| Long name: |
Biotin Conjugated, Acetyl Lysine Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Acetyl Lysine |
| Specificity: |
This is a highly specific antibody against Acetyl Lysine |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated acetyl Lysine |
| Tested applications: |
WB |
| Recommended dilutions: |
WB(1:100-1000) |
| Crossreactivity: |
Others |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Acetylation may result in structural transitions as well as specific signaling within discrete chromatin domains, Acetylation of lysine residues within proteins has emerged as an important mechanism used by cells to overcome this repression, DNA is tightly packed into nucleosomes generating an environment which is highly repressive towards DNA processes such as transcription, DNA repair, DNA replication, Furthermore, More than 20 acetyltransferases and 18 deacetylases have been identified so far, Over 40 transcription factors and 30 other nuclear, The acetylation of non-histone proteins such as transcription factors, The reversible lysine acetylation of histones and non-histone proteins plays a vital role in the regulation of many cellular processes including chromatin dynamics and transcription, The role of acetylation in intracellular signaling has been inferred from the binding of acetylated peptides by the conserved bromodomain, and neuronal repression, and viral proteins have been shown to be acetylated in vivo, apoptosis, as well as histones appears to be involved in this process, bacterial, but the mechanistic details of substrate selection and site specificity of these enzymes remain unclear, cell cycle progression, cytoplasmic, differentiation, gene silencing, nuclear import, recent findings suggest that bromodomain/acetylated-lysine recognition can serve as a regulatory mechanism in protein-protein interactions in numerous cellular processes such as chromatin remodeling and transcriptional activation, In the nucleus |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
Acetyl Lysine |
| Description: |
Conjugated by NATs, N terminal acetylation or CH3CO as epigenetic regulation of Lysine Antibody |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Lysine Conjugated |
| Short name: |
Conjugated, Lysine Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, Acetyl Lysine (Antibody to) |
| Alternative technique: |
antibodies |