| Long name: |
GPR45 Primary Polyclonal Antibody |
| Also known as: |
GPR45 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
GPR45 |
| Specificity: |
This is a highly specific antibody against GPR45 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GPR45 |
| Gene ID number: |
11250 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
G protein receptor 54 (GPR54), GRP54 is expressed in the liver, In the rat, Mutations in GPCR54 are associated with a lack of puberty onset and autosomal recessive idiopathic hypogonadotropic hypogonadism, Proper function of GRP54 is essential for puberty, Their diverse biological functions range from vision and olfaction to neuronal and endocrine signaling and are involved in many pathological conditions, a deficient or decreased function of the gonads, a member of the rhodopsin family of GCPRs, also designated seven transmembrane (7TM) receptors and heptahelical receptors, and calcium ions, are a protein family which interact with G proteins (heterotrimeric GTPases) to synthesize intracellular second messengers such as diacylglycerol, cyclic AMP, inositol phosphates, intestine and most areas of the brain, is the receptor for the Kiss1 gene product, metastin, pancreas and spinal cord, pituitary, while in the human it is expressed in the placenta, G protein-coupled receptors (GPCRs) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
GPCR 45, High affinity lysophosphatidic acid receptor, PSP24, PSP24 1, PSP24 alpha, PSP241, PSP24A, PSP24ALPHA, Probable G protein coupled receptor 45, G protein coupled receptor 45 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
GPR45 |
| Short name: |
GPR45 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
GPR45 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
4503 |
| Gene: |
GPR45 |
More about : GPR45 |
| Long gene name: |
G protein-coupled receptor 45 |
| Synonyms: |
PSP24 PSP24A |
| Locus: |
2q12, 1 |
| Discovery year: |
1999-03-12 |
| GenBank acession: |
AF118266 |
| Entrez gene record: |
11250 |
| Pubmed identfication: |
10036181 |
| RefSeq identity: |
NM_007227 |
| Classification: |
Class A orphans , G protein-coupled receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000130805 |