| Long name: |
HRP Conjugated, GPR43 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
HRP Conjugated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
GPR43 |
| Specificity: |
This is a highly specific antibody against GPR43 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
63-84/330 |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human GPR43 |
| Gene ID number: |
2867 |
| Swiss Prot: |
O15552 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Finally, G(i/o)-alpha family of G proteins but also to the Gq family (PubMed:12496283, In addition to SCFAs, In omnivorous mammals, In parallel to its role in energy homeostasis, Its activation results in the formation of inositol 1, May also play a role in the resolution of the inflammatory response and control chemotaxis in neutrophils, May also regulate the production of LEP/Leptin, May play a role in glucose homeostasis by regulating the secretion of GLP-1, PubMed:12711604, PubMed:23589301), SCFAs serve as a source of energy but also act as signaling molecules, That G protein-coupled receptor is probably coupled to the pertussis toxin-sensitive, a hormone acting on the central nervous system to inhibit food intake, and that plays a role in the regulation of whole-body energy homeostasis and in intestinal immunity, in response to short-chain fatty acids accumulating in the intestine, may also be activated by the extracellular lectin FCN1 in a process leading to activation of monocytes and inducing the secretion of interleukin-8/IL-8 in response to the presence of microbes (PubMed:21037097), may also mediate the activation of the inflammatory and immune responses by SCFA in the intestine, may also regulate whole-body energy homeostasis through adipogenesis regulating both differentiation and lipid storage of adipocytes, propionate and butyrate are produced primarily by the gut microbiome that metabolizes dietary fibers, regulating the rapid production of chemokines and cytokines, the mobilization of intracellular calcium, the phosphorylation of the MAPK3/ERK1 and MAPK1/ERK2 kinases and the inhibition of intracellular cAMP accumulation, the short chain fatty acids (SCFAs), the short chain fatty acids acetate, 4, 5-trisphosphate, G protein-coupled receptor that is activated by a major product of dietary fiber digestion |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% Gentamicin, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
FFA2R |
| Properties: |
Also monoclonal HRP conjugates are often used for Western Blot, HRP conjugates are often primary rabbit polyclonal antibodies couples to the , found in the roots of , (HRP), C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°, enzyme , horseradish, horseradish peroxidase |
| Gene target: |
GPR43 Conjugated |
| Short name: |
Conjugated, GPR43 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
HRP |
| Alternative name: |
horseradish peroxidase coupled, GPR43 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
4501 |
| Gene: |
FFAR2 |
More about : FFAR2 |
| Long gene name: |
free fatty acid receptor 2 |
| Synonyms gene: |
GPR43 |
| Synonyms gene name: |
G protein-coupled receptor 43 |
| Locus: |
19q13, 12 |
| Discovery year: |
1997-10-10 |
| GenBank acession: |
AF024690 |
| Entrez gene record: |
2867 |
| Pubmed identfication: |
9344866 |
| RefSeq identity: |
NM_005306 |
| Classification: |
Free fatty acid receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000183303 |