| Long name: |
Acetyl Lysine Primary Polyclonal Antibody |
| Also known as: |
Acetyl Lysine PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Acetyl Lysine |
| Specificity: |
This is a highly specific antibody against Acetyl Lysine |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated acetyl Lysine |
| Tested Applications: |
WB |
| Recommended dilutions: |
WB(1:100-1000) |
| Cross reactivity: |
Others |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Acetylation may result in structural transitions as well as specific signaling within discrete chromatin domains, Acetylation of lysine residues within proteins has emerged as an important mechanism used by cells to overcome this repression, DNA is tightly packed into nucleosomes generating an environment which is highly repressive towards DNA processes such as transcription, DNA repair, DNA replication, Furthermore, More than 20 acetyltransferases and 18 deacetylases have been identified so far, Over 40 transcription factors and 30 other nuclear, The acetylation of non-histone proteins such as transcription factors, The reversible lysine acetylation of histones and non-histone proteins plays a vital role in the regulation of many cellular processes including chromatin dynamics and transcription, The role of acetylation in intracellular signaling has been inferred from the binding of acetylated peptides by the conserved bromodomain, and neuronal repression, and viral proteins have been shown to be acetylated in vivo, apoptosis, as well as histones appears to be involved in this process, bacterial, but the mechanistic details of substrate selection and site specificity of these enzymes remain unclear, cell cycle progression, cytoplasmic, differentiation, gene silencing, nuclear import, recent findings suggest that bromodomain/acetylated-lysine recognition can serve as a regulatory mechanism in protein-protein interactions in numerous cellular processes such as chromatin remodeling and transcriptional activation, In the nucleus |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
Acetyl Lysine |
| Description: |
N terminal acetylation or CH3CO as epigenetic regulation of Lysine Antibody by NATs |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Lysine |
| Short name: |
Lysine Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Acetyl Lysine (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
37098 |
| Gene: |
KDM4E |
More about : KDM4E |
| Long gene name: |
lysine demethylase 4E |
| Synonyms gene: |
KDM4DL |
| Synonyms gene name: |
lysine (K)-specific demethylase 4D-like lysine (K)-specific demethylase 4E |
| Synonyms: |
JMJD2E KDM5E |
| Locus: |
11q21 |
| Discovery year: |
2009-06-12 |
| GenBank acession: |
BC157851 |
| Entrez gene record: |
390245 |
| Pubmed identfication: |
21076780 |
| RefSeq identity: |
NM_001161630 |
| Classification: |
Lysine demethylases |
| Havana BLAST/BLAT: |
OTTHUMG00000167858 |