| Long name: |
FITC Conjugated, AIF1 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
AIF1 |
| Specificity: |
This is a highly specific antibody against AIF1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
116-147/147 |
| Subcellular location: |
Membrane bound, Cytoplasm |
| Source: |
KLH conjugated synthetic peptide derived from human AIF1 |
| Gene ID number: |
199 |
| Swiss Prot: |
P55008 |
| Tested applications: |
IF(IHC-F), IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-F)(1:50-200), IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Binds calcium, Enhances lymphocyte migration, Enhances the actin-bundling activity of LCP1, May play a role in macrophage activation and function, Plays a role in RAC signaling and in phagocytosis, Plays a role in vascular inflammation, Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes, Actin-binding protein that enhances membrane ruffling and RAC activation |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
IRT-1 AIF-1 Em:AF129756, 17 IBA1 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
AIF1 Conjugated |
| Short name: |
FITC Conjugated, AIF1 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, allograft inflammatory factor 1 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
AIF-1 and IBA1 and IRT-1 and IRT1, AIF1 and IDBG-634144 and ENSBTAG00000020554 and 280989, AIF1 and IDBG-78190 and ENSG00000204472 and 199, Aif1 and IDBG-177226 and ENSMUSG00000024397 and 11629, actin filament binding, engulfment and biological process this GO :0006954 and inflammatory response and biological process this GO :0010629 and negative regulation of gene expression and biological process this GO :0014739 and positive regulation of muscle hyperplasia and biological process this GO :0016601 and Rac protein signal transduction and biological process this GO :0030027 and lamellipodium and cellular component this GO :0030041 and actin filament polymerization and biological process this GO :0030335 and positive regulation of cell migration and biological process this GO :0031668 and cellular response to extracellular stimulus and biological process this GO :0032587 and ruffle membrane and cellular component this GO :0032870 and cellular response to hormone stimulus and biological process this GO :0034097 and response to cytokine and biological process this GO :0042102 and positive regulation of T cell proliferation and biological process this GO :0042995 and cell projection and cellular component this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043204 and perikaryon and cellular component this GO :0045429 and positive regulation of nitric oxide biosynthetic process and biological process this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0048661 and positive regulation of smooth muscle cell proliferation and biological process this GO :0048662 and negative regulation of smooth muscle cell proliferation and biological process this GO :0048678 and response to axon injury and biological process this GO :0051015 and actin filament binding and molecular function this GO :0051017 and actin filament bundle assembly and biological process this GO :0051602 and response to electrical stimulus and biological process this GO :0071315 and cellular response to morphine and biological process this GO :0071346 and cellular response to interferon-gamma and biological process this GO :0071447 and cellular response to hydroperoxide and biological process this GO :0071672 and negative regulation of smooth muscle cell chemotaxis and biological process this GO :0071673 and positive regulation of smooth muscle cell chemotaxis and biological process this GO :0090026 and positive regulation of monocyte chemotaxis and biological process this GO :0097178 and ruffle assembly and biological process this GO :1900087 and positive regulation of G1/S transition of mitotic cell cycle and biological process this GO :2000406 and positive regulation of T cell migration and biological process, nuclei, this GO :0001726 and ruffle and cellular component this GO :0001774 and microglial cell activation and biological process this GO :0001891 and pha this GO cytic cup and cellular component this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0003674 and molecular function and molecular function this GO :0005509 and calcium ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005884 and actin filament and cellular component this GO :0006911 and pha this GO cytosis, this GO :0003674 : molecular_function, this GO :0003674 : molecular_function and also this GO :0005509 : calcium ion binding and also this GO :0005515 : protein binding and also this GO :0051015 : actin filament binding, this GO :0005509 : calcium ion binding, this GO :0005515 : protein binding, this GO :0051015 : actin filament binding, allograft inflammatory factor 1 |
| Identity: |
352 |
| Gene: |
AIF1 |
More about : AIF1 |
| Long gene name: |
allograft inflammatory factor 1 |
| Synonyms name: |
interferon gamma responsive transcript ionized calcium-binding adapter molecule 1 |
| Locus: |
6p21, 33 |
| Discovery year: |
1997-07-01 |
| GenBank acession: |
U19713 |
| Entrez gene record: |
199 |
| Pubmed identfication: |
8912632 |
| Classification: |
EF-hand domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000031246 |