| Long name: |
ALEXA FLUOR 647 Conjugated, DOK7 Polyclonal Antibody |
| Also known as: |
Anti-DOK7 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
DOK7 |
| Specificity: |
This is a highly specific antibody against DOK7 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DOK7 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Based on their similarities, Dok-4/5/6 and Dok-7, Dok-7 is crucial for neuromuscular synaptogenesis and for MuSK activation, Mice lacking Dok-7 do not form neuromuscular synapses nor acetylcholine receptor clusters, Mutations in the Dok-7 gene can cause congenital myasthenic syndromes (CMA) â, Through its interaction with muscle-specific receptor kinase (MuSK), recessively inherited disorders characterized by muscle weakness, the Dok family of proteins can be divided into three subgroups: Dok-1/2/3, which contain multiple tyrosine residues and putative SH2 binding sites, &euro, &euro, &euro, &oelig, &rdquo, The downstream of kinase family (Dok1-7) are members of a class of â, dockingâ, proteins that include the tyrosine kinase substrates IRS-1 and Cas |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
FLJ33718 FLJ39137 Dok-7 |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the DOK7 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
DOK7 |
| Short name: |
DOK7 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, DOK7 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
26594 |
| Gene: |
DOK7 |
More about : DOK7 |
| Long gene name: |
docking protein 7 |
| Synonyms gene: |
C4orf25 |
| Synonyms gene name: |
chromosome 4 open reading frame 25 |
| Locus: |
4p16, 3 |
| Discovery year: |
2006-05-22 |
| GenBank acession: |
AK091037 |
| Entrez gene record: |
285489 |
| Pubmed identfication: |
16794080 |
| RefSeq identity: |
NM_173660 |
| Havana BLAST/BLAT: |
OTTHUMG00000122087 |
| Locus Specific Databases: |
Leiden Muscular Dystrophy pages LRG_869 |