological process this GO :0006919 and activation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0007165 and signal transduction and biological process this GO :0008233 and peptidase activity and molecular function this GO :0008234 and cysteine-type peptidase activity and molecular function this GO :0008656 and cysteine-type endopeptidase activator activity involved in apoptotic process and molecular function this GO :0016485 and protein processing and biological process this GO :0032496 and response to lipopolysaccharide and biological process this GO :0032611 and interleukin-1 beta production and biological process this GO :0033198 and response to ATP and biological process this GO :0035872 and nucleotide-binding domain, this GO :0004175 : endopeptidase activity, this GO :0004175 : endopeptidase activity and also this GO :0004197 : cysteine-type endopeptidase activity and also this GO :0005515 : protein binding and also this GO :0008233 : peptidase activity and also this GO :0008234 : cysteine-type peptidase activity and also this GO :0008656 : cysteine-type endopeptidase activator activity involved in apoptotic process, this GO :0004197 : cysteine-type endopeptidase activity, this GO :0005515 : protein binding, this GO :0008233 : peptidase activity, this GO :0008234 : cysteine-type peptidase activity, this GO :0008656 : cysteine-type endopeptidase activator activity involved in apoptotic process, caspase 1 |
| Identity: |
1499 |
| Gene: |
CASP1 |
More about : CASP1 |
| Long gene name: |
caspase 1 |
| Synonyms gene: |
IL1BC |
| Synonyms gene name: |
apoptosis-related cysteine peptidase , apoptosis-related cysteine peptidase (interleukin 1, apoptosis-related cysteine protease (interleukin 1, beta, beta, caspase 1, convertase) caspase 1, convertase) caspase 1 |
| Synonyms: |
ICE |
| Synonyms name: |
beta, caspase-1 interleukin 1, convertase |
| Locus: |
11q22, 3 |
| Discovery year: |
1992-05-07 |
| GenBank acession: |
U13697 |
| Entrez gene record: |
834 |
| Pubmed identfication: |
1373520 9250871 |
| RefSeq identity: |
NM_033292 |
| Classification: |
Caspase recruitment domain containing Caspases |
| Havana BLAST/BLAT: |
OTTHUMG00000048072 |