| Long name: |
EMR2/CD312 Primary Polyclonal Antibody |
| Also known as: |
EMR2/CD312 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
EMR2/CD312 |
| Specificity: |
This is a highly specific antibody against EMR2/CD312 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human EMR2/CD312 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Derived from the processing of a single polypeptide, EGF-TM7 receptors are a family of class B, EGF-TM7 receptors interact with cellular ligands such as CD55 and chondroitin sulfate, EMR2 is a heptahelical molecule predominantly expressed on cells of the immune system such as leukocytes, EMR2 is a member of the EGF-TM7 receptor subfamily, EMR2 is proteo-lytically cleaved into two separate subunits: a seven-transmembrane subunit, G protein-coupled receptors, Through a variable number of N-terminal EGF-like domains, Within the TM7 superfamily, and an extracellular Alpha subunit, seven-span transmembrane (TM7) receptors predominantly expressed by cells of the immune system, the molecular structure and ligand-binding properties of EGF-TM7 receptors are unique, they are expressed at the cell surface as heterodimers consisting of a large extracellular region associated with a TM7 moiety, which includes CD97 and EMR2, The epidermal growth factor (EGF) family constitutes a group of class B |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
CD 312 antigen, CD312, CD312 antigen, EGF like module EMR2, EGF-like module receptor 2, EGF-like module-containing mucin-like hormone receptor-like 2, EMR2, EMR2_HUMAN, Egf like module containing mucin like hormone receptor like 2, Egf like module containing mucin like hormone receptor like sequence 2, CD 312 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
EMR2/CD312 |
| Short name: |
EMR2/CD312 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
EMR2/CD312 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
3337 |
| Gene: |
ADGRE2 |
More about : ADGRE2 |
| Long gene name: |
adhesion G protein-coupled receptor E2 |
| Synonyms gene: |
EMR2 |
| Synonyms gene name: |
egf-like module containing, hormone receptor-like 2 , hormone receptor-like sequence 2 egf-like module containing, mucin-like, mucin-like |
| Synonyms: |
CD312 |
| Locus: |
19p13, 12 |
| Discovery year: |
2000-03-14 |
| GenBank acession: |
AF114491 |
| Entrez gene record: |
30817 |
| Pubmed identfication: |
25713288 |
| Classification: |
CD molecules Adhesion G protein-coupled receptors, subfamily E |
| Havana BLAST/BLAT: |
OTTHUMG00000183408 |